A5043703551- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Regulation of Appetite and Obesity
- Diet, Metabolism, and Disease
- Hormonal Regulation and Hypertension
- Stress Responses and Cortisol
- Biochemical Analysis and Sensing Techniques
- Liver Disease Diagnosis and Treatment
- Pharmacological Effects and Assays
- Biochemical effects in animals
- Circadian rhythm and melatonin
- Trace Elements in Health
- Adipokines, Inflammation, and Metabolic Diseases
- Animal Nutrition and Physiology
- Hormonal and reproductive studies
- Neuropeptides and Animal Physiology
- Muscle metabolism and nutrition
- Hypothalamic control of reproductive hormones
- Nutritional Studies and Diet
- Neurotransmitter Receptor Influence on Behavior
- Estrogen and related hormone effects
- Receptor Mechanisms and Signaling
- Obesity, Physical Activity, Diet
- Sirtuins and Resveratrol in Medicine
- Pancreatic function and diabetes
University of Maryland, College Park
2010-2019
Iowa State University
2013
University at Buffalo, State University of New York
1994
McMaster University
1993
University of Southern California
1992
University of Toronto
1992
University of California, Davis
1981-1991
Sansum Medical Clinic
1990
Florida State University
1980-1984
Mount Holyoke College
1981
Berries and other anthocyanin-rich treatments have prevented weight gain adiposity in rodent models of diet-induced obesity. Their efficacy may be explained by modulation energy substrate utilization. However, this effect has never been translated to humans. The objective study was evaluate the effects berry intake on use glucoregulation volunteers consuming a high-fat diet. Twenty-seven overweight or obese men were enrolled randomized, placebo-controlled crossover with two treatment...
Ten-week-old female obese and lean Zucker rats were given access to three separate macronutrient sources (casein, starch, lard) for 7 days. They then either adrenalectomized (ADX) or a sham operation. Rats assigned one of groups daily injection 0, 2, 10 mg corticosterone. continued select diet another 17 days, after which they killed, their blood was assayed corticosterone, adrenocorticotropin hormone (ACTH), insulin, glucose, triglyceride. Retroperitoneal parametrial fat depots excised...
Adult Otsuka Long-Evans Tokushima fatty (OLETF) rats lack functional cholecystokinin A (CCK-A) receptors, are diabetic, hyperphagic, and obese, have patterns of ingestion consistent with a satiety deficit secondary to CCK insensitivity. Because dietary fat potently stimulates release, we examined how modulates feeding in adult male OLETF their lean [Long-Evans (LETO)] controls. High-fat produced sustained overconsumption high-fat diet (30% corn oil powdered chow) over 3-wk period but not...
Male obese and lean Zucker rats were adrenalectomized (ADX) or sham-operated at 10 wk of age. Approximately 16 later, patterns food intake monitored by computer-interfaced top loading balances. Data collected from ADX before, during, after access to a corticosterone-supplemented saline solution (20 micrograms/ml). Although total during the precorticosterone treatment period was not different between sham controls, resulted in attenuation light cycle intake, primarily via decreased meal...
The increased prevalence of overweight and obesity in the United States during past three decades coincides with a trend sugar intake, especially fructose, leading to speculation that two trends may be linked. enzyme 11β‐hydroxysteroid dehydrogenase type 1 (11β‐HSD1), regulates intracellular tissue‐specific glucocorticoid levels, is adipose suppressed liver obese humans animals. Hexose‐6‐phosphate (H6PDH) colocalized 11β‐HSD1 generates nicotinamide adenosine dinucleotide phosphate, required...
Lean and obese Zucker fatty rats were adrenalectomized or sham operated at 10 wk of age. At 15 one-half each group was placed on a high-fat diet. 32 age the experiment ended. Several conclusions can be drawn about effects adrenalectomy, diets, their interaction in rat. First, adrenalectomy slowed weight gain both lean animals, although effect greater rats. Second, accelerated intact eating Third, attenuated associated with diet reduced body content fat protein animals fed low-fat Fifth,...
We examined serum leptin levels in a controlled feeding and alcohol ingestion study to elucidate potential mechanisms by which may affect cancer immunologically related health risks. A total of 53 healthy, nonsmoking postmenopausal women completed random-order, three-period crossover design each woman received zero (0 g alcohol), one (15 or two (30 alcohol) drinks per day. After accounting for differences body mass index, who consumed 15 30 day had 7.3% (95% confidence interval [CI] = 3.0%...
Experimental colitis was induced in rats by intrarectal infusion of trinitrobenzenesulfonic acid and ethanol. Colitis accompanied a large suppression food intake 3 days duration. The reduction effected through meal size, with no change frequency. Those same demonstrating approximately 70%-80% daily showed sham feeding. These data indicate that malaise alone is inadequate to explain the associated acute colitis. Rather, suggest eating results from an exaggerated postprandial satiety signal...