Patricia A. Clark

ORCID: 0000-0003-1197-7389
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About
Contact & Profiles
Research Areas
  • Solar and Space Plasma Dynamics
  • Hemoglobin structure and function
  • Geophysics and Gravity Measurements
  • Mitochondrial Function and Pathology
  • Tuberculosis Research and Epidemiology
  • Ionosphere and magnetosphere dynamics
  • Geriatric Care and Nursing Homes
  • Birth, Development, and Health
  • Blood Coagulation and Thrombosis Mechanisms
  • Pneumonia and Respiratory Infections
  • Dementia and Cognitive Impairment Research
  • Cardiovascular and exercise physiology
  • Viral Infections and Vectors
  • Advanced Thermodynamics and Statistical Mechanics
  • Viral gastroenteritis research and epidemiology
  • Pregnancy and preeclampsia studies
  • Epigenetics and DNA Methylation
  • Intergenerational Family Dynamics and Caregiving
  • Mosquito-borne diseases and control
  • Infectious Diseases and Tuberculosis
  • Animal Disease Management and Epidemiology
  • NMR spectroscopy and applications
  • Patient-Provider Communication in Healthcare
  • Characterization and Applications of Magnetic Nanoparticles
  • Health and Medical Education

Parkview Health
2024

Henry Ford Hospital
2022

Weatherford College
2020

Academia Nacional de Medicina
2020

The University of Texas at Tyler
1997-2014

Texas Department of State Health Services
2012-2014

Cornell University
1957-2013

Michigan Department of Health and Human Services
2004-2009

Benjamin Rose Institute on Aging
2004-2008

American Association of Blood Banks
1999

Generation of Swine Flu As the newly emerged influenza virus starts its journey to infect world's human population, genetic secrets 2009 outbreak swine A(H1N1) are being revealed. In extensive phylogenetic analyses, Garten et al. (p. 197 , published online 22 May) confirm that eight elements virus, basic components encoded by hemagglutinin, nucleoprotein, and nonstructural genes originated in birds transferred pigs 1918. Subsequently, these formed a triple reassortant with RNA polymerase PB1...

10.1126/science.1176225 article EN Science 2009-05-23

10.1016/s0006-3495(85)83890-x article EN publisher-specific-oa Biophysical Journal 1985-02-01

Purpose: This demonstration evaluates the effects of integrating Alzheimer's Association care consultation service with health services offered by a large managed system. The primary hypothesis is that will decrease utilization, increase satisfaction care, and caregiver depression care-related strain. Secondary modifying-effects hypotheses posit intervention be intensified when patients have not received firm dementia diagnosis, more severe memory problems, caregivers use other in tandem...

10.1093/geront/43.1.73 article EN The Gerontologist 2003-02-01

This investigation evaluates effects of care consultation delivered within a partnership between managed health system and Alzheimer's Association chapter. Care is multi-component telephone intervention in which staff work with patients caregivers to identify personal strengths resources the family, plan, community. The primary hypothesis that will decrease utilization services improve psychosocial outcomes. A secondary modifying-effects posits benefits be greater for more severe memory...

10.1080/13607860310001613329 article EN Aging & Mental Health 2004-01-01

This analysis examines the ability of persons with mild to moderate dementia (MMSE scores 13—30 and/or a diagnosis) provide consistent and accurate information. Data come from interviews 213 (PWDs) their family caregivers (CG). Consistency was assessed by determining agreement between responses provided PWDs during two in-person interviews. Accuracy PWD CG responses. Overall, fact-based questions were in state-dependent items. Less impaired respondents more Among severe impairment, there no...

10.1177/1471301208093288 article EN Dementia 2008-08-01

As anticoagulant therapy has become more widespread and a greater knowledge been accumulated regarding the mode of action coumarin derivatives, problems arising from use different thromboplastin preparations have subjected to scrutiny. This paper presents an evaluation dependability significance types tissue in determination effects derivatives. The main difference between extracts seems be that brain factor VII-like activity. exact VII activity appears primary importance patients treated...

10.1161/01.cir.16.2.213 article EN Circulation 1957-08-01

We evaluated a strategy for preventing tuberculosis (TB) in communities most affected by it.In 1996, we mapped reported TB cases (1985-1995) and positive tuberculin skin test (TST) reactors (1993-1995) Smith County, Texas. delineated the 2 largest, densest clusters, identifying highest-incidence neighborhoods (180 square blocks, 3153 residents). After extensive community preparation, trained health care workers went door-to-door offering TST to all residents unless contraindicated....

10.2105/ajph.2012.300781 article EN American Journal of Public Health 2012-10-19

This qualitative case study focuses on 80 urban minority high school students enrolled in 2 California Career Academies, paying close attention to the cultural and institutional processes that impact their achievement. argues that, despite inequality, Academy model fosters optimism among low-income students. However, students' experiences differ within each academy context. Some structures are able promote positive student relations, whereas others simply reflect status quo. phenomenon is...

10.1207/s15327671espr0703_1 article EN Journal of Education for Students Placed at Risk (JESPAR) 2002-07-01

Summary A mathematical model based on finite differences was presented, which improved the accuracy of current modelling techniques during cooling period for conduction heating foods undergoing thermal processing. The surface heat transfer coefficient between can and fluid incorporated into difference equations, with a value 600 W m −2 K −1 chosen from literature confirmed by calculations temperature measurements correlation form Nu = f(GrxPr) n . Experimental results were obtained cylinder...

10.1111/j.1365-2621.1990.tb01128.x article EN International Journal of Food Science & Technology 1990-12-01

10.1016/s0006-3495(85)83856-x article EN publisher-specific-oa Biophysical Journal 1985-12-01

Distal-less 3 (Dlx3) is a homeobox factor that functions as placental-specific transcriptional regulator. Dlx3 null mice (−/−) have compromised placental development and do not survive in utero past embryonic day (E) 9.5. The current studies were undertaken to examine the expression of mouse placenta during gestation, determine whether was involved progesterone production. detectable at E8.5 but detected E9.5 with continuing diminished through E15.5. immuno-localization restricted labyrinth,...

10.1677/joe.1.06217 article EN Journal of Endocrinology 2005-08-01

The impulsive linear spin-down of a stably stratified Boussinesq fluid in circular cylinder is analyzed under the assumption that Prandtl number P = ν/κ small (ν kinematic viscosity, κ thermal diffusivity). nature process depends on ordering with respect to Ekman E. For < E ½ , similar an unstratified fluid. > for O (1). distinctive case ( ) detail. it shown N [Gt ] Ω, asymptotic state rigid rotation reached time order /Ω) 2 τ, where Brunt-Väisälä frequency, Ω angular velocity and τ...

10.1017/s0022112071002350 article EN Journal of Fluid Mechanics 1971-10-29

A linear theory is developed for the spin-up of a compressible fluid, stratified by spherical gravity field. Numerical results are obtained case strong stratification (Brunt–Väisälä frequency N much greater than rotation ω 0 ). The interior flow solved in terms set angular eigenfunctions which have been numerically. principal result that limited to layer adjacent boundary, thickness δ being order L (ω / ), where radius boundary. solution qualitatively similar found Holton (1965), Walin...

10.1017/s0022112071003033 article EN Journal of Fluid Mechanics 1971-01-15

Distribution of O2 within and among arterioles venules was determined in dog rat gracilis muscles with a cryospectrophotometric method. Saturation 40-microns not demonstrably different from saturation the aorta even when flow abnormally low. Arterioles greater than 40 microns ran parallel to venules. Measurements mathematical model indicate that diffusive shunting is negligible for typical separation distances between Most were 30 microns. In some venule segments less 15 an arteriole, 10...

10.1152/ajpheart.1991.261.6.h2031 article EN AJP Heart and Circulatory Physiology 1991-12-01

ABSTRACT Humans infected with West Nile virus (WNV) develop immunoglobulin M (IgM) antibodies soon after infection. The microtiter-based assays for WNV IgM antibody detection used by most state public health and reference laboratories utilize antigen isolated from Vero cells or recombinant envelope protein produced in COS-1 cells. Recombinant was to a capture enzyme immunoassay (EIA). A supplementary EIA using expressed Drosophila melanogaster S2 also developed. Both detected the sera of...

10.1128/cdli.11.4.651-657.2004 article EN Clinical and Vaccine Immunology 2004-07-01

10.1016/s0006-3495(83)84365-3 article EN publisher-specific-oa Biophysical Journal 1983-04-01

Objective. The goals of this study were to estimate seroprevalence prior hepatitis B infection among high-risk adolescents and determine the cost-effectiveness prevaccination immunity screening. Methods. authors computed a break-even level calculated from current vaccine administration costs. They then conducted core antibody using sera previously submitted for syphilis serology four-hundred adolescent adult clients sexually transmitted disease clinics. Finally, compared age group-specific...

10.1016/s0033-3549(04)50008-0 article EN Public Health Reports 2001-03-01

An investigation of the time development differential rotation produced by solar wind torque indicates that sun has a rapidly rotating core.

10.1126/science.164.3877.290 article EN Science 1969-04-18

Matrix metalloproteinases (MMPs) are enzymes that regulate extracellular matrix composition and contribute to cell migration. Microarray studies in mouse placenta suggested MMP-9 transcript abundance was dependent on distal-less 3 (Dlx3), a placental-specific transcriptional regulator; however, it not clear if this direct or indirect effect. Here we investigate mechanism(s) for Dlx3-dependent gene transcription gelatinase activity placental trophoblasts. Initial confirmed reduced explants...

10.1152/ajpcell.00205.2012 article EN AJP Cell Physiology 2013-05-09
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