James S. Khan

ORCID: 0000-0003-1210-7545
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About
Contact & Profiles
Research Areas
  • Anesthesia and Pain Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Pain Management and Opioid Use
  • Musculoskeletal pain and rehabilitation
  • Pediatric Pain Management Techniques
  • Spine and Intervertebral Disc Pathology
  • Hemodynamic Monitoring and Therapy
  • Pain Mechanisms and Treatments
  • Pain Management and Placebo Effect
  • Health and Medical Research Impacts
  • Non-Invasive Vital Sign Monitoring
  • Cardiac Health and Mental Health
  • Shoulder Injury and Treatment
  • Nerve Injury and Rehabilitation
  • Hip and Femur Fractures
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Anesthesia and Sedative Agents
  • Pain Management and Treatment
  • Heart Rate Variability and Autonomic Control
  • Nausea and vomiting management
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Diversity and Career in Medicine
  • Acupuncture Treatment Research Studies
  • EEG and Brain-Computer Interfaces
  • Cancer survivorship and care

University of Toronto
2016-2025

Mount Sinai Hospital
2019-2025

Sinai Health System
2023-2024

University of California, San Francisco
2024

University Health Network
2014-2023

National Hospital for Neurology and Neurosurgery
2021

University College London
2021

McMaster University
2014-2019

Population Health Research Institute
2014-2019

Impact
2019

Tobacco smoking is associated with adverse health effects, and its relationship to pain complex. The longitudinal effect of on patients attending a tertiary management center not well established. Using the Collaborative Health Outcomes Information Registry Stanford Pain Management Center from 2013 2017, we conducted propensity-weighted analysis determine independent effects chronic pain. We adjusted for covariates including age, sex, body mass index, depression anxiety history, ethnicity,...

10.1097/j.pain.0000000000001631 article EN Pain 2019-05-28

Perioperative hypotension is associated with cardiovascular events in patients having noncardiac surgery. It unknown if the severity of preexisting coronary artery disease determines susceptibility to risks perioperative hypotension.In this retrospective exploratory analysis a substudy an international prospective blinded cohort study, 955 45 yr age or older history risk factors for underwent computed tomographic angiography before elective inpatient The authors evaluated potential...

10.1097/aln.0000000000002654 article EN Anesthesiology 2019-03-17

Chronic postsurgical pain is a common complication of surgery. The role psychologic risk factors like depression and anxiety substantially understudied in cardiac This study sought to identify perioperative associated with chronic at 3, 6, 12 months after authors hypothesize that baseline vulnerabilities have negative influence on pain.The prospectively collected demographic, psychologic, cohort 1,059 patients undergoing surgery the Toronto General Hospital between 2012 2020. Patients were...

10.1097/aln.0000000000004621 article EN Anesthesiology 2023-05-16

Objective Four sets of eight audible alarms matching the functions specified in IEC 60601-1-8 were designed using known principles from auditory cognition with intention that they would be more recognizable and localizable than those currently standard. Background The associated 60601-1-8, a global medical device standard, are to difficult learn retain, there have been many calls update them. There design might form basis readily alarms. is also scope for improvement localizability existing...

10.1177/0018720817712004 article EN Human Factors The Journal of the Human Factors and Ergonomics Society 2017-06-02

Background The purpose of this study was to determine the incidence, characteristics, impact, and risk factors associated with persistent incisional pain. hypothesis that patient demographics perioperative interventions are Methods This a secondary analysis an international prospective cohort from 2012 2014. included patients who were 45 yr age or older underwent major inpatient noncardiac surgery. Data collected perioperatively at 1 after surgery assess for development pain (pain present...

10.1097/aln.0000000000003951 article EN Anesthesiology 2021-09-09

BACKGROUND: Understanding the association of acute pain intensity and opioid consumption after cardiac surgery with chronic postsurgical (CPSP) can facilitate implementation personalized prevention measures to improve outcomes. The objectives were (1) examine daily mg morphine equivalent dose (MME/day) trajectories surgery, (2) identify factors associated trajectories, (3) assess whether are risk for CPSP. METHODS: Prospective observational cohort study design conducted between August 2012...

10.1213/ane.0000000000006848 article EN Anesthesia & Analgesia 2024-01-31

There are growing numbers of adults with Duchenne Muscular Dystrophy living well into their fourth decade. These patients have complex medical needs that to date not been addressed in the International standards care. We sought create a consensus based standard care through series multi-disciplinary workshops specialists from wide range clinical areas: Neurology, Cardiology, Respiratory Medicine, Gastroenterology, Endocrinology, Palliative Care Rehabilitation, Renal, Anaesthetics and...

10.3233/jnd-200609 article EN other-oa Journal of Neuromuscular Diseases 2021-09-07
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