A5005059553- Inflammatory Bowel Disease
- Microscopic Colitis
- Gastrointestinal motility and disorders
- Autoimmune and Inflammatory Disorders
- Pharmacological Effects of Natural Compounds
- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Congenital gastrointestinal and neural anomalies
- Intestinal and Peritoneal Adhesions
- Intraperitoneal and Appendiceal Malignancies
- Bioactive Compounds and Antitumor Agents
- Anorectal Disease Treatments and Outcomes
- Ovarian cancer diagnosis and treatment
- Appendicitis Diagnosis and Management
- Dye analysis and toxicity
- Biosimilars and Bioanalytical Methods
- Nutrition and Health in Aging
- Pathogenesis and Treatment of Hiccups
- Pelvic floor disorders treatments
- Diverticular Disease and Complications
- melanin and skin pigmentation
- Colorectal Cancer Screening and Detection
State Scientific Center of Coloproctology
2018-2025
Ministry of Health of the Russian Federation
2022
Aim . Current clinical recommendations accentuate current methods for the diagnosis and treatment of irritable bowel syndrome (IBS). Key points. IBS is a functional disorder manifested with recurrent, at least weekly, abdominal pain following attributes (any two leastwise): link to defecation, its frequency or stool shape. The symptoms are expected persist minimum three months in total six-month follow-up. Similar other gastrointestinal (GI) disorders, can be diagnosed basing on patient...
AIM : to evaluate the two-year survival of therapy with biosimilars ioftiximab and adalimumab in patients Crohn's disease (CD). PATIENTS AND METHODS: was assessed by primary medical records (electronic records) CD who started on or infliximab 2017-2019. Forty-nine received 39 were included study. The main clinical demographic data, laboratory tests (hemoglobin, leukocyte, platelet, albumin, C-reactive protein fibrinogen levels) instrumental checkup (ileocolonoscopy, intestinal ultrasound, CT...
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Hemorrhoidal disease is one ofthe most common pathologies anorectal region, its specific weight in the structure of diseases colon about 40%. Hemorrhoids are a socially significant disease, often found able-bodied population. The reason for development hemorrhoids, on hand, violation blood circulation cavernous corpuscles, due to which they increase and nodes form, other dystrophic changes ligamentous apparatus connection with gradually shift down begin fall out anal canal. One factors...
The review evaluates pathogenesis of intestinal fistulas in Crohn’s disease (CD). An idea the possible contribution microbiological and genetic factor is given. effect matrix metalloproteinases their tissue inhibitors also assessed. One most promising areas which can explain development CD epithelial-mesenchymal transition. Further research required to identify cause complicated CD, future will develop correct approaches pathogenetic therapy.
AIM: to evaluate the effectiveness of bowel cleansing before colonoscopy using enteral nutrition agent «Nutridrink» as single nutrient. MATERIALS AND METHODS: a prospective comparative study included 150 patients (83 females, aged 20-65 years), who underwent diagnostic colonoscopy. To assess quality Likert scale was used. Subjective assessment patients' comfort performed by on 10-point visual (from 0 - «excellent» 10 «extremely negative»). RESULTS: colon significantly better in got...
Introduction . Inflammatory bowel diseases are a group of chronic, immune-mediated unknown etiology. Etiotropic therapy IBD does not exist, all drugs used to treat have pathogenetic effect. In the treatment biologic is used. The most previously registered biologics anti-TNF-α. But, after expiration relevant patents, biosimilars appeared on market (analogs, comparable in quality already approved reference product). Materials and methods A retrospective study was conducted basis Ryzhikh...
Язвенный колит – аутоиммунное заболевание толстой кишки, проявляющееся развитием неспецифического воспаления его слизистой оболочки с обязательным поражением прямой кишки. Наиболее часто в клинической практике встречается левосторонний язвенный колит, легкая или среднетяжелая атака. Оптимальным способом лечения таких пациентов являются месалазины, однако применение препарата рН-зависимой оболочкой может быть ограничено связи большим разнообразием значений рН у воспалительными заболеваниями...
Melanosis coli is characteristic of patients with a long history constipation and the use laxatives – anthraquinone derivatives, which are quite prescribed by doctors independently. As rule, melanosis develops after 4–9 months taking drugs from this group most common in women older age group. Pathogenetically, characterized deposition pigment lamina propria mucous membrane, manifested pronounced dark coloration mucosa, depending on degree pigmentation colon, divided into three degrees. The...