A5044115824- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Lightning and Electromagnetic Phenomena
- Radiation Therapy and Dosimetry
- Fire effects on ecosystems
- Nuclear physics research studies
- Hematopoietic Stem Cell Transplantation
- Advanced X-ray and CT Imaging
- Nuclear Physics and Applications
- Biomedical Ethics and Regulation
- Erythrocyte Function and Pathophysiology
- Lung Cancer Diagnosis and Treatment
- Platelet Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Advanced Chemical Physics Studies
- X-ray Spectroscopy and Fluorescence Analysis
- Radiation Dose and Imaging
- CRISPR and Genetic Engineering
- Atomic and Molecular Physics
- Effects of Radiation Exposure
- Management of metastatic bone disease
- Catalytic Processes in Materials Science
- Meteorological Phenomena and Simulations
- Acute Lymphoblastic Leukemia research
- Economic and Financial Impacts of Cancer
Vaisala (United States)
2010-2025
Health Research Board
2024
Ollscoil na Gaillimhe – University of Galway
2024
Trials Methodology Research Network
2024
Virginia Commonwealth University
2007-2022
Fermi National Accelerator Laboratory
2018-2022
Business Roundtable
2018-2020
Society for Translational Oncology
2014-2016
AlphaMed (United States)
1988-2015
University of Iowa
1978-2012
This document is the report of a task group AAPM and has been prepared primarily to advise medical physicists involved in external-beam radiation therapy patients with thoracic, abdominal, pelvic tumors affected by respiratory motion. describes magnitude motion, discusses radiotherapy specific problems caused explains techniques that explicitly manage motion during gives recommendations application these for patient care, including quality assurance (QA) guidelines devices their use...
The U.S. National Lightning Detection Network TM (NLDN) has provided lightning data covering the continental United States since 1989. Using information gathered from more than 100 sensors, NLDN provides both real‐time and historical to electric utility industry, Weather Service, other government commercial users. It is also primary source of for use in research climatological studies States. In this paper we discuss design, implementation, time‐of‐arrival/magnetic direction finder (TOA/MDF)...
Lightning in all corners of the world is monitored by one or more land- space-based lightning locating systems (LLSs). The applications that have driven these developments are numerous and varied. This paper describes history leading to modern LLSs sense radiation fields at multiple remote sensors, focusing on interactions between enabling technology, scientific discovery, technical development, uses data. An overview widely used detection location methods provided, including a general...
The Cyberknife is a unique instrument for performing frameless stereotactic radiosurgery. Rather than using rigid immobilization, the relies on an image-to-image correlation algorithm target localization. Furthermore, system utilizes novel, light-weight, high-energy radiation source. authors describe technical specifications of and summarize initial clinical experience.
Radiographic image guidance has emerged as the new paradigm for patient positioning, target localization, and external beam alignment in radiotherapy. Although widely varied modality method, all radiographic techniques have one thing common--they can give a significant radiation dose to patient. As with medical uses of ionizing radiation, general view is that this exposure should be carefully managed. The philosophy management adopted by diagnostic imaging community summarized acronym ALARA,...
PURPOSE: To describe the design and performance of a novel frameless system for radiosurgery. This technology, called image-guided radiosurgery (IGR), eliminates need stereotactic frame fixation by relating identified lesion to radiographic landmarks. CONCEPT: IGR uses lightweight x-band linear accelerator, computer-controlled robotic arm (Fanuc manipulator [Fanuc Robotics North America, Inc., Rochester Hills, MI]), paired orthogonal x-ray imagers, computer workstation that performs rapid...
Abstract Ground‐based and satellite‐based lightning locating systems are the most common ways to detect geolocate lightning. Depending upon frequency range of operation, LLSs may report a variety processes characteristics associated with flashes including channel formation, leader pulses, cloud‐to‐ground return strokes, M‐components, ICC cloud location, duration, peak current, radiated power energy, full spatial extent channels. Lightning data from different types often provide complementary...
MAGIS-100 is a next-generation quantum sensor under construction at Fermilab that aims to explore fundamental physics with atom interferometry over 100-meter baseline. This novel detector will search for ultralight dark matter, test mechanics in new regimes, and serve as technology pathfinder future gravitational wave detectors previously unexplored frequency band. It combines techniques demonstrated state-of-the-art 10-meter-scale interferometers the latest technological advances of world's...
AbstractTumors in the chest and abdomen move during respiration. The ability of conventional radiation therapy systems to compensate for respiratory motion by moving source is inherently limited. Since safety margins currently used increase dose a very large amount, an accurate tracking method following tumor utmost clinical relevance. We investigate methods using robotic radiosurgery. Thus, therapeutic beam moved arm, follows target tumor. To determine precise position target, we combine...
Abstract OBJECTIVE This article demonstrates the technical feasibility of noninvasive treatment unresectable spinal vascular malformations and primary metastatic tumors by use image-guided frameless stereotactic radiosurgery. METHODS Stereotactic radiosurgery delivers a high dose radiation to tumor volume or malformation in limited number fractions minimizes adjacent normal structures. Frameless was developed coupling an orthogonal pair x-ray cameras dynamically manipulated robot-mounted...
Tumors in the chest and abdomen move during respiration. The ability of conventional radiation therapy systems to compensate for respiratory motion by moving source is inherently limited. Since safety margins currently used increase dose a very large amount, an accurate tracking method following tumor utmost clinical relevance. We investigate methods using robotic radiosurgery. Thus, therapeutic beam moved arm, follows target tumor. To determine precise position target, we combine infrared...
Binding of 5,10,15,20-tetrakis(N-methylpyridiniutn-4-yl)porphyrin (H 2 TMPyP 4+ ) and its zinc complex (ZnTMPyP to DNA is demonstrated by their coelectrophoresis absorption fluorescence spectroscopic methods. Topoisoinerisation pBR322 shows that H unwinds as efficiently ethidium bromide showing it intercalates at many sites. ZnTMPyP may cause limited unwinding. Marked changes in the spectra porphyrins are found presence DNA. The intensity either or enhanced poly (d(A–T)), whereas (d(G–C))...
ABSTRACT In this paper, the existence of two A-type cyclins in mouse is demonstrated. adult mouse, expression cyclin A1, which has greatest sequence identity with Xenopus restricted to germ cells. contrast A2, human A and expressed all tissues analysed. order explore function A1 cells, its during meiotic cell cycle associated kinase subunits have been characterised testis. The levels mRNA rise dramatically late pachytene spermatocytes become undetectable soon after completion divisions; thus...
Horizontal and line‐normal, vertical cross‐sections composite images of Dallas‐Fort Worth Lightning Detection Ranging (LDAR II) VHF radiation sources radar reflectivity over a 30‐min period provide unique perspective on lightning pathways within leading‐line, trailing‐stratiform (LLTS) mesoscale convective system (MCS) 16 June 2002. The overwhelming majority occurred the leading line in bimodal pattern vertical. Assuming that source density maxima were most likely associated with positive...
Abstract Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for cancer. Due to mechanism of action ICIs, inflammatory reactions against normal tissue were an anticipated side effect these agents; immune-related adverse events been documented and are typically low grade manageable. Myocarditis has emerged as uncommon but potentially life-threatening reaction in patients treated with ICIs. Assessment characterization ICI-associated myocarditis is challenging because...
There are many models for sharing clinical-trial data. These investigators provide their viewpoint on why an open-data model has value over others.
A frameless radiosurgical treatment system has been developed by coupling an orthogonal pair of real-time x-ray cameras to a robotically manipulated linear accelerator guide the therapy beam sites within patient's cranium. The two observe position and orientation head in coordinate frame. An image registration algorithm compares radiographs corresponding digitally synthesized derived from CT study patient. determines all six degrees translational rotational difference between frame its room...