A5040752371- Organometallic Complex Synthesis and Catalysis
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Asymmetric Hydrogenation and Catalysis
- Metal complexes synthesis and properties
- Crystallography and molecular interactions
- Organometallic Compounds Synthesis and Characterization
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Chemical Synthesis and Analysis
- Crystal structures of chemical compounds
- Catalytic Cross-Coupling Reactions
- Magnetism in coordination complexes
- Coordination Chemistry and Organometallics
- Bone Tissue Engineering Materials
- Synthesis and Reactions of Organic Compounds
- Plant and fungal interactions
- Carbon dioxide utilization in catalysis
- Synthesis and Catalytic Reactions
- Catalytic C–H Functionalization Methods
- Synthesis and Biological Evaluation
- Molecular Biology Techniques and Applications
- Carbohydrate Chemistry and Synthesis
- Cyclopropane Reaction Mechanisms
- Metal-Organic Frameworks: Synthesis and Applications
University of Bologna
2010-2020
Ospedale San Giacomo Apostolo
2020
University of Perugia
1998-2007
University of Florence
2002
Max Planck Society
2000
University of Edinburgh
1993
Collegio Carlo Alberto
1993
University of Cambridge
1990-1993
University of Łódź
1992
Scuola Normale Superiore
1991
One of the main obstacles toward discovery effective anti-Alzheimer drugs is multifactorial nature its etiopathology. Therefore, use multitarget-directed ligands has emerged as particularly suitable. Such ligands, able to modulate different neurodegenerative pathways, for example, amyloid and tau cascades, well cognitive neurogenic functions, are fostered come. In this respect, we report herein on first class BACE-1/GSK-3β dual inhibitors based a 3,4-dihydro-1,3,5-triazin-2(1H)-one skeleton,...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHydrogen Bonding in Organometallic Crystals. 1. From Carboxylic Acids and Alcohols to Carbonyl ComplexesDario Braga, Fabrizia Grepioni, Piera Sabatino, Gautam R. DesirajuCite this: Organometallics 1994, 13, 9, 3532–3543Publication Date (Print):September 1, 1994Publication History Published online1 May 2002Published inissue 1 September 1994https://pubs.acs.org/doi/10.1021/om00021a029https://doi.org/10.1021/om00021a029research-articleACS...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTransition-metal-promoted cyclization reactions of isocyanide ligands. Synthesis cyclic diaminocarbenes from complexes palladium(II) and platinum(II) x-ray structure cis-Br2Pt[CN(C6H4-p-Me)CH2CH2N(H)](PPh3)Rino A. Michelin, Livio Zanotto, Dario Braga, Piera Sabatino, Robert J. AngeliciCite this: Inorg. Chem. 1988, 27, 1, 93–99Publication Date (Print):January 1988Publication History Published online1 May 2002Published inissue 1 January...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLewis acid-promoted 1,4-addition to chiral imide derivatives in the synthesis of .beta.-amino acidsRosa Amoroso, Giuliana Cardillo, Piera Sabatino, Claudia Tomasini, and Alessandra TrereCite this: J. Org. Chem. 1993, 58, 21, 5615–5619Publication Date (Print):October 1, 1993Publication History Published online1 May 2002Published inissue 1 October 1993https://pubs.acs.org/doi/10.1021/jo00073a017https://doi.org/10.1021/jo00073a017research-articleACS...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTransition-metal-promoted cyclization reactions of isocyanide ligands. Synthesis cyclic aminooxycarbene complexes platinum(II) and x-ray structure trans-[(PPh3)2Pt[CN(C6H4Me-p)CH2CH2O]Br]BF4Rino A. Michelin, Livio Zanotto, Dario Braga, Piera Sabatino, Robert J. AngeliciCite this: Inorg. Chem. 1988, 27, 1, 85–92Publication Date (Print):January 1988Publication History Published online1 May 2002Published inissue 1 January...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOxidative addition of phenols to bis(tricyclohexylphosphine)palladium. Synthesis and structural characterization trans-[Pd(PCy3)2(H)(OC6H5)].C6H5OH (1) trans-[Pd(PCy3)2(H)(OC6F5)].C6F5OH (2)C. Di Bugno, M. Pasquali, P. Leoni, Sabatino, D. BragaCite this: Inorg. Chem. 1989, 28, 7, 1390–1394Publication Date (Print):April 1, 1989Publication History Published online1 May 2002Published inissue 1 April...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCoordinated water/anion hydrogen bonds and Pd-H bond acidity in cationic palladium(II) aquo hydrides the x-ray crystal molecular structures of trans-[(Cy3P)2Pd(H)(H2O)]BF4 (Cy = cyclohexyl)Piero Leoni, Milena Sommovigo, Marco Pasquali, Stefano Midollini, Dario Braga, Piera SabatinoCite this: Organometallics 1991, 10, 4, 1038–1044Publication Date (Print):April 1, 1991Publication History Published online1 May 2002Published inissue 1 April...
In this study cytotoxicity of organotin(IV) compounds with 1,2,4-triazolo[1,5-a]pyrimidines, Me3Sn(5tpO) (1), n-Bu3Sn(5tpO) (2), Me3Sn(mtpO) (3), n-Bu3Sn(mtpO) (4), n-Bu3Sn(HtpO2) (5), Ph3Sn(HtpO2) (6) where 5HtpO = 4,5-dihydro-5-oxo-[1,2,4]triazolo-[1,5-a]pyrimidine, HmtpO 4,7-dihydro-5-methyl-7-oxo-[1,2,4]triazolo-[1,5-a]pyrimidine, and H2tpO2 4,5,6,7-tetrahydro-5,7- dioxo-[1,2,4]triazolo-[1,5-a]-pyrimidine, was assessed on three different human tumor cell lines: HCT-116 (colorectal...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFunctionalized isocyanides as ligands. 4. Base-promoted cyclization reactions of free and platinum(II)-coordinated o-(phosphoniomethyl)phenyl isocyanide tetrafluoroborates, o-(BF4-R3PCH2)C6H4NC. Synthesis spectroscopic characterization 1- 2-platinum(II)-substituted indole derivatives x-ray structure [cyclic] trans-.+-.[(PPh3)2Pt[CN(H)-o-C6H4C(PMe3)]Cl.+-.]Bf4.+-..C2H4Cl2Rino A. Michelin, Giacomo. Facchin, Dario. Braga, Piera. SabatinoCite this:...
It has previously been shown that replacement of the residue His L168 with Phe (HL168F) in <i>Rhodopseudomonas viridis</i> reaction center (RC) leads to an unprecedented drastic acceleration initial electron transfer rate. Here we describe determination x-ray crystal structure at 2.00-Å resolution HL168F RC. The density maps confirm a hydrogen bond from protein special pair is removed by this mutation. Compared wild-type RC, acceptor bond, ring I acetyl group "special pair"...
Reaction of the square-pyramidal cluster [Ru5C(CO)15]1 with cyclohexa-1,3-diene and Me3NO in CH2Cl2 at ambient temperature affords novel species [Ru5C(CO)13(µ-η2:η2-C6H8)]2 which has been fully characterized by X-ray diffraction studies [monoclinic, space group P21/n, a= 16.193(3), b= 9.897(2), c= 19.536(4)Å, β= 98.80(3)° Z= 4]. Further reaction compound 2 same solvent results dehydrogenation C6H8 ligand production two isomers 3a 3b benzene derivative [Ru5C(CO)12(C6H6)]. In agreement mass...
The molecular organization in crystals of [Co2(CO)8] and [Fe2(CO)9] has been investigated by means packing potential-energy calculations computer graphic analysis. It is shown that the two molecules pack nearly identical ways their crystals. However, while crystalline compact, solid presents large empty channels (van der Waals width between 2.4 4.5 Å, at room temperature) corresponding to approximate location possible residual electron density (whether due Co–Co bonding electrons or lone...
Purpose Natural resources are receiving growing interest because of their possible conversion from a cheap and easily available material into biomedical product. Cuttlefish bone Sepia Officinalis was investigated in order to obtain an hydroxyapatite porous scaffold using hydrothermal transformation. Methods Complete the previous calcium carbonate (aragonite) phase phosphate (hydroxyapatite) performed with transformation at 200 °C (∼15 atm), for four hours, aqueous solution KH 2 PO 4 set...
Abstract The possibility to prepare bioinspired collagen nanofibers by electrospinning from aqueous suspension of telopeptide‐free molecules avoiding both organic solvents and blends with any synthetic natural polymers has been investigated. results have highlighted the need for a basic atmosphere between needle ground collector in order increase environmental pH during self‐assembly along electrostatic force lines. Morphological, spectroscopic calorimetric analyses carried out on...