A5068125449- Tryptophan and brain disorders
- Cholinesterase and Neurodegenerative Diseases
- Gut microbiota and health
- Advancements in Transdermal Drug Delivery
- Essential Oils and Antimicrobial Activity
- Epigenetics and DNA Methylation
- Dermatology and Skin Diseases
- Neuroscience and Neuropharmacology Research
- Biochemical effects in animals
- Advanced Drug Delivery Systems
- COVID-19 Clinical Research Studies
- Phytochemicals and Antioxidant Activities
- SARS-CoV-2 and COVID-19 Research
- Computational Drug Discovery Methods
- Synthesis and biological activity
- Olfactory and Sensory Function Studies
- Long-Term Effects of COVID-19
- Phytochemistry and Biological Activities
- Medicinal Plant Research
- Phytochemicals and Medicinal Plants
- Flavonoids in Medical Research
- Phytochemistry and biological activity of medicinal plants
- Genetic and Kidney Cyst Diseases
- Cancer Treatment and Pharmacology
- Parkinson's Disease Mechanisms and Treatments
Shoolini University
2020-2025
University of Technology Sydney
2024
Bridge University
2024
International Medical University
2024
Management Sciences (United States)
2024
Jaypee University of Information Technology
2014-2017
Armed Forces Medical College
2014
S Nijalingappa Medical College and HSK Hospital & Research Centre
2009
The vitreous humor is a transparent, gelatinous mass whose main constituent water. It plays an important role in providing metabolic nutrient requirements of the lens, coordinating eye growth and support to retina. close proximity retina reflects many changes occurring this tissue. biochemical could provide better understanding about pathophysiological processes that occur vitreoretinopathy. In study, we investigated proteome normal human using high resolution Fourier transform...
Acetylcholinesterase (AChE) is one of the key enzyme targets that have been used clinically for management Alzheimer's Disorder (AD). Numerous reports in literature predict and demonstrate in-vitro, in-silico anticholinergic activity herbal molecules, however, majority them failed to find clinical application. To address these issues, we developed a 2D-QSAR model could efficiently AChE inhibitory molecules along with predicting their potential cross blood-brain-barrier (BBB) exert beneficial...
Diabetic neuropathy is a chronic and often disabling condition that affects significant number of individuals with diabetes mellitus (DM). It now established DM causes various CNS complications like Alzheimer's, dementia, anxiety, depression, neurodegeneration, mood disorders, cognitive dysfunctioning, so on. Since amygdala dopaminergic circuitry are critical in controlling several aspects social behavior, even recognition memory (SRM), we aimed to study the expression analysis using...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2 or COVID-19), outbreak was first reported in December 2019 the Wuhan, China. COVID-19 managed to spread worldwide and so far more than 9.1 million cases 4.7 lakh death has been globally. Children, pregnant women, elderly population, immunocompromised patients, patients with conditions like asthma, diabetes, etc. are highly vulnerable COVID infection. Currently, there is no treatment available for Traditional medicinal plants have...
<b>Objective:</b> To develop an amino acid prodrug of acetaminophen with comparable therapeutic profile and less hepatotoxicity than acetaminophen.<br> <b>Materials Methods:</b> Acetaminophen was synthesized by esterification between the carboxyl group glycine hydroxyl acetaminophen. Analgesic, antipyretic, ulcer healing, hepatotoxic activities were performed on Wistar rats in this study.<br> <b>Results:</b> Prodrug showed a 44% inhibition writhings as compared to 53.3% also offered highest...
<p><strong>Objective: </strong>Aim of the present study was to formulate solid lipid nanoparticles (SLNs) and determine their physicochemical parameters when stored at cold temperature in aqueous solution (D-SLNs) prior biological application.<strong></strong></p><p><strong>Methods: </strong>SLNs were formulated though nanoprecipitation technique which comprised stearic acid (lipid), poloxamer 188 lecithin (surfactant). Physicochemical...
Abstract Acetylcholinesterase (AChE) is one of the key enzyme targets that have been used clinically for management Alzheimer’s Disorder (AD). Numerous reports in literature predict and demonstrate in-vitro , in-silico anticholinergic activity synthetic herbal molecules, however, majority them failed to reproduce results preclinical or clinical settings. To address these issues, we developed a 2D-QSAR model could not only efficiently AChE inhibitory molecules but also predicted their...
<title>Abstract</title> Purpose Vaginal candidiasis (VC), a common recurrent gynaecological disorder affects almost 70% women. Development of resistance to antifungal agents exacerbates the need for new treatments against <italic>Candida</italic> infections. The objective current work was develop Ethosomal Vesicles (EVs) and EV hydrogel Butea monosperma seed oil (BMSO) treatment vaginal as BMSO has demonstrated fungicidal bactericidal activity. Methods EVs, formulated by ethanol...