A5100379655- Advanced biosensing and bioanalysis techniques
- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Carbon and Quantum Dots Applications
- Nanocluster Synthesis and Applications
- RNA Interference and Gene Delivery
- Biosensors and Analytical Detection
- DNA and Nucleic Acid Chemistry
- Molecular Sensors and Ion Detection
- Photoacoustic and Ultrasonic Imaging
- Sulfur Compounds in Biology
- Selenium in Biological Systems
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Luminescence and Fluorescent Materials
- Food composition and properties
- Gold and Silver Nanoparticles Synthesis and Applications
- Epigenetics and DNA Methylation
- Lanthanide and Transition Metal Complexes
- Electrochemical sensors and biosensors
- Microfluidic and Capillary Electrophoresis Applications
- Quantum Dots Synthesis And Properties
- MicroRNA in disease regulation
- RNA and protein synthesis mechanisms
- Trace Elements in Health
Guangxi Normal University
2016-2025
Guangdong Pharmaceutical University
2024-2025
Shaanxi Coal Chemical Industry Technology Research Institute
2025
Changzhi Medical College
2018-2025
Hebei General Hospital
2024
State Forestry and Grassland Administration
2024
Yangzhou University
2023-2024
Shougang Institute of Technology
2024
East China University of Science and Technology
2019-2024
China Iron and Steel Research Institute Group
2024
Chemical doping with heteroatoms can effectively modulate physicochemical and photochemical properties of carbon dots (CDs). However, the development multi codoped nanodots is still in its early stage. In this work, a facile hydrothermal synthesis strategy was applied to synthesize (nitrogen phosphorus) (N,P-CDs) using glucose as source, ammonia, phosphoric acid dopant, respectively. Compared CDs, doped CDs resulted dramatic improvement electronic characteristics surface chemical activities....
Fluorescent carbon dots derived from peanut shells were prepared <italic>via</italic> a pyrolysis approach and used for living cell imaging.
The ratiometric fluorescence assay, which can eliminate the external effects, has attracted great attention. In this work, a carbon dot (CD)-based nanohybrid dual-emission system was simply prepared by unique approach of solvothermal treating corn bract and used as fluorescent sensor for Hg2+ detection. Under single excitation, obtained had two emission bands around 470 678 nm, may originate from intrinsic structure CDs chlorophyll-derived porphyrins, respectively. presence Hg2+, at nm could...
The tumor microenvironment–activated Fe-Cu@PANI nanoprobe is used for photoacoustic imaging and photothermal therapy.
Fluorescent carbon dots (CDs) originated from natural biomass have been of great interest in recent years because their superior optical and chemical properties. However, previously reported CDs used only one as precursor, the fluorescence quantum yield (QY) long-wavelength emissions are usually weak, which restrict further applications biology-relevant fields. Here a green method was demonstrated for preparation S N codoped fluorescent (S,N/CDs) by adopting two biomasses (water chestnut...
The ability to detect spatial and temporal microRNA (miRNA) distribution at the single-cell level is essential for understanding biological roles of miRNAs miRNA-associated gene regulatory networks. We report first time development a target-primed RCA (TPRCA) strategy highly sensitive selective in situ visualization miRNA expression patterns level. This uses circular DNA as probe hybridization (ISH) with target molecules, free 3′ terminus then initiates an reaction generate long tandem...
Tumor microenvironment (TME)-activated cancer imaging and therapy is a key to achieving accurate diagnosis treatment of reducing the side effects. Herein, smart near-infrared carbon dot-metal organic framework MIL-100 (Fe) assemblies are constructed achieve TME-activated chemodynamic-photothermal combined therapy. First, emission dot (RCDs) developed using glutathione (GSH) as precursor. Then, RCDs@MIL-100 self-assemblies obtained RCDs, FeCl3 , trimesic acid solutions raw materials. After...
An artificial LHS with red emission based on pillar[5]arene was fabricated using 1% Nile as the energy acceptor. The prepared powder successfully used for high-contrast fluorescence imaging of latent fingerprints.
DNA motors have attracted extensive interest in biosensing and bioimaging. However, the amplification capacity of existing motor systems is limited since products from walking process are unable to feedback into original systems. As a result, sensitivities such contexts In this study, we report novel self-feedback DNAzyme for sensitive imaging tumor-related mRNA live cells vivo with cascade signal capacity. Gold nanoparticles (AuNPs) modified hairpin-locked walker track strands formed by...
Abstract J‐aggregation brings intriguing optical and electronic properties to molecular dyes significantly expands their applicability across diverse domains, yet the challenge for rationally designing J‐aggregating persists. Herein, we developed a large number of from scratch by progressively refining structure common heptamethine cyanine. J‐aggregates with sharp spectral bands (full‐width at half‐maximum≤38 nm) are attained introducing branched featuring benzyl trifluoroacetyl group...
DNA walker, a type of dynamic device that is capable moving progressively along prescribed walking tracks, has emerged as an ideal and powerful tool for biosensing bioimaging. However, most the reported three-dimensional (3D) walker were merely designed detection single target, they not achieving universal applicability. Herein, we first time development proximity-induced 3D bipedal imaging low abundance biomolecules. As proof concept, miRNA-34a, biomarker breast cancer, chosen model system...
A highly selective electrochemical biosensor for the ultrasensitive detection of Hg2+ in aqueous solution has been developed based on strong and specific binding by two DNAthymine bases (T–Hg2+–T) use AuNP-functionalized reporter DNA to achieve signal amplification.
In this work, we report a reducing agent-free strategy for the synthesis of Fe3O4 nanoparticle/nitrogen-doped graphene quantum dot (Fe3O4/N-GQD) hybrids, and constructed sensing platform based on Fe3O4/N-GQDs visual discrimination phenylenediamine isomers. were facilely prepared by hydrothermal treatment Fe3+/N-GQD solutions under alkaline conditions without other reagents. The exhibited outstanding peroxidase-like activity stable wide range pH values temperatures. isomers...
In situ spatiotemporal microRNA (miRNA) imaging in mammal cells plays an essential role illustrating its structures and biological functions. Herein, we proposed a near-infrared (NIR) light-activated nanoprobe for high-sensitive controllable miRNA living cells. The NIR-activated employed upconversion nanoparticle that acted as NIR-to-UV transducer to trigger the following photocleavage toward dumbbell DNA probe tethered on surface of nanoparticle. structure change then induced catalytic...