Nan Lu

ORCID: 0000-0003-1204-1603
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About
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Research Areas
  • Plant Reproductive Biology
  • Plant Gene Expression Analysis
  • Horticultural and Viticultural Research
  • Genetic diversity and population structure
  • Genetic Mapping and Diversity in Plants and Animals
  • Plant biochemistry and biosynthesis
  • Plant Physiology and Cultivation Studies
  • Plant Molecular Biology Research
  • Medicinal plant effects and applications
  • Agriculture and Biological Studies
  • Photosynthetic Processes and Mechanisms
  • Plant tissue culture and regeneration
  • Insect Resistance and Genetics
  • Bioenergy crop production and management
  • Leaf Properties and Growth Measurement
  • Genetics and Plant Breeding
  • Plant Stress Responses and Tolerance
  • Chromosomal and Genetic Variations
  • Plant Virus Research Studies
  • Viral Infectious Diseases and Gene Expression in Insects
  • Forest Insect Ecology and Management
  • Plant Parasitism and Resistance
  • Plant Disease Resistance and Genetics
  • Lignin and Wood Chemistry
  • Transgenic Plants and Applications

Wuhan University
2006-2025

Zhongnan Hospital of Wuhan University
2025

University of North Texas
2016-2024

Renji Hospital
2024

Research Institute of Forestry
2017-2023

Chinese Academy of Forestry
2017-2023

State Forestry and Grassland Administration
2023

Affiliated Hospital of Jining Medical University
2019-2022

Shenyang Agricultural University
1989-2020

Beijing Forestry University
2014-2019

Proanthocyanidins (PAs), also known as condensed tannins, are plant natural products that beneficial for human and livestock health. As one of the largest grown crops in world, soybean (Glycine max) is widely used food animal feed. Many cultivated soybeans with yellow seed coats lack PAs or anthocyanins, although some cultivars have coloured contain these compounds. Here, we analyse transcriptional control PA anthocyanin biosynthesis soybean. Ectopic expression transcription factors (TFs)...

10.1111/pbi.13562 article EN cc-by-nc-nd Plant Biotechnology Journal 2021-02-05

Primary aldosteronism lateralization is critical for the treatment option. This study evaluated preoperative localization diagnostic efficiency of 68Ga-pentixafor positron emission tomography/computed tomography imaging, targeting C-X-C chemokine receptor type 4 in patients with primary and comparing adrenal venous sampling, current gold standard lateralization. Fifty underwent sampling imaging region separately. Patients determined by or adrenalectomy, followed pathologic diagnoses...

10.1016/j.surg.2025.109156 article EN cc-by-nc-nd Surgery 2025-02-07

Almost all C4 plants require the co-ordination of adjacent and fully differentiated cell types, mesophyll (M) bundle sheath (BS). The photosynthetic pathway operates through two distinct subtypes based on how malate is decarboxylated in BS cells; NAD-malic enzyme (NAD-ME) or NADP-malic (NADP-ME). diverse unique cell-specific molecular features M cells from separate independent lineages remain to be determined. We here provide an M/BS type-specific transcriptome data set monocot NAD-ME...

10.1093/jxb/erv553 article EN cc-by Journal of Experimental Botany 2016-02-19

Separate activities of anthocyanidin reductase generate epicatechin starter and extension units proanthocyanidins.

10.1126/sciadv.abg4682 article EN cc-by-nc Science Advances 2021-05-14

Anthocyanins and proanthocyanins (PAs) are two end products of the flavonoid biosynthesis pathway. They believed to be synthesized in endoplasmic reticulum then sequestered into vacuole. In Arabidopsis thaliana, TRANSPARENT TESTA 19 (TT19) is necessary for both anthocyanin PA accumulation. Here, we found that MtGSTF7, a homolog AtTT19, essential accumulation but not required Medicago truncatula. MtGSTF7 was induced by regulator LEGUME ANTHOCYANIN PRODUCTION 1 (LAP1), its tissue expression...

10.1093/jxb/erac112 article EN cc-by Journal of Experimental Botany 2022-03-12

Abstract Proanthocyanidins (PAs), flavonoid polymers involved in plant defense, are also beneficial to human health and ruminant nutrition. To date, there is little evidence for accumulation of PAs maize ( Zea mays ), although makes anthocyanins possesses the key enzyme PA pathway, anthocyanidin reductase (ANR). Here, we explore whether a functional biosynthesis pathway using combination analytical chemistry genetic approaches. The endogenous biosynthetic machinery preferentially produces...

10.1038/s41467-023-40014-5 article EN cc-by Nature Communications 2023-07-19

Proanthocyanidins (PAs), one of the most abundant natural polymers found in plants, are gaining increasing attention because their beneficial effects for agriculture and human health. The study PA biosynthesis has been active decades, progress drastically accelerated since discovery key enzymes such as Anthocyanidin Reductase (ANR), Leucoanthocyanidin (LAR), transcription factors Transparent Testa 2 (TT2) 8 (TT8) early 2000s. Scientists raised some compelling questions regarding about two...

10.3389/fpls.2024.1373975 article EN cc-by Frontiers in Plant Science 2024-03-26

Morus alba L. is an important tree species planted widely in China because of its economic value. In this report, we investigated the influence two arbuscular mycorrhizal fungal (AMF) species, Glomus mosseae and intraradices, alone together, on growth M. seedlings under greenhouse conditions. The parameters physiological performance were evaluated 90 days after colonization with fungi. significantly affected by AMF species. taller, had longer roots, more leaves a greater biomass than...

10.3390/f6030734 article EN Forests 2015-03-16

Clones of Catalpa bungei and fargesii f. duclouxii were studied over several years in central China to explore genetic variation growth traits identify clones high wood yield stability. The parameters for height, diameter at breast height (DBH), stem volume clones, estimated. effect clone × year on the increment two species was analyzed by genotype environment (GGE) biplot methods. Significant differences among between found. C. exceeded that after 4 years. Furthermore, from 5th year,...

10.3390/f10010057 article EN Forests 2019-01-12

Catalpa bungei is an important tree species used for timber in China and widely cultivated economic ornamental purposes. A high-density linkage map of C. would be efficient tool not only identifying key quantitative trait loci (QTLs) that affect traits, such as plant growth leaf but also other genetic studies.Restriction site-associated DNA sequencing (RAD-seq) was to identify molecular markers construct a map. Approximately 280.77 Gb clean data were obtained after sequencing, total,...

10.1186/s12870-019-2207-y article EN cc-by BMC Plant Biology 2019-12-01

Catalpa bungei is an economically important tree with high-quality wood and highly valuable to the study of formation. In this work, xylem microstructure C. tension (TW) was observed, we performed transcriptomics, proteomics Raman spectroscopy TW, opposite (OW) normal (NW). The results showed that there no obvious gelatinous layer (G-layer) in TW secondary wall deposition reduced compared OW NW. We found most differentially expressed mRNAs proteins were involved carbohydrate polysaccharide...

10.3390/ijms21051686 article EN International Journal of Molecular Sciences 2020-03-01

Plants have evolved different routes for the synthesis and assembly of building blocks proanthocyanidins.

10.1093/plphys/kiac274 article EN cc-by-nc-nd PLANT PHYSIOLOGY 2022-06-13

Abstract Two new flavonoids, acanthophorin A (1) and B (2), along with three known compounds tiliroside (3), (‐)‐catechin (4) quercetin (5) were isolated from the red alga Acanthophora spicifera . The structures of 1 2 determined to be kaempferol 3‐ O ‐α‐ L ‐fucopyranoside (2) by spectroscopic methods. Both showed significant antioxidant activity.

10.1002/cjoc.20010191116 article EN Chinese Journal of Chemistry 2001-11-01

Etiolation (a process of growing plants in partial or complete absence light) promotes adventitious root formation tetraploid black locust (Robinia pseudoacacia L.) cuttings. We investigated the mechanism underlying how etiolation treatment and assessed global transcriptional changes after treatment. Solexa paired-end sequencing complementary DNAs (cDNAs) from control (non-etiolated, NE) etiolated (E) samples resulted 107,564 unigenes. In total, 52,590 transcripts were annotated 474 (211...

10.3390/genes8120345 article EN Genes 2017-11-24

The tree species Pinus tabulaeformis Carr. (P. tabulaeformis) is commonly planted in China due to its economic and ecological value. In order identify one or more ectomycorrhizal (ECM) fungal for future P. afforestation, we investigated the effects of five ECM species: Laccaria laccata, Boletus edulis, Gomphidius viscidus, Suillus grevillei, luteus on growth seedlings under greenhouse conditions. parameters were evaluated 90 days following colonisation. majority significantly affected by...

10.3390/f7120316 article EN Forests 2016-12-14

Adverse events in platinum-based chemotherapy for patients with advanced non-small cell lung cancer (NSCLC) are major challenges. In this study, we investigated the role of p53 and MDM2 genes predicting adverse NSCLC treated chemotherapy. Specifically, examined p. Pro72Arg (rs1042522), c.14 + 309T>G (rs2279744) c.- 461C > G (rs937282) polymorphisms using PCR-based restriction fragment length polymorphism (RFLP) 444 patients. We determine that 309T was significantly associated severe...

10.4161/15384047.2014.956599 article EN Cancer Biology & Therapy 2014-10-29

Caffeic acid O-methyltransferase (COMT) is an important protein that participates in lignin synthesis and associated with the ratio of G-/S-type plants. COMTs are wood properties forest trees; however, little known about COMT family Catalpa bungei , a valuable timber tree species China . We performed comprehensive analysis genes C. genome by describing gene structure phylogenetic relationships each member using bioinformatics-based methods. A total 23 putative were identified conserved...

10.7717/peerj.6520 article EN cc-by PeerJ 2019-03-14

DnaJs are the common molecular chaperone proteins with strong structural and functional diversity. In recent years, only several DnaJ family members have been found to be able regulate leaf color, it remains explored whether there other potential that also this character. Here, we identified 88 putative from Catalpa bungei, classified them into four types according their domain. Gene-structure analysis revealed each member of CbuDnaJ had same or similar exon-intron structure. Chromosome...

10.3389/fpls.2023.1116063 article EN cc-by Frontiers in Plant Science 2023-02-23

Summary Fragaria vesca was transformed with a transposon tagging construct harbouring amino terminally deleted maize transposase and EGFP ( Ac element), NPTII, CaMV 35S promoter (P35S) driving mannopine synthase (Pmas) Ds element). Of 180 primary transgenics, 48 were potential launch pads, 72 multiple insertions or chimaeras, 60 exhibited somatic transposition. T 1 progeny of 32 putative pads screened by multiplex PCR for Evidence germ‐line transposition occurred in 13 pads; however, the...

10.1111/j.1467-7652.2012.00728.x article EN other-oa Plant Biotechnology Journal 2012-07-31

Sophora moorcroftiana is a perennial leguminous low shrub endemic to the Yarlung Zangbo River basin in Tibet with irreplaceable economic and ecological value. To determine drivers of evolution this species, 225 individuals belonging 15 populations from different geographic locations were sampled, population genetics was studied using high-throughput genotyping-by-sequencing (GBS). Based on genetic diversity analysis, phylogenetic principal component structure natural clustered into following...

10.7717/peerj.9609 article EN cc-by PeerJ 2020-08-06
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