A5075116622- Escherichia coli research studies
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Bacteriophages and microbial interactions
- Pharmaceutical and Antibiotic Environmental Impacts
- Antimicrobial Resistance in Staphylococcus
- Microbial infections and disease research
- Probiotics and Fermented Foods
- Viral gastroenteritis research and epidemiology
- Bacterial Genetics and Biotechnology
- Salmonella and Campylobacter epidemiology
- Antimicrobial Peptides and Activities
- Enzyme Production and Characterization
- Aquaculture disease management and microbiota
- Genomics and Phylogenetic Studies
- Glycosylation and Glycoproteins Research
- Gut microbiota and health
- Herpesvirus Infections and Treatments
- Microbial Metabolites in Food Biotechnology
- Microbial Metabolism and Applications
- Bacterial biofilms and quorum sensing
- RNA and protein synthesis mechanisms
- Urinary Tract Infections Management
- Streptococcal Infections and Treatments
- Infant Nutrition and Health
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2023-2025
Universidade do Porto
2024-2025
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2017-2023
GlaxoSmithKline (Italy)
2020-2023
Génétique, Diversité, Écophysiologie des Céréales
2023
Microbiologie Environnement Digestif Santé
2017-2020
Université Clermont Auvergne
2020
Toscana Life Sciences
2020
GlaxoSmithKline (United Kingdom)
2017-2018
GlaxoSmithKline (Netherlands)
2016-2017
Wall teichoic acids (WTAs) from the major Gram-positive foodborne pathogen Listeria monocytogenes are peptidoglycan-associated glycopolymers decorated by monosaccharides that, while not essential for bacterial growth, required virulence and resistance to antimicrobials. Here we report structure function of a WTAs rhamnosyltransferase, RmlT, strictly L. rhamnosylation. In particular, demonstrated that RmlT transfers rhamnose dTDP-L-rhamnose naked WTAs, specificity towards TDP-rhamnose is...
The aim of this study was to report the antimicrobial resistance, molecular mechanisms associated and detection virulence determinants within faecal Enterococcus spp. Escherichia coli isolates Iberian wolf. Enterococci (n = 227) E. 195) were obtained from samples wolf (Canis lupus signatus). High rates resistance detected for tetracycline erythromycin among enterococci isolates, most resistant harboured tet(M) and/or tet(L) erm(B) genes, respectively. blaTEM, tet(A) tet(B), aadA or strA-strB...
The intensive use of antibiotics in human and veterinary medicine, associated with mechanisms bacterial genetic transfer, caused a selective pressure that contributed to the dissemination antimicrobial resistance different bacteria groups throughout ecosystems. Iberian wolf, due his predatory wild nature, may serve as an important indicator environmental contamination resistant bacteria. aim this study was characterize diversity extended-spectrum β-lactamase (ESBL)-producing Escherichia coli...
For many years Staphylococcus aureus has been recognized as an important human pathogen. In this study, the surfacome and exoproteome of a clinical sample MRSA was analyzed. The C2355 strain, previously typed ST398 spa-t011 showing phenotype multiresistance to antibiotics, several resistance genes. Using shotgun proteomics bioinformatics tools, 236 proteins were identified in surfaceome 99 exoproteome. Although these are related basic cell functions, some virulence pathogenicity like...
A total of 98 faecal samples from captive specimens Iberian lynx were collected and analysed for enterococci (96 isolates) Escherichia coli (90 recovery. These 186 isolates tested antimicrobial resistance, molecular mechanisms detection virulence genes. Among the enterococci, Enterococcus hirae was most prevalent species (35 isolates), followed by faecalis (30 faecium (27 durans (4 isolates). High rates resistance to tetracycline, erythromycin high-level-kanamycin detected among enterococcal...
Proteomics can be used to study the metabolic pathways and mechanisms involved in antimicrobial resistance. The aim of this comparative proteomic was establish overall changes proteome a naturally occurring ESBL-producing E. coli strain (C5478) stressed with its minimal inhibitory concentration (2 μg/mL) cefotaxime, compared same without stress, by using 2-D gel electrophoresis (2-DE) followed matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS)....
Escherichia coli is a versatile commensal species of the animal gut that can also be pathogen able to cause intestinal and extraintestinal infections. The plasticity its genome has led evolution pathogenic strains, which represent threat global health. Additionally, E. strains are major drivers antibiotic resistance, highlighting urgent need for new treatment prevention measures. antigenic structural heterogeneity enterohaemorrhagic colonisation factors limited their use development...
Abstract Wall teichoic acids (WTA) from the major Gram-positive foodborne pathogen Listeria monocytogenes are peptidoglycan-associated glycopolymers decorated by monosaccharides that, while not essential for bacterial growth, required virulence and resistance. Here we report first structure function of a WTA rhamnosyltransferase, RmlT, strictly L. rhamnosylation. We demonstrated that RmlT transfers rhamnose TDP-rhamnose to naked WTA, specificity towards is kinetically determined. solved...
Proteome analysis is a tool that can be used to visualize and, also, compare complex mixtures of proteins, and acquire important information about the individual proteins concerned in speci/c biological responses [1]. Proteomic de/ned as expressed complement genome. In com-parison genome, proteome de/ne se-ries by certain organism, under cer-tain conditions, serving unique informative infor-