К.P. Luzhetskiy

ORCID: 0000-0003-0998-7465
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About
Contact & Profiles
Research Areas
  • Human Health and Disease
  • Healthcare Systems and Public Health
  • Thyroid Disorders and Treatments
  • Effects and risks of endocrine disrupting chemicals
  • Physical Education and Training Studies
  • Olfactory and Sensory Function Studies
  • Climate Change and Health Impacts
  • Vitamin D Research Studies
  • Mast cells and histamine
  • Science, Research, and Medicine
  • Nutrition, Genetics, and Disease
  • Health and Well-being Studies
  • Dye analysis and toxicity
  • Therapeutic Uses of Natural Elements
  • Chemical Reactions and Isotopes
  • Spaceflight effects on biology
  • Circadian rhythm and melatonin
  • Biomedical and Chemical Research
  • Cardiovascular Disease and Adiposity
  • Renal function and acid-base balance
  • thermodynamics and calorimetric analyses
  • Biomarkers in Disease Mechanisms
  • Technology and Human Factors in Education and Health
  • Health, Environment, Cognitive Aging
  • Air Quality and Health Impacts

Federal Scientific Center for Medical and Preventive Health Risk Management Technologies
2015-2024

Perm State University
2015-2017

We performed comparative sanitary-hygienic assessment of regime, stress and intensity educational process in different establishments, a comprehensive secondary school an innovative establishment -lyceum.We detected that studying regime tended to be tight, classes were longer more intense than ordinary school, involved considerable intellectual, sensory emotional loads for children; such reached "1st category intense" level.Schoolchildren attending lyceums are also busy with additional...

10.21668/health.risk/2017.1.08.eng article EN cc-by-nc Health Risk Analysis 2017-01-01

Проведена сравнительная санитарно-гигиеническая оценка режима, напряженности и интенсивности учебно-воспитательного процесса в образовательных учреждениях различного типа: средней общеобразовательной школе учебном заведении инновационного типалицее.Установлено, что для лицеев характерен уплотненный режим, большая продолжительность интенсивность занятий, а образовательный процесс сопряжен со значительными интеллектуальными, сенсорными эмоциональными нагрузками учащихся, достигающими уровня...

10.21668/health.risk/2017.1.08 article RU cc-by-nc Health Risk Analysis 2017-01-01

The article provides an individual risk assessment of metabolic disorders in the child population, consuming drinking water with elevated levels chloroform.Contingents children threatened by development are revealed, a variation serotonin receptor gene AG (HTR2A), increased susceptibility to oral exposure environmental organochlorines.It was found that HTR2A have content functionally associated this reduced 1.3 times blood serum, relative comparison group.Individual adverse effects...

10.21668/health.risk/2015.4.04.eng article EN cc-by-nc Health Risk Analysis 2015-04-01

Приводится оценка индивидуального риска метаболических нарушений у детского населения, потребляющего питьевую воду с повышенным содержанием хлороформа.Выявлены контингенты детей, угрожаемых по развитию нарушений, вариацией AG гена рецептора серотонина (HTR2A), имеющих повышенную чувствительность к внешнесредовой пероральной экспозиции хлорорганических соединений.Установлено, что дети HTR2A имеют пониженное (в 1,3 раза) содержание функционально связанного ним в сыворотке крови относительно...

10.21668/health.risk/2015.4.04 article RU cc-by-nc Health Risk Analysis 2015-04-01

Проведено исследование сезонной обеспеченности витаминами А, С, Д, Е, В 6 и 12 детей, посещающих дошкольные образовательные организации, осуществляющие стандартную искусственную витаминизацию рациона питания.Установлено, что у 75-85 % детей имеется круглогодичный дефицит витаминов, имеющий характер полигиповитаминоза 40 %.В осенне-зимний период обеспеченность соответствует физиологическим потребностям, однако в весенние месяцы 70 испытывают витамина а 15 %витамина А. Даже осенний каждый...

10.21668/health.risk/2015.4.10 article RU cc-by-nc Health Risk Analysis 2015-04-01

There was executed a clinical laboratory study of 183 children residing in the conditions constant low-level impact complex such consumed from atmospheric air and drinking water metals as lead, manganese, nickel, chrome, cadmium) 46 sanitary-hygienically wellbeing habitat. The evaluation Total Hazard Indices (THI) for chemical substances entering with have revealed excess accepted values (THI>1) regarding to disorders central nervous system (THI amounted up 4.93) ofendocrine (up THI...

10.18821/0016-9900-2017-96-1-70-75 article EN Hygiene and Sanitation 2019-03-27

Introduction. Within the Demography National Project, Federal Service for Supervision in Protection of Rights Consumer and Man Wellbeing (Rospotrebnadzor) performs specific activities aimed at creating an environment that raises people’s awareness about health diets. The number people who have been educated on matter represented index key performance, unfortunately, it does not show whether any socially significant results achieved, first all, concerning protection. aim this study is to...

10.47470/0016-9900-2024-103-11-1368-1375 article EN Hygiene and Sanitation 2024-12-16

The comparative assessment of immune profile indicators in children under = benzo(a)pyrene and cold factor influence a case-control study with the modeling verification obtained results an vivo experiment was performed. In course airborne exposure signs phagocytic leukocyte activity inhibition specific haptenic hypersensitivity formation (IgG to benzo(a)pyrene) associated blood contamination were established. Revealed changes xenobial biomedia composition at dose 0.00761 mcg/(kg*day)...

10.25789/ymj.2024.88.15 article EN Yakut Medical Journal 2024-12-30

Chemical environmental factors trophic for the endocrine system and its organs produce negative influence on it that becomes apparent through growing incidence pathomorphism of diseases. Our test group was made up 102 children with diagnosed autoimmune thyroiditis (AIT) who were chronically exposed to metals (lead, manganese, nickel, chromium, zinc) being components in emissions from metallurgic enterprises Perm region. reference included 46 AIT lived beyond zones influenced by...

10.21668/health.risk/2021.4.06 article EN cc-by-nc Health Risk Analysis 2021-12-01

This paper deals with study of the seasonal vitamin provision for 188 organized children attending pre-school educational institutions standard main meal C-fortification. The showed that 75–85 % have year-round deficiency, 40 whom it in nature polyhypo-vitaminosis. has shown even autumn-winter period basic does not exceed lower bound physiological norm, and during spring months about 70 per cent suffer from subclinical C deficiency 15 A de-ficiency. While every third child a B6 10 D...

10.35627/2219-5238/2018-305-8-59-64 article EN cc-by-nc ЗДОРОВЬЕ НАСЕЛЕНИЯ И СРЕДА ОБИТАНИЯ - ЗНиСО / PUBLIC HEALTH AND LIFE ENVIRONMENT 2018-08-01

The study focuses on pathogenesis of chronic gastroduodenal diseases in children caused by low quality drinking water containing hyperchlorination products (chloroform) and manganese.It was determined that the clinical manifestation pathological process with a higher level manganese chloroform blood is conjugated development parasympathetic-type vegetative disfunction, reactive changes liver tissue, hypomotor-type biliary hyperkinetic-type gastric duodenal motor activity...

10.21668/health.risk/2014.3.08.eng article EN cc-by-nc Health Risk Analysis 2014-03-01

A study of the seasonal provision children attending pre-school organizations that implement standard artificial diet fortification with vitamins A, C, D, E, В6 and B12 was performed.It found 75-85 % have a yearround vitamin deficiency 40 cases status polyhypovitaminose.In autumn winter corresponds to physiological needs, but in spring months 70 deficit 15 -in A. Even autumn, every third child has B6, tenth D; number insufficient these increases 1.8-6.3times.Half children, who attend...

10.21668/health.risk/2015.4.10.eng article EN cc-by-nc Health Risk Analysis 2015-04-01

Chemical environmental factors trophic for the endocrine system and its organs produce negative influence on it that becomes apparent through growing incidence pathomorphism of diseases. Our test group was made up 102 children with diagnosed autoimmune thyroiditis (AIT) who were chronically exposed to metals (lead, manganese, nickel, chromium, zinc) being components in emissions from metallurgic enterprises Perm region. reference included 46 AIT lived beyond zones influenced by...

10.21668/health.risk/2021.4.06.eng article EN cc-by-nc Health Risk Analysis 2021-12-01

Introduction. Formaldehyde is a widespread environmental contaminant hazardous for human health; it belongs to the second hazard category its inhalation exposure. Aerogenic exposure results in elevated risks of adverse effects on health. Children are susceptible such produced by formaldehyde. Materials and methods. We performed chemical-analytical studies formaldehyde contents ambient air, inside pre-school children facilities schools, biological media living large industrial city (the test...

10.47470/0016-9900-2022-101-2-194-200 article EN Hygiene and Sanitation 2022-03-10

Introduction. The authors performed a hygienic and epidemiological study of the Perm Territory areas with unfavorable sanitary indices. Material methods. involved 7,775 children aged from 4 to 14 years (9.2 ± 3.7 years) living in territories using sodium hypochlorite or liquid chlorine (Perm, Krasnokamsky, Nytvensky districts). comparison group consisted 425 (average age 9.3 2.5 consuming drinking water that complies standards (Sivinsky, Karagai Results. Identified low quality supply due...

10.47470/0016-9900-2020-99-11-1263-1270 article EN Hygiene and Sanitation 2020-12-22

Introduction. Working conditions, clinical and laboratory status of 236 workers a chromium mine were investigated. Materials methods. The observation group included 162 underground employees working in conditions the combined impact negative occupational factors (dust, noise, vibration, tension severity there, cooling microclimate) - class 3.3-3.4. comparison 74 acceptable 2. Results. In group, pathology cardiovascular endocrine system (ICD-10: I00-I99, E00-E07) was detected 2.8-3.3 times...

10.47470/0016-9900-2021-100-10-1095-1102 article EN Hygiene and Sanitation 2021-10-31

Исследованы патогенетические механизмы развития у детей хронических гастродуоденальных заболеваний, обусловленных потреблением питьевой воды ненадлежащего качества по содержанию продуктов гиперхлорирования (хлороформ) и марганца.Установлено, что клиническая манифестация патологического процесса с повышенным содержанием марганца хлороформа в крови сопряжена развитием вегетативных дисфункций парасимпатическому типу, реактивных изменений ткани печени, билиарной дисфункции гипомоторному...

10.21668/health.risk/2014.3.08 article RU cc-by-nc Health Risk Analysis 2014-03-01

The problem of assessing the impact disorders lipid metabolism on cardiovascular risk remains relevant.
 Purpose study: to study relationship between thickness abdominal adipose tissue and parameters blood profile in young women. 
 Materials methods. Two hundred four women (36.4 ± 5.4 years) were examined. Body mass index (BMI), waist circumference (WC), as well ultrasonic criteria for (subcutaneous preperitoneal thickness, circumference), spectrum assessed, was calculated....

10.47470/0044-197x-2023-67-6-502-509 article EN Health Care of the Russian Federation 2023-12-23

Peculiarities of physical development disorders in 334 children were examined the course comparative clinical-laboratory research; all these consumed drinking water with various nitrates content (11.2±1.1 mg/l and up to 3.14 MPC, i.e. 141 mg/l), a dose equal 9.0 mg/kg body weight (RfD 1.6 mg/kg). A focus group consisted 158 aged from 3 10, control was made 176 same age. Nitrates urine taken (49.22±11.69 mg/l) 2.4 fold higher than parameter (20.2±3.13 mg/l, р=0,001). Under exposure endocrine...

10.24411/0042-8833-2017-00043 article EN PubMed 2017-01-01

The biological characteristics of the organism, including genetic status, can be taken as indices individual susceptibility. These susceptibility applied in health risk assessment if there is shown probability development disorders induced by exposure to environmental factors and their cause-and-effect relationship with these proved. To distinguish values formation conditions occupational it proposed perform consecutive identification contingents, probable effects; evaluation factors, use...

10.18821/0016-9900-2018-97-4-369-374 article EN Hygiene and Sanitation 2018-04-15
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