A5044426069- Tuberous Sclerosis Complex Research
- Acute Ischemic Stroke Management
- Blood Coagulation and Thrombosis Mechanisms
- Cerebral Venous Sinus Thrombosis
- Neurological Complications and Syndromes
- Histiocytic Disorders and Treatments
- Epilepsy research and treatment
- Neurology and Historical Studies
- Tumors and Oncological Cases
- Neurological and metabolic disorders
- Cerebrovascular and Carotid Artery Diseases
- Moyamoya disease diagnosis and treatment
- Metabolism and Genetic Disorders
- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
- Polyomavirus and related diseases
- Hemoglobinopathies and Related Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations and Hemangiomas
- Neurofibromatosis and Schwannoma Cases
- Connective tissue disorders research
- Fetal and Pediatric Neurological Disorders
- Vascular Malformations Diagnosis and Treatment
- Folate and B Vitamins Research
- Cerebrovascular and genetic disorders
The University of Texas at Austin
2018-2025
Grady Memorial Hospital
2025
Huntsman Cancer Institute
2023
University of Utah
2023
Dell Children's Medical Center of Central Texas
2020-2023
The Ohio State University
2008-2018
Nationwide Children's Hospital
2010-2018
Research Network (United States)
2018
Icahn School of Medicine at Mount Sinai
2017
Columbus State Community College
2017
Purpose- Much has transpired since the last scientific statement on pediatric stroke was published 10 years ago. Although long been recognized as an adult health problem causing substantial morbidity and mortality, it is also important cause of acquired brain injury in young patients, occurring most commonly neonate throughout childhood. This represents a synthesis data consensus leading experts childhood cardiovascular disease stroke. Methods- Members writing group were appointed by...
No AccessJournal of UrologyPediatric Urology1 Jul 1998RENAL LESION GROWTH IN CHILDREN WITH TUBEROUS SCLEROSIS COMPLEX DAVID H. EWALT, EUGENE SHEFFIELD, STEVEN P. SPARAGANA, MAURICIO R. DELGADO, and E. STEVE ROACH EWALTDAVID EWALT , SHEFFIELDEUGENE SHEFFIELD SPARAGANASTEVEN SPARAGANA DELGADOMAURICIO DELGADO ROACHE. View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)63072-6AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints...
Tuberous sclerosis complex is an autosomal dominant disorder predisposing to the development of benign lesions in different body organs, mainly brain, kidney, liver, skin, heart, and lung. Subependymal giant cell astrocytomas are characteristic brain tumors that occur 10% 20% tuberous patients almost exclusively related complex. usually grow slowly, but their progression ultimately leads occlusion foramen Monro, with subsequent increased intracranial pressure hydrocephalus, thus...
This study presents a large multicenter cohort of children with cerebral venous thrombosis from 5 centers in the United States and analyzes their clinical findings risk factors. Seventy patients were included (25 neonates, 35%). The age ranged 6 days to 12 years. Thirty-eight (55%) younger than months age, 28 (40%) male. Presenting features seizures (59%), coma (30%), headache (18%), motor weakness (21%). Common neurological decreased level consciousness (50%), papilledema cranial nerve...
Background and Purpose— The implementation of uniform nomenclature classification in adult arterial ischemic stroke (AIS) has been critical for defining outcomes recurrence risks according to etiology developing risk-stratified treatments. In contrast, current childhood AIS are often overlapping or contradictory. Our purpose was develop a comprehensive consensus-based system AIS. Methods— Using modified-Delphi method, members the International Pediatric Stroke Study (IPSS) developed...
The clinical and radiographic findings of 68 children adolescents with nontraumatic intraparenchymal brain hemorrhage were analyzed retrospectively. There 43 boys 25 girls, the average age was 7.1 years (range, 3 months to 18 years). most common presenting symptom a combination headache or vomiting (40 cases, 58.8%). Hemiparesis major sign in 11 (16.2%) children, seizures occurred (36.8%) patients, 6 (8.8%) irritable. Only 2 (2.9%) comatose at presentation. One more risk factors for found 61...
Twenty-five patients with tuberous sclerosis were studied magnetic resonance imaging (MRI), and these findings compared those of computed cranial tomography (CCT) the clinical severity disease. Multiple high-signal MRI lesions involving cerebral cortex are characteristic probably correspond to hamartomas gliotic areas seen pathologically. These cortical only occasionally CCT. The periventricular calcific better visualized CCT than MRI, but larger calcifications produce low-signal...
No AccessJournal of UrologyAdult Urology: Oncology: Adrenal/Renal/Upper Tract/Bladder1 Nov 2005LONG-TERM OUTCOME OF TRANSCATHETER EMBOLIZATION RENAL ANGIOMYOLIPOMAS DUE TO TUBEROUS SCLEROSIS COMPLEX DAVID H. EWALT, NORMAN DIAMOND, CHET REES, STEVEN P. SPARAGANA, MAURICIO DELGADO, LORI BATCHELOR, and E. STEVE ROACH EWALTDAVID EWALT , DIAMONDNORMAN DIAMOND REESCHET REES SPARAGANASTEVEN SPARAGANA DELGADOMAURICIO DELGADO BATCHELORLORI BATCHELOR ROACHE. View All Author...
Nontraumatic intracranial hemorrhages (ICHs) are uncommon in children, but important causes of death and injury.To determine whether the risk factors for ICH have changed compared with those earlier published series to estimate residual deficits survivors.We performed a retrospective review patients admitted single tertiary care, academic pediatric hospital from January 1, 2000, through May 31, 2007. Records were retrieved if diagnostic codes International Classification Diseases, Ninth...
<b><i>Objective:</i></b> To clinically characterize affected individuals in families with paroxysmal kinesigenic dyskinesia (PKD), examine the association infantile convulsions, and confirm linkage to a pericentromeric chromosome 16 locus. <b><i>Background:</i></b> PKD is characterized by frequent, recurrent attacks of involuntary movement or posturing response sudden movement, stress, excitement. Recently, an autosomal dominant locus on was identified. <b><i>Methods:</i></b> The authors...
We present 19 patients with tuberous sclerosis complex and subependymal giant cell astrocytoma. The mean age at the time of tumor diagnosis was 9.4 years (range, 1.5 to 21 years). Computed cranial tomography (CT) or magnetic resonance imaging (MRI) identified lesion which resected in all cases. Seven had hydrocephalus there an interval increase size a large without 12 patients. Surgical criteria included: (1) presence hydrocephalus; (2) size; (3) new focal neurologic deficit attributable...