A5051500521- Gut microbiota and health
- Child Nutrition and Water Access
- Vibrio bacteria research studies
- Probiotics and Fermented Foods
- Antibiotic Resistance in Bacteria
- Clostridium difficile and Clostridium perfringens research
- Food Security and Health in Diverse Populations
- Autophagy in Disease and Therapy
- Microbial Metabolites in Food Biotechnology
- Fecal contamination and water quality
- melanin and skin pigmentation
- Genomics and Phylogenetic Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Prostate Cancer Diagnosis and Treatment
- Berberine and alkaloids research
- Mobile Health and mHealth Applications
- Aquaculture disease management and microbiota
- Calcium signaling and nucleotide metabolism
- Urinary Bladder and Prostate Research
- Nutrition, Health and Food Behavior
- Urinary Tract Infections Management
- Salmonella and Campylobacter epidemiology
- Antimicrobial Peptides and Activities
- Global Maternal and Child Health
- Environmental DNA in Biodiversity Studies
Soonchunhyang University
2022-2025
International Centre for Diarrhoeal Disease Research
2020-2024
Abstract Mycobacterium tuberculosis , a lethal pathogen in human history, causes millions of deaths annually, which demands the development new concepts drugs. Considering this fact, earlier research has explored anti-tuberculosis potential probiotic strain, Lactocaseibacillus rhamnosus PMC203, leading to subsequent focus on molecular mechanism involved its effect, particularly autophagy. In current study, immunoblotting-based assay exhibited remarkable expression autophagy marker LC3-II...
Abstract Background One of the most significant public health concerns in today’s world is persistent upsurge infections caused by multidrug resistant bacteria. As a result, clinicians are being forced to intervene with either less effective backup drugs or ones substantial side-effects. Colistin last resort antimicrobial agent for treatment multi-drug gram-negative Methods Escherichia coli (n = 65) isolated from street food 20), hand rinse 15), surface water 10), and healthy human stool 20)...
Abstract Mycobacterium tuberculosis ( M. tb ), the etiological agent of (TB), poses a severe challenge for public health and remains number one cause death as single infectious agent. There are 10 million active cases TB per year with 1.5 deaths, 2–3 billion people estimated to harbor latent infection. Moreover, emergence multi-drug-resistant (MDR), extremely-drug-resistant (XDR), recent totally drug-resistant (TDR) is becoming global issue that has fueled need find new drugs different from...
Abstract Background The Cholera Hospital-Based Intervention for 7 Days (CHoBI7) mobile health (mHealth) program was a cluster-randomized controlled trial of diarrhea patient households conducted in Dhaka, Bangladesh. Methods Patients were block-randomized to 3 arms: standard message on oral rehydration solution use; facility delivery CHoBI7 plus mHealth (no home visits); and 2 visits mHealth. primary outcome reported the past weeks collected monthly 12 months. secondary outcomes stunting,...
Despite the advancement in our understanding of cholera and its etiological agent, Vibrio cholerae, prevention treatment disease are often hindered due to rapid changes drug response pattern, serotype, major genomic islands namely, CTX-prophage, related genetic characteristics. In present study, V. cholerae (n = 172) associated with endemic Dhaka during years 2015-2021 were analyzed for phenotypic characteristics, including resistance patterns.Results revealed that strains belonged serogroup...
Numerous human pathologies, such as neoplasia, are related to particular bacteria and changes in microbiome constituents. To investigate the association between an imbalance of prostate carcinoma, gene functionality from tissues patients with high-grade tumor (HGT) low-grade (LGT) were compared utilizing next-generation sequencing (NGS) technology. The results showed abnormalities bacterial profiles HGT LGT specimens, indicating alterations make-up populations functionalities. specimens...
Abstract Background The excessive production and accumulation of melanin in the epidermal skin layer can result hyperpigmentation darkening. Current technologies for regulating are based on inhibiting biosynthesis. They have low effectiveness safety issues. Aims This study aimed to evaluate potential role Pediococcus acidilactici PMC48 as a probiotic strain medicines cosmetics treatment. Materials Methods Meanwhile, our research team has reported that P. isolated from sesame leaf kimchi...
The objective of the study was to investigate potential risk factors for growth faltering among children under 5 years age.We conducted a prospective cohort 553 from diarrhoea patient households in urban Dhaka, Bangladesh. Height and weight measurements were obtained at baseline 12-month follow-up. Caregivers young administered monthly questionnaire on household sociodemographic characteristics hygiene practices.Children with caregiver reports mouthing soil majority visits had significant...
Tuberculosis is a highly contagious disease caused by Mycobacterium tuberculosis, and the increase in antibiotic resistance threatens humankind. Therefore, there an urgent need to develop new anti-tuberculosis drugs that can overcome limitations of existing drugs. Here, we report effect microbiome therapeutic PMC205, strain Bacillus subtilis.
As NGS (next-generation sequencing) technology develops, metagenomics-based microbial ecology, that is, microbiome research, has recently led to the science of fermented food. Based on above technology, a study was conducted understand characteristics vinegar made from bokbunja, local crop in Gochang-gun, Korea. Physicochemical vinegar, organic acid analysis, community and electronic tongue analysis were explored while fermenting for 70 days under eight fermentation conditions according...
We investigated the environmental and individual-level risk factors for diarrheal disease among young children in slum areas of Dhaka, Bangladesh. A prospective cohort study was conducted 884 under 5 years age. Caregiver reports were collected on sociodemographic hygiene behaviors. Diarrhea surveillance data monthly based caregiver-reported diarrhea past 2 weeks during 12-month period. Unannounced spot checks household compound performed at 1, 3, 6, 9, 12 months after enrollment to check...
The aim of this study was to identify the exposure pathways fecal pathogens for a pediatric population living in urban slums Bangladesh. A total 252 soil, food, surface, and hand rinse samples were collected from pilot households with children less than 5 years age. All analyzed using IDEXX Quanti-Tray System (Colilert-18) enumerate indicator bacteria Escherichia coli. coli detected all soil play spaces (N = 46), 35% objects surfaces frequently put their mouths, 31% child food samples....
Abstract Background Despite the advancement in our understanding of cholera and its etiological agent, V. cholerae , prevention treatment disease are often hindered due to rapid changes drug response pattern, serotype, major genomic islands namely, toxin phage, related genetic characteristics. In present study, (n = 172) associated with endemic Dhaka during years 2015–2021 were analyzed for phenotypic characteristics, including resistance patterns. Results revealed that strains belonged...
Abstract Background Cholera can result in the expulsion of important microbiota from gut and death if left untreated. The disease transmits mainly via drinking water carrying Vibrio cholerae ; household contacts (HHC) cholera patients are at elevated risk during first week infection. profiles HHC-children Dhaka city slums were investigated before (day 0) after 8) delivery chlorinated as part major study ‘CHoBI7 trial (cholera-hospital-based intervention for 7 days)’. Result Results...
Xerosis, characterized by dry, rough skin, causes discomfort and aesthetic concerns, necessitating effective treatment. Traditional treatments often show limited efficacy, prompting the need for innovative therapies. This study highlights efficacy of microbiome therapeutic LP51, derived from a healthy vaginal microbiome, in improving xerosis. A double-blind clinical trial involving 43 subjects with dry inner arm skin compared effects 2.9% LP51 extract formulation to placebo over 4 weeks. The...
Abstract Cholera can result in the expulsion of important microbiota from gut and death if left untreated. The disease transmits mainly via drinking water carrying Vibrio cholerae ; household contacts (HHC) cholera patients are at elevated risk during first week infection. profiles HHC-children Dhaka city slums were investigated before (day 0) after 8) delivery chlorinated as part cholera-hospital-based intervention for 7 days (CHoBI7), a randomized controlled trial. Results sequencing...