A5079124644- Streptococcal Infections and Treatments
- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Neonatal and Maternal Infections
- Infective Endocarditis Diagnosis and Management
- Pharmaceutical and Antibiotic Environmental Impacts
- Bacterial Identification and Susceptibility Testing
- Vibrio bacteria research studies
- Pneumonia and Respiratory Infections
- Bacterial biofilms and quorum sensing
- Plant Pathogenic Bacteria Studies
- Infections and bacterial resistance
- Salmonella and Campylobacter epidemiology
- Antibiotics Pharmacokinetics and Efficacy
- Bacteriophages and microbial interactions
- Antibiotic Use and Resistance
- Microbial infections and disease research
- Enterobacteriaceae and Cronobacter Research
- Respiratory viral infections research
- Otolaryngology and Infectious Diseases
- Escherichia coli research studies
- Identification and Quantification in Food
- Burkholderia infections and melioidosis
- Bacterial Infections and Vaccines
- Urinary Tract Infections Management
Sakon Nakhon Rajabhat University
2016-2025
Kasetsart University
2016-2025
Faculty of Public Health
2021
Ministry of Public Health
2008-2019
Department of Medical Sciences
2008-2019
Streptococcus suis is a swine pathogen and zoonotic agent afflicting people in close contact with infected pigs or pork meat. Sporadic cases of human infections have been reported worldwide. In addition, S. outbreaks emerged Asia, making this bacterium primary health concern part the globe. pigs, disease results decreased performance increased mortality, which significant economic impact on production Facing new regulations preventive use antimicrobials livestock lack effective vaccines,...
Streptococcus suis is an emerging zoonotic swine pathogen which can cause severe infections in humans. In March 2021, outbreak of S. with 19 confirmed cases septicemia and meningitis leading to two deaths, occurred Nakhon Ratchasima province, Thailand. We characterized the through epidemiological investigation combined Illumina Nanopore whole genome sequencing (WGS). The source was traced back a raw pork dish prepared from single pig during Buddhist ceremony attended by 241 people. WGS...
Introduction. Streptococcus suis is a zoonotic pathogen that causes invasive infections in humans who have been close contact with infected pigs or contaminated pork-derived products. There currently no consensus on the universal virulence factors markers can differentiate pathogenic from non-pathogenic commensal S. isolates. Gap statement. A diagnostic tool for serotyping and pathotyping of required active public health surveillance One-Health approach. Aim. To improve former multiplex PCR...
A multiplex PCR was developed to detect all true serotypes of Streptococcus suis. This composed four reaction sets. The first set identified nine (serotypes 1/2, 1, 2, 3, 7, 9, 11, 14 and 16), the second eight 4, 5, 8, 12, 18, 19, 24 25), third seven 6, 10, 13, 15, 17, 23 31), last five 21, 27, 28, 29 30). assay correctly detected in human isolates, 14, 16, 24, 28 31 pig isolates from Thailand. No cross-reaction observed with other bacterial species. Our able simultaneously amplify a DNA...
To detect carbapenemases in clinical isolates of Enterobacteriaceae collected from patients a university hospital Thailand between October 2010 and August 2011. A total 4818 were screened for the presence by ertapenem imipenem disc diffusion tests. All positive screening subjected to modified Hodge test, phenylboronic acid– EDTA–carbapenem combined tests two multiplex PCRs blaIMP, blaVIM, blaSPM, blaSIM blaGIM, blaKPC, blaNDM blaOXA-48. Carbapenemase-producing typed PFGE then characterized...
Abstract To examine associations between clinical features of Streptococcus suis serotype 2 infections in humans Thailand and genotypic profiles isolates, we conducted a retrospective study during 2006–2008. Of 165 patients for whom bacterial cultures blood, cerebrospinal fluid, or both were positive S. 2, the major multilocus sequence types (STs) found ST1 (62.4%) ST104 (25.5%); latter is unique to Thailand. Clinical examined 158 patients. Infections sporadic; case-fatality rate adults was...
Streptococcus suis is a bacterial gram-positive pathogen that causes invasive infections in swine and also zoonotic disease agent. Traditional molecular typing techniques such as ribotyping, multilocus sequence typing, pulse-field gel electrophoresis, or randomly amplified polymorphic DNA have been used to investigate S. population structure, evolution, genetic relationships support epidemiological virulence investigations. However, these traditional do not fully reveal the genetically...
Vancomycin-resistant Enterococci (VREs) have increasingly become a major nosocomial pathogen worldwide, earning high-priority category from the World Health Organization (WHO) due to their antibiotic resistance. Among VREs, vancomycin-resistant Enterococcus faecium (VREfm) is particularly concerning, frequently isolated and resistant many antibiotics used in hospital-acquired infections. This study investigated VREfm isolates rural tertiary hospitals Northeastern Thailand based both...
Journal Article A biosurfactant from Burkholderia cenocepacia BSP3 and its enhancement of pesticide solubilization Get access H.T. Wattanaphon, Wattanaphon Graduate Program in Biotechnology, Faculty Science, Chulalongkorn University, Bangkok, Thailand Search for other works by this author on: Oxford Academic Google Scholar A. Kerdsin, Kerdsin Department Medical Sciences, National Institute Health, Ministry Public Nonthaburi, C. Thammacharoen, Thammacharoen Sensor Research Unit, Chemistry, P....
Most cases of Streptococcus suis infection in humans are caused by serotype 2 strains, and only a few other serotypes have been reported. Among 177 human isolates S. Thailand, 12 (6.8 %) were identified as being 14, an occurrence sporadic 14 was noted during 2006-2008, particularly northern Thailand. Clinical presentations the patients (median age 62.9 years) included meningitis (58.3 %), septic arthritis (25 sepsis (16.7 %). These clinical features similar to those previously reported for...
Background. Streptococcus suis is an emerging zoonotic pathogen, and causes sepsis meningitis in humans. Although sequence type (ST) 1 ST104 strains are capable of causing sepsis, ST1 commonly cause meningitis. In this study, we investigated the role suilysin, a member cholesterol-dependent cytolysins, differential pathogenicity between strains. Methods. The levels transcription translation sly gene messenger RNA both ST were compared by means quantitative polymerase chain reaction Western...
Background Streptococcus suis infection in humans has received increasing worldwide recognition. Methods and Findings A prospective study of S. was conducted Phayao Province northern Thailand to determine the incidence risk behaviors disease this region 2010. Thirty-one cases were confirmed. The case fatality rate 16.1%, estimated 6.2 per 100,000 general population. peak occurred May. median age patients 53 years 64.5% men. Consumption raw pork products confirmed 22 incubation period (range)...
Streptococcus suis is one of the most important bacterial pathogens in porcine industry and also a zoonotic agent. Serotype 9 becoming prevalent serotypes within S. population certain European countries. In present study, serotype strains isolated from country where infection due to this endemic (Spain), were compared those recovered Canada, rarely diseased pigs. For comparison purposes, Brazil only strain human case, Thailand, incorporated. Firstly, sequence types (STs) obtained followed by...
Streptococcus suis is a zoonotic pathogen of economic significance to the swine industry. The number infected cases increasing in humans worldwide. In this study, we determined prevalence and diversity S. carriage slaughterhouse pigs Phayao province, Thailand, where an outbreak occurred 2007. overall rate was 35.2% among pigs. rates serotypes 2 14 (the major humans) were 6.7% 2.6%, respectively. both serotypes, 70.4% isolates revealed sequence types pulsotypes identical human Thailand. It...
Mobile colistin-resistant genes ( mcr ) have become an increasing public health concern. Since the first report of mcr-1 in Thailand 2016, perspective surveillance was conducted to explore genomic characteristics clinical carbapenem-resistant Enterobacterales (CRE) isolates harboring 2016–2019. Thirteen (0.28%) out 4,516 CRE were found carry genes, including 69.2% (9/13) E. coli and 30.8% (4/13) K. pneumoniae isolates. Individual mcr-1.1 detected eight (61.5%) isolates, whereas co-occurrence...
Carbapenem-resistant Enterobacterales (CRE) are a serious public health threat because of their rapid dissemination. To determine the epidemiological and genetic characteristics CRE infections in Thailand, we performed whole-genome sequencing 577 carbapenem-resistant Klebsiella pneumoniae isolates 170 Escherichia coli from hospitals across nation. The four most prevalent carbapenemase genes harboured by these bacteria were bla NDM-1 , NDM-5 OXA-181 OXA-232 . gene was identified diverse...
Streptococcus suis is a major bacterial pathogen in pigs and an emerging zoonotic pathogen. Different S. serotypes exhibit diverse characteristics population structure pathogenicity. Surveillance data highlight the significance of serotype 4 (SS4) swine streptococcusis, pathotype causing human infections. However, except for few epidemiologic studies, information on SS4 remains limited. In this study, we investigated structure, pathogenicity, antimicrobial based 126 isolates, including one...
AbstractStreptococcus suis is an important zoonotic pathogen in swine and humans that causes sepsis meningitis. Our previous study Thailand showed the prevalence of S. infection humans, especially northern areas Thailand, transmission occurred mainly through consumption traditional raw pork products. Considering high incidence proportion mortality rate disease as public health problem, we implemented a food safety campaign Phayao Province 2011. We evaluated effects by comparing...
Streptococcus suis is a zoonotic pathogen that causes invasive infections in humans and pigs. It has been reported S. infection mostly caused by serotype 2. However, human cases other serotypes have rarely reported. This the first report of case with 31 Thailand. A 55-year-old male alcohol misuser liver cirrhosis was admitted sepsis to hospital Central Region He had consumed homemade, raw pork product prior onset illness. alive after treatment ceftriaxone no complication occurred. An isolate...