A5088995202- Receptor Mechanisms and Signaling
- Knowledge Management and Sharing
- Child Development and Digital Technology
- Impact of Technology on Adolescents
- Mass Spectrometry Techniques and Applications
- Communication in Education and Healthcare
- Online and Blended Learning
- Diaspora, migration, transnational identity
- International Student and Expatriate Challenges
- Neuropeptides and Animal Physiology
- Public Relations and Crisis Communication
- Cultural Competency in Health Care
- Mentoring and Academic Development
- Management and Organizational Studies
- Social Media and Politics
- Ethics in Business and Education
- Breastfeeding Practices and Influences
- Protein Kinase Regulation and GTPase Signaling
- Advanced Photocatalysis Techniques
- Interpreting and Communication in Healthcare
- Racial and Ethnic Identity Research
- Ovarian function and disorders
- Adolescent Sexual and Reproductive Health
- Migration and Labor Dynamics
- Personal Information Management and User Behavior
Tianjin University
2022-2025
Kutztown University
2017-2023
Ministry of Housing and Urban-Rural Development
2022
Chang'an University
2022
Albion College
2008-2015
Purpose The study was designed to generate and test a model of employee cynicism toward organizational change from the communication perspective in higher education institution. Design/methodology/approach Using theoretical framework social information processing (SIP), investigated processes context, which contributed setting. Path analysis used overall fit. Findings findings suggest that three variables, perceived quality information, colleagues, trust administration, predict...
Purpose This study aims to construct and empirically test a theoretical model of mediated relationship between ethical leadership organizational cynicism. Design/methodology/approach From communication perspective, this examines the underlying mechanism association A cross-sectional survey was sent participants in different occupations. Path analysis used overall fit. Findings The results indicate that has both direct indirect effect on cynicism through mediating role leader-member exchange...
Agonists selectively targeting cannabinoid receptor-like G-protein-coupled receptor (GPCR) GPR119 hold promise for treating metabolic disorders while avoiding unwanted side effects. Here we present the cryo-electron microscopy (cryo-EM) structures of human GPR119-Gs signaling complexes bound to AR231453 and MBX-2982, two representative agonists reported GPR119. The reveal a one-amino acid shift conserved proline residue TM5 that forms an outward bulge, opening up hydrophobic cavity between...
Hydroxy-carboxylic acid receptors HCA1, HCA2, and HCA3 can be activated by important intermediates of energy metabolism. Despite the research focusing on its clinical application has been limited adverse effects. Therefore, role HCA1 as a promising target for treatment lipolysis warrants further exploration. As HCAs exhibit high similarity when with diverse selective agonists, conserved yet unique activation mechanism remains undisclosed. Herein, we unveil cryo-electron microscopy structures...
The rhodopsin-like receptor GPR119 plays a crucial role in glucose homeostasis and is an emerging target for the treatment of type 2 diabetes mellitus. In this study, we analyzed structure with agonist APD597 bound complex downstream G protein trimer by single particle cryo-electron microscopy (cryo-EM). Structural comparison combination function assay revealed conservative specific effects different kinds agonists. activation mechanism was comparing conformational changes between inactive...
In an attempt to better understand factors contributing students’ off-task electronic multitasking behavior in class, the research included two studies that developed a scale of predictors (the SOTEMP scale), and explored relationships between various classroom communication processes outcomes. The first study inductively initial typologies for scale, refined item pool, dimensions scale. Subsequently, second validated through confirmatory factor analysis by assessing different concurrently...
Women with cancer often experience the risk of infertility and reproductive difficulties due to treatments. Social support is important for women understand manage challenges infertility. This study was designed explore both exchange social how negative expressed in two online discussion boards. Five types were studied: informational, emotional, appraisal, network, instrumental support. We used qualitative content analysis a directed coding scheme examine popular boards post-cancer...
Acculturation processes involve the development of language proficiency, cultural participation, and social relations. However, healthcare, an essential aspect people's life, is typically left out purview understanding acculturation process in academic literature. This study fills gap by examining domain healthcare among Asian migrants proposes a concept health acculturation. Based on qualitative interviews with U.S., this five-dimensional model encompassing literacy, beliefs attitudes,...