A5015771566- Molecular Sensors and Ion Detection
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metal complexes synthesis and properties
- Diverse academic and cultural studies
- DNA and Nucleic Acid Chemistry
- Supramolecular Chemistry and Complexes
- Lanthanide and Transition Metal Complexes
- Luminescence and Fluorescent Materials
- Crystallography and molecular interactions
- Architecture and Computational Design
- Analytical Chemistry and Sensors
- Porphyrin and Phthalocyanine Chemistry
- Management, Economics, and Public Policy
- Nematode management and characterization studies
- Advanced biosensing and bioanalysis techniques
- Multisensory perception and integration
- Electrochemical Analysis and Applications
- Design Education and Practice
- Metal-Organic Frameworks: Synthesis and Applications
- Cultural Industries and Urban Development
- Photodynamic Therapy Research Studies
- Dendrimers and Hyperbranched Polymers
- Nanoplatforms for cancer theranostics
- Color perception and design
University of Florence
2015-2024
Polytechnic University of Turin
2014-2024
University of Regensburg
2024
Ospedale Vito Fazzi
2023
ORCID
2021
Centro di Riferimento Oncologico
2019
Polo d’Innovazione di Genomica
2014
University of Bari Aldo Moro
1976-2012
Universitat de València
1995-2008
Istituto Nazionale di Fisica Nucleare, Sezione di Cagliari
2008
Direct air capture (DAC) is an emerging technology that can help limit the global temperature rises, as it has potential to contrast dispersed CO2 emissions coming from transport and heating cannot be captured with traditional CCS methods. Although recent improvements are bringing DAC closer commercial feasibility, obstacle its diffusion high regeneration energy required by most common liquid sorbents, Na or K hydroxides. To develop efficient more sustainable in this screening study, several...
The ligand [30]aneN(6)O(4) (L1) binds two Zn(II) in aqueous solution. stability constants of the L1 complexes have been determined at 308.1 K by means potentiometric measurements. Dinuclear monohydroxo [Zn(2)L1OH](3+) and dihydroxo [Zn(2)L1(OH)(2)](2+) are formed solution from neutral to alkaline pH. kinetics promoted hydrolysis p-nitrophenyl acetate (NA) was studied. Both hydroxo species promote 298.1 with second-order kinetics. activity these NA is similar that found for mononuclear...
The interactions of phosphate and pyrophosphate anions with polyammonium cations deriving from 14 polyamines (five polyazacycloalkanes, four polyazacyclophanes, five acyclic polyamines) in aqueous solution have been studied by means potentiometric, microcalorimetric, NMR measurements solution. Very stable 1:1 receptor-to-anion complexes are formed. stability trends such not strictly determined electrostatic forces, hydrogen bond being considerable importance the complex formation,...
Is there a new material for use in jewelry, matching gold and precious stones, capable of maintaining the same perception “preciousness” but that is also more sustainable, ethical, inexpensive? This article deals with case study within European EcoDesign Network research project, aimed at investigating how sustainable design can help prestigious companies pinpoint materials creation focusing on environmentally friendly opportunities while preserving their market position target audience....
The CO2 uptake by single 2-amino-2-methyl-1-propanol (AMP) and its blends with 2-(ethylamino)ethanol (EMEA) or N-methyl-2,2′-iminodiethanol (MDEA) has been investigated in both aqueous nonaqueous solutions, compared 2-aminoethanol (MEA), the most used sorbent carbon capture storage (CCS) processes. loading capacity, rate of absorption, heat absorption have experimentally determined for all amine solutions. 13C NMR analysis allowed identification carbonated species formed solution evaluation...
Ruthenium(II) polypyridyl complexes (RPCs) are gaining momentum in photoactivated chemotherapy (PACT), thanks to the possibility of overcoming classical reliance on molecular oxygen photodynamic therapy while preserving selective drug activation by using light. However, notwithstanding intriguing perspectives, translation such an approach development new antimicrobials has been only barely considered. Herein, MTZH-1 and MTZH-2, two novel analogues metronidazole (MTZ), a mainstay treatment...
The clinical translation of photosensitizers based on ruthenium(II) polypyridyl complexes (RPCs) in photodynamic therapy cancer faces several challenges. To address these limitations, we conducted an investigation to assess the potential a cubosome formulation stabilized water against coalescence utilizing polyphosphoester analog Pluronic F127 as stabilizer and loaded with newly synthesized RPC-based photosensitizer [Ru(dppn)
The synthesis of the new alcohol-pendant macrocycle 4-(2-hydroxyethyl)-1,4,7,16,19,22-hexaaza-10,13,25,28-tetraoxacyclotriacontane (L2) is reported. This ligand contains two different triamine moieties, one them bearing an ethanolic sidearm. L2 binds Zn(II) ions in aqueous solution. stability constants complexes have been determined at 298.1 and 308.1 K by means potentiometric measurements. Besides a [Zn2L2]4+ species, deprotonated [Zn2(L2-H)]3+ complex hydroxo [Zn2(L2-H)(OH)]2+ are formed...
Solutions containing Zn(II) and Cu(II) complexes with [15]aneN(3)O(2) rapidly adsorb atmospheric CO(2) to give {[ZnL](3)(&mgr;(3)-CO(3))}.(ClO(4))(4) (2) {[CuL](3)(&mgr;(3)-CO(3))}.(ClO(4))(4) (4) complexes. The crystal structures of both have been solved (for 2, space group R3c, a, b = 22.300(5) Å, c 17.980(8) V 7743(4) Å(3), Z 6, R 0.0666, R(w)(2) 0.1719; for 4, 22.292(7) 10.096(8) 7788(5) 0.0598, 0.1611), the spectromagnetic behavior 4 has studied. In compounds a carbonate anion triply...
A chiral ditopic polyammonium receptor featuring two [9]aneN3 moieties separated by a (S)-BINOL linker is able to selectively bind and sense in water (S,S)-tartaric acid over its (R,R)/meso forms.
Thermodynamic parameters (ΔG°, ΔH°, TΔS°), obtained by means of potentiometric and isothermal titration calorimetry (ITC) methods, for the binding equilibria involving anions high negative charge, like SO42–, SeO42–, S2O32– Co(CN)63–, nitroso-amino-pyrimidine receptors in water suggested that anion−π interactions furnish a stabilization about −10 kJ/mol to free energy association. These are almost athermic favored large entropic contributions which likely due reduced hydrophobic pyrimidine...
Methylene blue (MB) can be employed as a photo-activatable antimicrobial drug in photodynamic therapy (PDT) due to its ability release oxygen free radicals upon photo-activation. However, poor penetrate bacterial cell walls and biofilms limits activity. To overcome these limitations, we propose some formulations of MB based on different cationic liposomes. The liposome-MB systems were characterized using dynamic light scattering (DLS), zeta potential analysis UV-visible spectroscopy. Their...
Ligands L1 and L2, consisting of a tetrazine ring decorated with two morpholine pendants different lengths, show peculiar anion-binding behaviors. In several cases, even the neutral ligands, in addition to their protonated HL+ H2L2+ (L = L2) forms, bind anions such as F–, NO3–, PF6–, ClO4–, SO42– form stable complexes water. The crystal structures H2L1(PF6)2·2H2O, H2L1(ClO4)2·2H2O, H2L2(NO3)2, H2L2(PF6)2·H2O, H2L2(ClO4)2·H2O that anion−π interactions are pivotal for formation these...
Abstract A comparative study between two novel, highly water soluble, ruthenium(II) polypyridyl complexes, [Ru(phen) 2 L ′] and Cu(II) ( ‐Cu II ), containing the polyaazamacrocyclic unit 4,4′‐(2,5,8,11,14‐pentaaza[15])‐2,2′‐bipyridilophane ′), is herein reported. interact with calf‐thymus DNA efficiently cleave plasmid when light‐activated. They also possess great penetration abilities photo‐induced biological activities, evaluated on an A375 human melanoma cell line, being most effective....
Human ferritin platforms containing Ru( ii )-polypyridyl-based photosensitizers effectively target cancer cells and provide cytotoxic effects upon light-activation.
The luminescence emission of a new dipyridyl-containing Eu(III) cryptate complex is modulated by pH, due to protonation the polyamine chain strategically inserted
The co-ordination properties toward Na+, Ca2+, Zn2+, Cu2+ and Gd3+ of six ligands containing pendant functionalities attached to the common 1,4,7,10-tetraazacyclododecane macrocyclic ring have been studied by means potentiometric microcalorimetric methods. Stability constants for 1,4,7,10-tetra(methylcarbamoylmethyl) ligand (DTMA), new 10-(2-hydroxypropyl) 1,4,7-tri(2-hydroxymethylacetic acid) (HPDO3A-3HM) (DO3A-3HM) are reported first time, while analogous data remaining redetermined under...
A new polyammonium receptor is able to selectively recognise and sense ATP among triphosphate nucleotides, thanks ATP-induced quantitative quenching of its fluorescence emission.
The hexapeptide Ser-Gly-Ala-Gly-Lys-Thr has been synthesized and characterized. It was designed as a minimal soluble peptide that would be likely to have the phosphate-binding properties observed in P-loops of proteins bind β-phosphate GTP or ATP. such is bound by combination side chain ε-amino group lysine residue plus concavity formed successive main NH groups called nest, which favored glycines. shown HPO(4) (2-) strongly at neutral pH. affinities various ionized species phosphate are...