A5062114684- Pregnancy and preeclampsia studies
- Advanced oxidation water treatment
- Advanced Photocatalysis Techniques
- Cancer Genomics and Diagnostics
- TiO2 Photocatalysis and Solar Cells
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Extracellular vesicles in disease
- Gut microbiota and health
- Chemical Synthesis and Characterization
- PARP inhibition in cancer therapy
- Radioactive element chemistry and processing
- Prostate Cancer Diagnosis and Treatment
- DNA Repair Mechanisms
- MicroRNA in disease regulation
- Tryptophan and brain disorders
- Bladder and Urothelial Cancer Treatments
- Diet and metabolism studies
- Animal Disease Management and Epidemiology
- Urinary and Genital Oncology Studies
- Pharmacological Effects of Natural Compounds
- Circular RNAs in diseases
- Extraction and Separation Processes
- Traditional Chinese Medicine Studies
- Clinical practice guidelines implementation
Fuzhou University
2024-2025
Dalian Medical University
2023-2025
Gannan Medical University
2025
Hangzhou DAC Biotech (China)
2022-2024
Affiliated Zhongshan Hospital of Dalian University
2023
First Affiliated Hospital of Gannan Medical University
2023
Guangdong Provincial People's Hospital
2013
Abstract Background Interindividual variation characterizes the relief experienced by constipation-predominant irritable bowel syndrome (IBS-C) patients following linaclotide treatment. Complex bidirectional interactions occur between gut microbiota and various clinical drugs. To date, no established evidence has elucidated linaclotide. We aimed to explore impact of on identify critical bacterial genera that might participate in efficacy. Methods IBS-C were administered a daily dose 290 µg...
Large-scale extraction of uranium from seawater (UES) is considered to be an important way solve the nuclear fuel shortage, and development highly efficient selective adsorbents a key factor in realizing UES. In this work, Schiff base-conjugated amidoxime modificated porous organic polymers (OPA-PPA-AO) were synthesized by aldehyde-amine condensation hydroxylamine reactions for adsorption uranium. OPA-PPA-AO has excellent selectivity high capacity, with 53 times capacity vanadium, maximal...
Background Prostate cancer (PCa) in the transition zone (TZ) is uncommon and often poses challenges for early diagnosis, but its genomic determinants therapeutic vulnerabilities remain poorly characterized. Methods Tumor mutational landscape was characterized nine patients with TZ PCa, identifying somatic variants through whole-exome sequencing (WES). Novel candidate relevant to driver gene were selected using rare-variant burden analysis. Kaplan-Meier curves log-rank testing Cox regression...
Osteosarcoma, an aggressive bone malignancy predominantly affecting children and adolescents, is characterized by a poor prognosis high mortality rates. The development of reliable prognostic tools critical for advancing personalized treatment strategies. However, identifying robust gene signatures to predict osteosarcoma outcomes remains significant challenge. In this study, we analyzed expression data from 138 samples across two multicenter cohorts identified 14 consensus...
Objective: To analyze the correlation between urinary albumin/creatinine ratio (ACR) and 24-hour microalbumin (UMA) evaluate predictive value of ARC for early diabetic nephropathy. Methods: A total 368 patients with type 2 diabetes mellitus were retrospectively collected. Early nephropathy was defined as 24h UMA 30~<300 mg/24h. The ACR 24hUMA, area under receiver operating characteristic (ROC) curve in diagnosis calculated. Gender, age, course disease, fasting venous blood glucose,...
Background: The association between misfolded proteins presented in the urine of pregnant women and pregnancy outcomes associated with early-onset pre-eclampsia (PE) remains unclear. This study aimed to investigate this examine predictive value urinary congophilia prognostication patient group Chinese population. Materials Methods: included 1,397 patients, which 46, 147, 8 patients had gestational hypertension, PE, chronic respectively, 1,196 were healthy controls undergoing CapCord test for...
Background Preeclampsia (PE) is one of the most common hypertensive diseases, affecting 2%-8% all pregnancies. The high maternal and fetal mortality rates PE are due to a lack early identification affected pregnant women that would have led closer monitoring care. Recent data suggest misfolded proteins might be promising biomarker for prediction, which can detected in urine samples according their congophilia (aggregated) characteristic. Objective main purpose this trial evaluate value...
The photocatalytic activation of the persulfate process has been considered a promising water treatment technology because generation highly oxidative sulfate radical (•SO4−) for organic pollutant mineralization. However, sluggish diffusion •SO4− from catalyst surface into bulk solution severely limits availability and utilization. Herein, we presented defective carbon nitride (DCN) as efficient peroxymonosulfate-activation coupling nonradical aggregation-radical tailored electronic...
Objective To explore the effect of clinical pathway on health education patients with nasopharyngeal carcinoma,so as to establish optimal model education.Methods Through development nursing pathway,totals 80 cases were randomly divided into control group (n =40)and experimental =46).Patients in received routine education,while according pathway.Then,patients' knowledge and satisfaction quality was compared between two groups.Results The compliance rate master (97.83％ vs 45.00％) degree...
<sec> <title>BACKGROUND</title> Preeclampsia (PE) is one of the most common hypertensive diseases, affecting 2%-8% all pregnancies. The high maternal and fetal mortality rates PE are due to a lack early identification affected pregnant women that would have led closer monitoring care. Recent data suggest misfolded proteins might be promising biomarker for prediction, which can detected in urine samples according their congophilia (aggregated) characteristic. </sec> <title>OBJECTIVE</title>...
Objective To evaluate the effect of Danqi Yishen decoction on diabetes mellitus(DM) and its influence proteinuria. Methods 150 DM patients were randomly selected, they divided into two groups according to digital table, 75 cases in each group.The control group was given western medicine, study treated by decoction.The treatment efficacy, blood serum creatinine(Cr), 24h urine protein, urea nitrogen(BUN) fasting glucose(FBG) before after compared between groups. Results The total...
Background: Aggregates of misfolded proteins, which previously were shown to be related preeclampsia, may used as diagnostic marker by testing patients' urine. We developed an easy-to-perform POCT (point care test) method for detecting urinary proteins we termed "Misfolded Protein Test", and validated its utility in a large clinically relevant cohort.