A5090619670- Electric Motor Design and Analysis
- Magnetic Bearings and Levitation Dynamics
- Induction Heating and Inverter Technology
- Magnetic Properties and Applications
- Psoriasis: Treatment and Pathogenesis
- Sensorless Control of Electric Motors
- Advanced Welding Techniques Analysis
- Immunotherapy and Immune Responses
- Wireless Power Transfer Systems
- Electromagnetic Launch and Propulsion Technology
- Dermatology and Skin Diseases
- Cytokine Signaling Pathways and Interactions
- Hydrocarbon exploration and reservoir analysis
- Engineering Applied Research
- Graphene research and applications
- Immune Cell Function and Interaction
- Immune cells in cancer
- Metallurgy and Material Forming
- Mesenchymal stem cell research
- Atmospheric and Environmental Gas Dynamics
- Urticaria and Related Conditions
- Coal Properties and Utilization
- T-cell and B-cell Immunology
- Mast cells and histamine
- Aluminum Alloy Microstructure Properties
Shenyang University of Technology
2011-2025
Shanghai Jiao Tong University
2015-2024
Chengdu University of Technology
2024
State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation
2024
Shanghai First People's Hospital
2018-2024
Shanghai Clinical Research Center
2022-2024
Kyungsung University
2011-2023
Chinese Academy of Sciences
2012-2023
Shenyang Institute of Automation
2018-2023
Shanghai Institute of Hematology
2014-2021
Abstract NF-κB is constitutively activated in psoriatic epidermis. However, how promotes keratinocyte hyperproliferation psoriasis largely unknown. Here we report that the activation triggered by inflammatory cytokines induces transcription of microRNA (miRNA) miR-31, one most dynamic miRNAs identified skin patients and mouse models. The genetic deficiency miR-31 keratinocytes inhibits their hyperproliferation, decreases acanthosis reduces disease severity Furthermore, protein phosphatase 6...
Many annotated long noncoding RNAs (lncRNAs) harbor predicted short open reading frames (sORFs), but the coding capacities of these sORFs and functions resulting micropeptides remain elusive. Here, we report that human lncRNA MIR155HG encodes a 17-amino acid micropeptide, which termed miPEP155 (P155). is highly expressed by inflamed antigen-presenting cells, leading to discovery P155 interacts with adenosine 5'-triphosphate binding domain heat shock cognate protein 70 (HSC70), chaperone...
Abstract Dermal fibroblasts and cutaneous nerves are important players in skin diseases, while their reciprocal roles during inflammation have not been characterized. Here we identify an inflammation-induced subset of papillary that promotes aberrant neurite outgrowth psoriasiform by secreting the extracellular matrix protein tenascin-C (TNC). Single-cell analysis fibroblast lineages reveals a Tnc + with pro-axonogenesis neuro-regulation transcriptomic hallmarks. TNC overexpression boosts...
Abstract Peripherally derived regulatory T (pT reg ) cell generation requires T-cell receptor (TCR) signalling and the cytokines TGF-β1 IL-2. Here we show that TCR induces microRNA miR-31, which negatively regulates pT -cell generation. miR-31 conditional deletion results in enhanced induction of cells, decreased severity experimental autoimmune encephalomyelitis (EAE). Unexpectedly, identify Gprc5a as a direct target miR-31. is known retinoic acid-inducible protein 3, its deficiency leads...
The monocyte/macrophage system plays an essential role in the host response and fate of endosseous implanted materials. Macrophage behavior was thought to be regulated by nanostructured titanium which has been considered as a very promising candidate for dental implants. However, there is little known subsequent effects these activated macrophages on osteogenesis angiogenesis were bone integration. Here we presented two different dimensions nanotubes generated anodic oxidation at 10 V (NT...
Abstract In this paper, the thermodynamic characteristics, magnetocaloric effect and ground-state properties of an edge-decorated Ising multilayer nanoparticle with graphene-like structure are studied by Monte Carlo simulation. The results reveal that size effect, crystal field, exchange coupling, applied magnetic field can control behaviors system. addition, curves entropy change relative cooling power (RCP) given induced various physical parameters.
In order to solve the issues concerning high hot tearing susceptibility (HTS) of Mg-Al-Ca series alloys, a rotating magnetic field (RMF) was applied during their solidification. The effect RMF at different excitation current intensities (50 A, 100 and 150 A) on solidification behavior AXJ530 (Mg-5Al-3Ca-0.17Sr) alloy investigated. results indicated that HTS decreased with increase intensity. This aspect can be attributed significant grain refinement under action RMF, which improved...
Abstract Psoriasis is a chronic recurrent inflammatory skin disorder characterized by the dysregulated cross-talk between epidermal keratinocytes and immune cells, leading to keratinocyte hyperproliferation. Several studies demonstrated that Wnt pathway genes were differentially expressed in psoriatic plaques likely involved pathophysiology of disease. However, molecular mechanisms underlying signaling regulation hyperplasia psoriasis remain largely unknown. We report expression secreted...
Research Article4 April 2017Open Access Source DataTransparent process RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease Huiyuan Zhu Key Laboratory of Cell Differentiation Apoptosis Chinese Ministry Education, Department Immunology Microbiology, Shanghai Institute Immunology, Jiao Tong University School Medicine (SJTU-SM), Shanghai, China Search for more papers by this author Fangzhou Lou Qianqian Yin Yuanyuan Gao Yang Sun Jing Bai Zhenyao Xu Zhaoyuan...
This paper presents a novel 6/5 segmental rotor-type switched reluctance motor (SRM) for cooling fan application. Unlike conventional structures, the rotor of proposed structure is constructed from series discrete segments, and stator two types poles: exciting auxiliary poles. Meanwhile, windings are only placed around poles, resulting in short flux paths no reversal SRM. Hence, may increase electrical utilization reduce magnetomotive force (MMF) requirement compared to SRMs. To verify...
In this paper, three types of bearingless switched reluctance motors (BLSRMs) which have decoupled flux characteristics between the torque and suspending current are presented in detail. The analyzed BLSRMs an 8/10 hybrid BLSRM, a 12/14 double stator BLSRM. BLSRM has low electrical frequency with decoupling characteristics. short path to reduce core loss higher best complex mechanical structure. All structures two poles: force poles. Due independent poles, control can be from control. types,...
Melanoma is a life-threatening cancer with limited treatments. Retinoic acid-inducible gene I (RIG-I) cytosolic pattern recognition receptor (PRR) crucial to RNA virus sensing, interferon production, and tumor suppression. Quercetin, natural flavonoid, has particularly therapeutic interests prevent treat cancer, for its pharmacological effects against oxidant, inflammation, angiogenesis. Quercetin was investigated anti-melanoma activity potential mechanisms in this study. We found that...
ABSTRACT Heat pipe is a kind of heat transfer element with very high thermal conductivity, which has good application prospect in power density driving motors. However, the complicated process involves variety mechanisms, undoubtedly increases difficulty temperature field modelling. Therefore, equivalent conductivity model flat (FHP) considering influence some factors was established. First, mathematical can fully consider thickness shell, vapour chamber, length endothermic section and...
Graphdiyne-like nanoribbons are promising for information retrieval, storage, and magnetic refrigeration due to their excellent thermodynamic properties. In this paper, we build a ferrimagnetic mixed-spin (2, 5/2) Ising model the bilayer graphdiyne-like nanoribbon. The instantaneous magnetization, dynamic order parameter, susceptibility, phase diagram, hysteresis loops studied induced by exchange coupling, crystal field, amplitude period of time-oscillating field [Formula: see text]....