A5057557910- Marine Ecology and Invasive Species
- Marine Biology and Ecology Research
- Developmental Biology and Gene Regulation
- Planarian Biology and Electrostimulation
- Cephalopods and Marine Biology
- Marine Biology and Environmental Chemistry
- Marine Invertebrate Physiology and Ecology
- Neurobiology and Insect Physiology Research
- Physiological and biochemical adaptations
- Insect and Arachnid Ecology and Behavior
- Marine and coastal plant biology
- Marine and environmental studies
- Cavitation Phenomena in Pumps
- Food Industry and Aquatic Biology
- Paleontology and Evolutionary Biology
- Wnt/β-catenin signaling in development and cancer
- Invertebrate Immune Response Mechanisms
- Fish Ecology and Management Studies
- Genetics, Aging, and Longevity in Model Organisms
- Aquatic life and conservation
- Reproductive biology and impacts on aquatic species
- Aquaculture disease management and microbiota
- Environmental Toxicology and Ecotoxicology
- Ichthyology and Marine Biology
- Animal Genetics and Reproduction
St Petersburg University
2014-2024
University of Vienna
2014-2019
Max Perutz Labs
2014-2019
The molecular mechanisms by which animals integrate external stimuli with internal energy balance to regulate major developmental and reproductive events still remain enigmatic. We investigated this aspect in the marine bristleworm, Platynereis dumerilii , a species where sexual maturation is tightly regulated both metabolic state lunar cycle. Our specific focus was on ligands receptors of gonadotropin-releasing hormone (GnRH) superfamily. Members superfamily are key triggering vertebrates...
Segmentation is one of the most striking features bilaterians, and understanding its mechanisms provides insights into evolution body plans. In annelids, segmentation occurs at different developmental stages through a variety processes, yet molecular pathways remain underexplored. Aiming to compare patterns in ontogeny phylogeny, we analysed expression Avi-en (homologous engrailed) Avi-wnt1 nereidid polychaete Alitta virens. Using situ hybridization, immunofluorescence, cell proliferation...
The advent of high-throughput sequencing technology facilitates the exploration a variety reference species outside few established molecular genetic model systems. Bioinformatic and gene expression analyses provide new ways for comparative between species, instance, in field evolution development. Despite these advances, critical bottleneck remains establishment functional tools, such as ability to experimentally express genes specific cells an organism. We recently first transgenic strain...
foxA orthologs are involved in various processes from embryo patterning to regulation of metabolism. Since conserved role the development gut errant annelids has never been thoroughly studied, we used a candidate gene approach unravel molecular profile alimentary canal two closely related nereid worms with trochophore-type lecithotrophic larva.The character expression polychaetes was similar but not identical. The genes were successively activated first blastoporal cells, then stomodeum,...
In recent years, interest in the possible molecular regulators of cell proliferation and differentiation a wide range regeneration models has grown significantly, but kinetics this process remain largely mystery. Here we try to elucidate cellular aspects by EdU incorporation intact posteriorly amputated annelid Alitta virens using quantitative analysis. We found that main mechanism blastema formation A. is local dedifferentiation; mitotically active cells segments do not significantly...
Epimorphic regeneration of lost body segments is a widespread phenomenon across annelids. However, the molecular inducers cell sources for this reparative morphogenesis have not been identified. In study, we focused on role fibroblast growth factor (FGF) signaling in posterior Alitta virens. For first time, showed an early activation FGF ligands and receptor expression annelid regenerating after amputation. The patterns indicate that entire regenerative bud competent to FGFs, whose activity...
Fibroblast growth factor signaling plays a crucial role in various developmental processes and is key driver of regeneration. In annelids this pathway active from the earliest stages reparative morphogenesis, yet its specific function remains unclear. Here we have functionally examined FGF following amputation posterior segments marine annelid Alitta virens . We utilized pharmacological agent SU5402 to inhibit receptor kinase at different time points. With whole-mount situ hybridization...
The study of interannual changes in the structure soft soil macrobenthic communities was carried out on basis material collected three littoral sites waters Keret archipelago White Sea 1983– 2013. analyzed differed biotopic heterogeneity (characteristics soil, degree closure water areas, salinity regime). This is a sandy beach seaward zone, and two silt-sandy beaches semi-enclosed practically closed area. latter located near mouth River, also under influence lake runoff, respectively,...