Hongjiao Wang

ORCID: 0000-0003-1221-5482
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About
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Research Areas
  • Ferroptosis and cancer prognosis
  • RNA modifications and cancer
  • Cancer-related gene regulation
  • interferon and immune responses
  • Inflammasome and immune disorders
  • Endoplasmic Reticulum Stress and Disease
  • Viral gastroenteritis research and epidemiology
  • Oral health in cancer treatment
  • Immunotherapy and Immune Responses
  • Immune Response and Inflammation
  • Nutrition and Health in Aging
  • RNA regulation and disease
  • Epigenetics and DNA Methylation
  • Dysphagia Assessment and Management

Qilu Hospital of Shandong University
2024-2025

Shandong Institute of Food and Drug Inspection
2024

Shandong University
2024

Xiamen University
2023

Abstract The function of Family With Sequence Similarity 83, Member A (FAM83A) in lung squamous cell carcinoma (LUSC) is largely unknown. Here, we detected its prognostic and regulation roles LUSC. Bioinformatics methods were applied initially to predict the expression level value FAM83A mRNA In vitro experiments, such as western blot, colony formation viability assay, lipid Reactive oxygen species (ROS), malondialdehyde (MDA), reduced glutathione (GSH)/oxidized disulfide (GSSG),...

10.1038/s41420-024-02101-4 article EN cc-by Cell Death Discovery 2024-07-20

<title>Abstract</title> <bold>Background</bold> Oral nutritional supplements (ONS) play a critical role in improving radiotherapy’s clinical outcomes. This study assessed the correlation between knowledge, attitude, and practice (KAP) on ONS malnutrition risk of tumor patients during peri-radiotherapy period. <bold>Methods</bold> was multicenter cross-sectional survey Shandong, China. The period completed KAP questionnaire. Univariable / multivariable logistic regression analyses status were...

10.21203/rs.3.rs-6139810/v1 preprint EN cc-by Research Square (Research Square) 2025-03-13

The formation of germinal centers (GCs) is crucial for humoral immunity and vaccine efficacy. Constant stimulation through microbiota drives the constitutive GCs in Peyer's patches (PPs), which generate B cells that produce antibodies against gut antigens derived from commensal bacteria infectious pathogens. However, molecular mechanism regulates this persistent process poorly understood. We report Ewing Sarcoma Breakpoint Region 1 (EWSR1) a brake to GC generation immunoglobulin G (IgG)...

10.1084/jem.20221483 article EN cc-by-nc-sa The Journal of Experimental Medicine 2023-04-25

<title>Abstract</title> Background FAM83A function in LUSC is largely unknown. We detected its prognosis and regulation role LUSC. Methods The bioinformatics methods were performed initially to predict the expression level prognostic value of mRNA In vitro experiments, such as western blot, colony formation cell viability assay, lipid ROS, MDA GSH/GSSG 4-HNE assay used for mechanism validation. Results from TCGA Oncomine databases revealed that was significantly higher than normal lung...

10.21203/rs.3.rs-3866369/v1 preprint EN cc-by Research Square (Research Square) 2024-02-02

Background: FAM83A function in LUSC is largely unknown. We detected its prognosis and regulation role LUSC.Methods: The bioinformatics methods were performed initially to predict the expression level prognostic value of mRNA LUSC. Electron microscope analysis, western blot, colony formation cell viability assay, lipid ROS, MDA GSH/GSSG 4-HNE assay used for mechanism validation.Results: Results from TCGA Oncomine databases revealed that was significantly higher than normal lung tissue. GEO...

10.2139/ssrn.4731123 preprint EN 2024-01-01
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