A5101724412- Signaling Pathways in Disease
- Autophagy in Disease and Therapy
- Peroxisome Proliferator-Activated Receptors
- Calcium signaling and nucleotide metabolism
- Liver Disease Diagnosis and Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Health and Mental Health
- Medicinal Plant Pharmacodynamics Research
- Endoplasmic Reticulum Stress and Disease
- Pulmonary Hypertension Research and Treatments
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiac, Anesthesia and Surgical Outcomes
- Drug Transport and Resistance Mechanisms
- Traditional Chinese Medicine Analysis
China Pharmaceutical University
2025
Zunyi Medical University
2017-2021
Nanjing Traditional Chinese Medicine Hospital
2021
Pulmonary arterial hypertension (PAH) is an insidious and progressive disease that triggered by various cardiopulmonary diseases. Inflammation has important role in the progression of PAH. Osthole (Ost) a coumarin clear anti‑inflammatory properties. The present study aimed to investigate effects Ost on PAH, explore mechanism underlying this effect. Using monocrotaline (MCT)‑induced PAH rat model, were investigated. Rats subcutaneously administered single dose MCT (50 mg/kg) establish...
This study aimed to explore whether icarrin (ICA) can protect cardiomyocytes from hypertension-induced damage by inhibiting endoplasmic reticulum stress (ERS).Spontaneously hypertensive rats (SHRs) were orally administered water or ICA at 10, 20 and 40 mg/kg once daily for 12 weeks, Wistar-Kyoto (WKY) used as control. Changes in the growth blood pressure of assessed. Cardiac function was determined ultrasound left ventricle mass calculated. Myocardial tissue structure assessed haematoxylin...