Lai-Ping Wong

ORCID: 0000-0003-1025-8833
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About
Contact & Profiles
Research Areas
  • Epigenetics and DNA Methylation
  • Circadian rhythm and melatonin
  • Immune Cell Function and Interaction

Harvard University
2022

Massachusetts General Hospital
2022

A sleepless night may feel awful in its aftermath, but sleep's revitalizing powers are substantial, perpetuating the idea that convalescent sleep is a consequence-free physiological reset. Although recent studies have shown catch-up insufficiently neutralizes negative effects of debt, mechanisms control prolonged disruption not understood. Here, we show interruption restructures epigenome hematopoietic stem and progenitor cells (HSPCs) increases their proliferation, thus reducing clonal...

10.1084/jem.20220081 article EN cc-by-nc-sa The Journal of Experimental Medicine 2022-09-21
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