A5073190780- Sphingolipid Metabolism and Signaling
- MicroRNA in disease regulation
- Adipokines, Inflammation, and Metabolic Diseases
- Cancer-related molecular mechanisms research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Autophagy in Disease and Therapy
- Adipose Tissue and Metabolism
- Apelin-related biomedical research
- Circular RNAs in diseases
Asan Medical Center
2022-2024
University of Ulsan
2022-2024
Ulsan College
2022-2024
C1q/tumor necrosis factor–related protein 9 (CTRP9) is an adipokine and has high potential as a therapeutic target. However, the role of CTRP9 in cardiovascular disease pathogenesis remains unclear. We found to induce HDAC7 p38 MAPK phosphorylation via tight regulation AMPK vascular endothelial cells, leading angiogenesis through increased MEF2 activity. The expression atheroprotective was decreased plaque tissue atherosclerotic patients ventricle post-infarction mice. treatment inhibited...
Cardiovascular disease (CVD) remains a global health challenge, primarily due to atherosclerosis, which leads conditions such as coronary artery disease, cerebrovascular and peripheral arterial disease. Mitochondrial dysfunction initiates endothelial dysfunction, key contributor CVD pathogenesis, well triggers the accumulation of reactive oxygen species (ROS), energy stress, cell death in cells, are crucial for atherosclerosis development. This review explores role PTEN-induced protein...