A5041361476- Autoimmune Bullous Skin Diseases
- Ethics in Clinical Research
- Biomedical Ethics and Regulation
- Urticaria and Related Conditions
- Genomics and Rare Diseases
- BRCA gene mutations in cancer
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Skin and Cellular Biology Research
- Ethics in medical practice
- Cardiac, Anesthesia and Surgical Outcomes
- Prenatal Screening and Diagnostics
- Pelvic floor disorders treatments
- Medieval Literature and History
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Dermatological and Skeletal Disorders
- Race, Genetics, and Society
- Nitric Oxide and Endothelin Effects
- Geriatric Care and Nursing Homes
- Ethics and Legal Issues in Pediatric Healthcare
- Palliative Care and End-of-Life Issues
- Autism Spectrum Disorder Research
- Neonatal Respiratory Health Research
- Misinformation and Its Impacts
- Dermatology and Skin Diseases
University of Exeter
2012-2023
Lincoln Agritech (New Zealand)
2023
Lincoln University
2023
Shrewsbury and Telford Hospital NHS Trust
2019-2023
Carl Zeiss (United States)
2023
E Ink (South Korea)
2022
Royal Shrewsbury Hospital
2009-2020
University of Wisconsin–La Crosse
2017-2019
Age UK
2016
Genomics (United Kingdom)
2008-2014
To assess the relationship between body temperature and cardiac morbidity during perioperative period.Randomized controlled trial comparing routine thermal care (hypothermic group) to additional supplemental warming (normothermic group).Operating rooms surgical intensive unit at an academic medical center.Three hundred patients undergoing abdominal, thoracic, or vascular procedures who either had documented coronary artery disease were high risk for disease.The relative of a morbid event...
Journal Article Psoriasis‐an index of disability Get access A. Y. FINLAY, FINLAY Department Dermatology, Southern General Hospital, Glasgow GSI 4TF, Scotland Dr Finlay, G51 Scotland. Search for other works by this author on: Oxford Academic Google Scholar S. E. KELLY Clinical and Experimental Volume 12, Issue 1, 1 January 1987, Pages 8–11, https://doi.org/10.1111/j.1365-2230.1987.tb01844.x Published: 01 1987 history Accepted: 07 July 1986
The dominant, individualistic understanding of autonomy that features in clinical practice and research is underpinned by the idea people are, their ideal form, independent, self-interested rational gain-maximising decision-makers. In recent decades, this paradigm has been challenged from various disciplinary intellectual directions. Proponents 'relational autonomy' particular have argued people's identities, needs, interests - indeed are always also shaped relations to others. Yet, despite...
FRANK, S. M.; FLEISHER, L. A.; BRESLOW, M. J.; HIGGINS, S.; OLSON, K. F.; KELLY, BEATTIE, C.; McGoldrick, Kathryn E. M.D. Author Information
We identified psychosocial, structural, and cultural barriers to seeking dental care among nonutilizing caregivers of Medicaid-enrolled children.We used Medicaid utilization records identify utilizing African American White children in Jefferson County, Kentucky. conducted 8 focus groups (N=76) with a stratified random sample responding caregivers; transcripts were qualitatively analyzed.Psychosocial factors associated included oral health beliefs, norms caregiver responsibility, positive...
Human skin and mucous membranes were used to detect circulating auto-antibodies by indirect immunofluorescence in 20 patients with bullous pemphigoid eight cicatricial pemphigoid. The tissue substrate was intact after chemical separation through the basement membrane zone (BMZ) incubation I M NaCl. Chemically split oral mucosa provided a more sensitive assay for demonstrating anti BMZ antibodies. Use of battery substrates increased number positives from 30% detected on monkey oesophagus 100%...
Background Studies throughout Northern Europe, the United States and Australia have found an association between childhood attention deficit hyperactivity disorder ( ADHD ) family socioeconomic disadvantage. We report further evidence for review potential causal pathways that might explain link. Method Secondary analysis of a UK birth cohort (the Millennium Cohort Study, N = 19,519) was used to model with disadvantage assess several explanatory pathways. The case definition parent‐report...
Technological advances have increased the availability of genomic data in research and clinic. If, over time, interpretation significance changes, or new information becomes available, question arises as to whether recontacting patient and/or family is indicated. The Public Professional Policy Committee European Society Human Genetics (ESHG), together with groups from UK Netherlands, developed recommendations on which, after public consultation, been endorsed by ESHG Board. In clinical...
Background — In healthy humans, continuous treatment with nitroglycerin (GTN) causes nitric oxide synthase dysfunction, probably through the reduced bioavailability of tetrahydrobiopterin. Recent studies proposed that folic acid is involved in regeneration tetrahydrobiopterin different disease states. Therefore, we investigated whether administration would prevent this phenomenon. We also sought to determine if supplementation could development tolerance GTN. Methods and Results On first...
No AccessJournal of UrologyUrological Survey: Abstracts: Perioperative Care1 Jul 1998Perioperative Maintenance Normothermia Reduces the Incidence Morbid Cardiac Events. A Randomized Clinical Trial S.M. Frank, L.A. Fleisher, M.J. Breslow, M.S. Higgins, K.F. Olson, S. Kelly, and C. Beattie FrankS.M. Frank More articles by this author , FleisherL.A. Fleisher BreslowM.J. Breslow HigginsM.S. Higgins OlsonK.F. Olson KellyS. Kelly BeattieC. View All Author...
Scientists are racing to unravel the code of life in our DNA sequences. But once we know code, will what means? Will do with powerful information have? Barbara Katz Rothman examines current trends and applications genetics research on race, illness procreation. She explores new light her work as a sociologist who has studied motherhood women's experiences prenatal genetic testing, participation world bioethical discussions genetics, personal mother an interracial family. Her book aims help...
Parents of children with genetic conditions or impairments stand in a unique position regard to choices and dilemmas posed by prenatal screening testing options offered at-risk parents as means 'healthy' baby. This article reports the results qualitative study whose are clients state-wide rural outreach programme US. The analysis seeks connect lived experience which women confronted technologies continue proliferate. It finding that majority chose not choose: avoiding future pregnancies,...
<i>Background/Objectives:</i> Non-invasive prenatal genetic diagnostic (NIPD) tests are being developed using cell-free fetal DNA in the maternal circulation. NIPD avoid or reduce need for invasive procedures conditions like Down syndrome. Discussion of ethical and social implications these techniques is increasing. We report findings from a study public attitudes relevant to introduction NIPD. A key aim was examine range within diverse sample. <i>Methods:</i>...
Public bioethics bodies are used internationally as institutions with the declared aims of facilitating societal debate and providing policy advice in certain areas scientific inquiry raising questions values legitimate science. In United States, bioethical experts these use language consensus building to justify define outcome enterprise. However, implications public at science-policy boundaries underexamined. Political interest such continues while their influence on consensus, debate,...
Mucosal involvement in linear IgA disease was assessed clinically and immunologically using direct indirect immunofluorescence (IF) techniques. There clinical evidence of oral mucosal all 10 patients examined conjunctival six. Direct IF findings correlated well with disease, demonstrating deposits the basement membrane zone mucosa, However, this not true conjunctiva where no could be demonstrated. Conjunctiva did provide a good substrate for patients' sera, showed that five ro had...
Abstract Individuals now have access to an increasing number of internet resources offering personal genomics services. As the direct‐to‐consumer genetic testing (DTC GT) industry expands, critics called for pre‐ and post‐test counseling be included with product. Several companies offer counseling. There has been no examination date this service provision, whether it meets critics’ concerns implications may profession. Considering relevance genetics in healthcare, complexity information...
People can now send a sample of their saliva to an internet-based company in order discover genetic information about themselves. Entering this 'direct-to-consumer' testing (DTC GT) marketplace result enticement engage various forms 'participatory' practices, such as taking part research. In article, we analyse the research activities one largest and best-known DTC GT companies, 23andMe. 23andMe is based on what they term 'participant-led' methodologies, which utilize combination consumers'...
Pulmonary surfactant protein C (SP-C) is a 3.7-kDa, hydrophobic peptide secreted by alveolar type II epithelial cells. SP-C enhances surface tension lowering activity of phospholipids that critical to the maintenance volume at end expiration. The proinflammatory cytokine, tumor necrosis factor α (TNF-α), decreased mRNA within 24 h intratracheal administration mice. In vitro, TNF-α in time- and dose-dependent manner, reducing steady state levels 3-5-fold. contrast, induced intercellular...