Filippo Del Grande

ORCID: 0000-0003-1106-5830
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About
Contact & Profiles
Research Areas
  • Medical Imaging Techniques and Applications
  • Advanced MRI Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Bone and Joint Diseases
  • Nutrition and Health in Aging
  • Shoulder Injury and Treatment
  • Tendon Structure and Treatment
  • MRI in cancer diagnosis
  • Orthopedic Surgery and Rehabilitation
  • Spine and Intervertebral Disc Pathology
  • Sarcoma Diagnosis and Treatment
  • Shoulder and Clavicle Injuries
  • Peripheral Nerve Disorders
  • Radiation Dose and Imaging
  • Advanced X-ray and CT Imaging
  • Body Composition Measurement Techniques
  • Lower Extremity Biomechanics and Pathologies
  • Knee injuries and reconstruction techniques
  • Bone Tumor Diagnosis and Treatments
  • Musculoskeletal synovial abnormalities and treatments
  • Spinal Fractures and Fixation Techniques
  • Lung Cancer Diagnosis and Treatment
  • Orthopedic Infections and Treatments
  • Sports injuries and prevention
  • Rheumatoid Arthritis Research and Therapies

Università della Svizzera italiana
2019-2025

Ente Ospedaliero Cantonale
2016-2025

Istituto Imaging della Svizzera Italiana
2020-2025

Institute of Oncology Research
2023-2024

Memorial Sloan Kettering Cancer Center
2024

Radboud University Medical Center
2024

Radboud University Nijmegen
2024

Schulthess-Klinik
2024

Johns Hopkins University
2012-2022

Ospedale regionale di Lugano
2011-2021

Background The performance of publicly available large language models (LLMs) remains unclear for complex clinical tasks. Purpose To evaluate the agreement between human readers and LLMs Breast Imaging Reporting Data System (BI-RADS) categories assigned based on breast imaging reports written in three languages to assess impact discordant category assignments management. Materials Methods This retrospective study included women who underwent MRI, mammography, and/or US cancer screening or...

10.1148/radiol.232133 article EN Radiology 2024-04-01

Purpose To determine the added value of functional magnetic resonance (MR) sequences (dynamic contrast material–enhanced [DCE] and quantitative diffusion-weighted [DW] imaging with apparent diffusion coefficient [ADC] mapping) for detection recurrent soft-tissue sarcomas following surgical resection. Materials Methods This retrospective study was approved by institutional review board. The requirement to obtain informed consent waived. Thirty-seven patients referred postoperative...

10.1148/radiol.13130844 article EN Radiology 2014-02-04

OBJECTIVE Navigation-enabling technology such as 3D-platform (O-arm) or intraoperative mobile CT (iCT-Airo) systems for use in spinal surgery has considerably improved accuracy over that of traditional fluoroscopy-guided techniques during pedicular screw positioning. In this study, the authors compared 2 imaging with navigation, available their neurosurgical unit, terms they provided transpedicular fixation thoracic and lumbar spine. METHODS The performed a retrospective analysis clinical...

10.3171/2018.1.spine17927 article EN Journal of Neurosurgery Spine 2018-07-06

Background Rapid knee MRI using combined simultaneous multislice (SMS) technique and parallel imaging (PI) acceleration can add value through reduced acquisition time but requires validation of clinical efficacy. Purpose To evaluate the performance fourfold SMS-PI-accelerated, 5-minute, five-sequence, multicontrast protocols compared with standard twofold PI-accelerated, 10-minute protocols. Materials Methods Adults painful conditions were prospectively enrolled from April 2018 to October...

10.1148/radiol.2021203655 article EN Radiology 2021-04-06

Abstract Background Body composition scores allow for quantifying the volume and physical properties of specific tissues. However, their manual calculation is time-consuming prone to human error. This study aims develop validate CompositIA , an automated, open-source pipeline body from thoraco-abdominal computed tomography (CT) scans. Methods A retrospective dataset 205 contrast-enhanced CT examinations was used training, while 54 scans a publicly available were independent testing. Two...

10.1186/s41747-025-00552-7 article EN cc-by European Radiology Experimental 2025-01-29

The impact of new asymptomatic spinal cord lesions (a-SL) in multiple sclerosis (MS) course is poorly characterized.The objective this research paper to assess the prognostic value a-SL predicting MS course.Relapsing-remitting patients who received serial MRI (brain and spinal) at baseline (t1) within 12 36 months (t2) during clinical stability, had a follow-up (t2-t3) ⩾24 were included. Relapses disability progression evaluated between t2 t3.Of 413 consecutive screened patients, 103 (65...

10.1177/1352458515599246 article EN Multiple Sclerosis Journal 2015-10-12

The purpose of this article is to evaluate the significance subspecialty second-opinion consultations for CT and MRI examinations in musculoskeletal (MSK) radiology.All 3165 MSK referred one academic institution consultation during a 24-month period were reviewed by three MSK-trained radiologists. Outside inside reports compared two independent radiology fellows using previously published 5-point scale. Clinically important differences (categories 4 5) defined as those likely change patient...

10.2214/ajr.15.14540 article EN American Journal of Roentgenology 2016-04-09

Background To assess the interobserver reliability of three selective region‐of‐interest (ROI) measurement protocols for apparent diffusion coefficient (ADC) quantifications in soft tissue masses (STMs) compared with whole tumor volume (WTV) ADC measurements. Methods Institutional review board approval was obtained and informed consent waived. Three observers independently measured minimum mean ADCs 73 benign malignant musculoskeletal STMs using methods (single‐slice [SS], predefined slices...

10.1002/jmri.24994 article EN Journal of Magnetic Resonance Imaging 2015-07-14

Objectives The aim of this study was to test the hypothesis that magnetic resonance imaging (MRI) knee with 10-minute 3-dimensional (3D) controlled aliasing in parallel results higher acceleration (CAIPIRINHA) sampling perfection application optimized contrast using different flip angle evolutions (SPACE) turbo spin echo (TSE) protocols can replace 20-minute 2-dimensional (2D) TSE standard-of-reference for diagnosis internal derangement. Materials and Methods After review board approval...

10.1097/rli.0000000000000493 article EN Investigative Radiology 2018-08-07

Study Design. A prospective multicenter cohort study. Objective. The aim of this study was to identify an association between pain and magnetic resonance imaging (MRI) parameters in patients with lumbar spinal stenosis (LSS). Summary Background Data. At present, the relationship abnormal MRI findings LSS is still unclear. Methods. First, we conducted a systematic literature search. We identified relationships relevant LSS. Second, addressed question thorough descriptive graphical analysis...

10.1097/brs.0000000000001544 article EN Spine 2016-03-03

To evaluate whether a model based on radiomic and clinical features may be associated with lymph node (LN) status overall survival (OS) in lung cancer (LC) patients; to CT reconstruction algorithms influence the performance.patients operated for LC pathological stage up T3N1 were retrospectively selected divided into training validation sets. For prediction of positive LNs OS, Least Absolute Shrinkage Selection Operator (LASSO) logistic regression was used; univariable multivariable analysis...

10.3390/cancers12061432 article EN Cancers 2020-05-31
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