A5091482746- Gene Regulatory Network Analysis
- Algal biology and biofuel production
- Microbial Metabolic Engineering and Bioproduction
- Evolutionary Game Theory and Cooperation
- Evolution and Genetic Dynamics
- Phosphorus and nutrient management
- Mass Spectrometry Techniques and Applications
- Viral Infectious Diseases and Gene Expression in Insects
- Anaerobic Digestion and Biogas Production
- Biodiesel Production and Applications
- Graphene and Nanomaterials Applications
- biodegradable polymer synthesis and properties
- Global Socioeconomic and Political Dynamics
- Biofuel production and bioconversion
- Food Industry and Aquatic Biology
- Bone Tissue Engineering Materials
- 3D Printing in Biomedical Research
- Global Educational Reforms and Inequalities
- Higher Education Learning Practices
- Monoclonal and Polyclonal Antibodies Research
- Education Systems and Policy
- Wastewater Treatment and Nitrogen Removal
- Glycosylation and Glycoproteins Research
- Microbial Metabolites in Food Biotechnology
- Memory, Trauma, and Commemoration
University College London
2016-2024
University of London
2023
Universidad de Londres
2023
Biochemical Society
2019
Abstract The scope of bioengineering is expanding from the creation single strains to design microbial communities, allowing for division-of-labour, specialised sub-populations and interaction with “wild” microbiomes. However, in absence stabilising interactions, competition between microbes inevitably leads removal less fit community members over time. Here, we leverage amensalism competitive exclusion stabilise a two-strain by engineering strain Escherichia coli which secretes toxin...
The anaerobic digestion, AD, process presents a solution for sustainable waste management, greenhouse gas mitigation and energy production growing population needs requirements. Adopting biorefinery approach that utilises different feedstock may enhance support optimisation of the digestion process. Algae is promising could be used via Microalgal biomass rich in carbohydrates lipids; however, many species algae exhibit tough cell walls also difficult to digest influence or inhibit efficiency...
The clinical management of wounds is known to be a significant challenge: not only does the dressing need ensure and provide appropriate barrier healing characteristics, but consideration patient compliance concerning comfort, functionality, practicality also needs included. poly(3-hydroxybutyrate-
Off-gas analysis using a magnetic sector mass spectrometer was performed in mammalian cell cultures the fed-batch mode at 5 L bench and 50 pilot scales. Factors affecting MS gas traces were identified during duration of cultures. Correlation between viable concentration (VCC) oxygen inlet into bioreactor (O2-in) resulted R2 ≈ 0.9; O2-in could be used as proxy for VCC. Oxygen transfer (kLa) also quantified throughout culture period with antifoam addition different time points which is shown...
Abstract The scale of the biological systems we can engineer is limited by burden that host cells bear. Division-of-labour spread across a community but competitive exclusion inevitably leads to removal less fit members over time. Here, leverage amensalism and stabilise multi-species communities engineering strain Escherichia coli which secretes toxin in response competition. We show mathematically experimentally such system produce stable populations with composition tunable easily...
The department of Biochemical Engineering, UCL, is one the smallest departments in faculty Engineering Sciences, with an average annual intake approximately 40 undergraduate students on BEng/MEng programmes. Of that intake, around a third tend to be home and that, 40% identify as BAME (black ethnic minority). With