Jonny J. Blaker

ORCID: 0000-0003-1112-8619
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About
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Research Areas
  • Bone Tissue Engineering Materials
  • Electrospun Nanofibers in Biomedical Applications
  • biodegradable polymer synthesis and properties
  • Silk-based biomaterials and applications
  • Advanced Cellulose Research Studies
  • Additive Manufacturing and 3D Printing Technologies
  • Advanced Sensor and Energy Harvesting Materials
  • 3D Printing in Biomedical Research
  • Graphene and Nanomaterials Applications
  • Pickering emulsions and particle stabilization
  • Surface Modification and Superhydrophobicity
  • Dental materials and restorations
  • Natural Fiber Reinforced Composites
  • Surgical Sutures and Adhesives
  • Advanced Materials and Mechanics
  • Tissue Engineering and Regenerative Medicine
  • Wound Healing and Treatments
  • Nanocomposite Films for Food Packaging
  • Orthopaedic implants and arthroplasty
  • Neurobiology and Insect Physiology Research
  • Proteins in Food Systems
  • Nanofabrication and Lithography Techniques
  • Dental Implant Techniques and Outcomes
  • Fiber-reinforced polymer composites
  • Facial Trauma and Fracture Management

University of Oslo
2020-2025

Henry Royce Institute
2020-2025

University of Manchester
2016-2025

Institute of Clinical Research
2025

Imperial College London
2003-2012

King's College London
2007-2008

Scaffolds are physical substrates for cell attachment, proliferation, and differentiation, ultimately leading to the regeneration of tissues. They must be designed according specific biomechanical requirements, i.e., certain standards in terms mechanical properties, surface characteristics, porosity, degradability, biocompatibility. The optimal design a scaffold tissue strongly depends on both materials manufacturing processes, as well treatment. Polymeric scaffolds reinforced with...

10.3390/ma9120992 article EN Materials 2016-12-07

Abstract Highly porous poly( DL ‐lactic acid) (PDLLA) foams and Bioglass®‐filled PDLLA composite were characterized evaluated in vitro as bone tissue engineering scaffolds. The hypothesis was that the combination of with Bioglass® a structure would result bioresorbable bioactive composite, capable supporting osteoblast adhesion, spreading viability. Composite unfilled incubated simulated body fluid (SBF) at 37°C to study degradation polymer detect hydroxyapatite (HA) formation, which is...

10.1002/jbm.a.20055 article EN Journal of Biomedical Materials Research Part A 2003-11-06

The effect of surface functionalisation bacterial cellulose nanofibrils (BC) and their use as reinforcement for polylactide (PLLA) nanocomposites was investigated. BC functionalised with various organic acids via an esterification reaction. This rendered the otherwise hydrophilic hydrophobic resulted in better compatibility (interfacial adhesion) between PLLA BC. A direct wetting method, allowing determination contact angle polymer droplets on a single nanofibre, developed to quantify...

10.1016/j.compscitech.2009.08.016 article EN cc-by-nc-nd Composites Science and Technology 2009-09-03

The design of bioactive scaffolds with improved mechanical and biological properties is an important topic research. This paper investigates the use polymer-ceramic composite for bone tissue engineering. Different ceramic materials (hydroxyapatite (HA) β-tri-calcium phosphate (TCP)) were mixed poly-ε-caprolactone (PCL). Scaffolds different material compositions produced using extrusion-based additive manufacturing system. physically chemically assessed, considering mechanical, wettability,...

10.3390/ma11010129 article EN Materials 2018-01-14

Recent interest in the utilisation of greener materials has reinitiated natural fibres and/or fibrils as reinforcement for polymers.However, such bio-based composites often exhibit properties that fall short expectations due to (i) inadequate processing conditions, resulting filler agglomeration and poor dispersion within matrix, (ii) variations fibre properties, geographical seasonal variability, (iii) anisotropy themselves, (iv) high linear coefficient thermal expansion (v) incompatibility...

10.1166/jbmb.2011.1113 article EN Journal of Biobased Materials and Bioenergy 2011-03-01

Vitrimers with 1 : to 2 epoxy/acid ratio and TBD show increased stiffness gradual transition from an exchangeable non-exchangeable network.

10.1039/d0py00342e article EN Polymer Chemistry 2020-01-01

Design strategies for small diameter vascular grafts are converging toward native-inspired tissue engineered grafts. A new automated technology is presented that combines a dip-spinning methodology depositioning concentric cell-laden hydrogel layers, with an adapted solution blow spinning (SBS) device intercalated placement of aligned reinforcement nanofibres. This additive manufacture approach allows the assembly bio-inspired structural configurations cell patterns fibres at specific angles...

10.1038/s41467-019-11090-3 article EN cc-by Nature Communications 2019-07-15

Skin defects are amongst the main causes of morbidity and mortality worldwide, which account for significantly high socioeconomic costs. Today, much attention is being paid to tissue engineering biomaterials strategies skin regeneration, among them, there increasing interest in using multigradient biomaterials. Gradient-based approaches an emerging trend homogeneous delivery therapeutic agents by Several studies have acknowledged that wound repair mechanisms could be enhanced through...

10.1016/j.mtadv.2019.100051 article EN cc-by Materials Today Advances 2020-01-08
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