- Oral microbiology and periodontitis research
- Oral Health Pathology and Treatment
- Dental Health and Care Utilization
- Periodontal Regeneration and Treatments
- Oral and Maxillofacial Pathology
- Salivary Gland Disorders and Functions
- Oral and gingival health research
- Dental Implant Techniques and Outcomes
- Orthodontics and Dentofacial Orthopedics
- Dental Anxiety and Anesthesia Techniques
- Dental Radiography and Imaging
- Bone Tissue Engineering Materials
- Streptococcal Infections and Treatments
- Dental Research and COVID-19
- Temporomandibular Joint Disorders
- Endodontics and Root Canal Treatments
- HIV/AIDS oral health manifestations
- MicroRNA in disease regulation
- Cancer and Skin Lesions
- Tumors and Oncological Cases
- Cancer-related molecular mechanisms research
- Advanced Drug Delivery Systems
- Mast cells and histamine
- Autoimmune and Inflammatory Disorders Research
- Mesenchymal stem cell research
University of Catania
2019-2025
University of Messina
2024-2025
Abstract Aim This study evaluated the efficacy of quadrantwise subgingival instrumentation (Q‐SI) versus one‐stage full‐mouth (FM‐SI) on probing depth and periodontal pathogen reduction over a 6‐month follow‐up period, as well whether baseline pathogens influenced impact treatment protocols outcomes. Methods Patients with periodontitis were randomized to receive Q‐SI ( n = 43) or FM‐SI 45). instructed motivated maintain optimal oral hygiene during sessions. Clinical (probing pocket [PPD],...
Nod-like receptor family pyrin domain-containing protein-3 (NLRP3) complex inflammasome has potentially been shown to play an important role in the development of periodontitis and diabetes. The objective this study was analyze association between serum salivary NLRP3 concentrations patients with type-II diabetes mellitus (DM) evaluate whether influenced by potential confounders.For present study, a cohort healthy controls (n = 32), 34), DM 33), combination + 34) were enrolled. Patients...
Malondialdehyde (MAA) within a lipid pathway has been demonstrated to possess an important role in endothelial function that undergoes periodontitis and coronary heart disease (CHD) development. This study evaluated the impact of periodontitis, CHD, or combination both diseases (periodontitis + CHD) on salivary serum MAA levels. The periodontal clinical characteristics, serum, saliva samples were collected from 32 healthy subjects, 34 patients with 33 CHD. Lipid profile levels MDA C-reactive...
Abstract Background and Objective Recent emerging evidence has shown that microRNA (miRNAs) is involved in several epigenetic processes linked with periodontitis, increased oxidative stress cardiovascular disease (CVD). The present study aimed to assess the impact of periodontitis on gingival crevicular fluid (GCF) miRNAs expression associated CVD risk evaluate possible confounders influenced this association. Materials Methods For study, healthy controls ( n = 28) subjects 28), 30) + 29)...
N-terminal portion of the B-type natriuretic propeptide (NT-proBNP) has potentially been shown to play an important role in development periodontitis and cardiovascular disease (CVD). This study evaluated efficacy periodontal treatment on NT-proBNP related CVD biomarkers explored whether subjects harboring high at baseline showed increased clinical benefits with non-surgical performed full-mouth scaling root planing (FM-SRP) 6-month follow-up.
The regeneration of periodontal bone defects continues to be an essential therapeutic concern in dental biomaterials. Numerous biomaterials have been utilized this sector so far. However, the immune response and vascularity defect regions may disregarded when evaluating effectiveness for repair. Among several regenerative treatments, most recent technique situ tissue engineering stands out its ability replicate endogenous restorative processes by combining scaffold with particular growth...
To evaluate the effectiveness of two different therapies on oral lichen planus (OLP) treatment through analysis OLP symptoms and signs to analyze risk side effects related adopted protocols.Thirty-eight patients with were selected according van der Meij Waal clinical histopathological criteria. Through a randomized design, 19 received Tacrolimus 0.1% ointment (T group) an anti-inflammatory mouthwash (M composed calcium hydroxide 10%, hyaluronic acid 0.3%, umbelliferone, oligomeric...
Abstract Background During the last decades, in patients with periodontitis, periodontal treatment has been shown to reduce potential release of local and systemic biomarkers linked an early risk inflammatory disorders. This study evaluated efficacy non-surgical-periodontal (NSPT) on growth differentiation factor 15 (GDF-15) related circulating such as glutathione peroxidase 1 (GPx-1), c-reactive protein (hs-CRP), surfactant D (SP-D) explored whether subjects who had high GDF-15 levels at...