- Adrenal and Paraganglionic Tumors
- Pituitary Gland Disorders and Treatments
- Sexual Differentiation and Disorders
- Neuroendocrine Tumor Research Advances
- Growth Hormone and Insulin-like Growth Factors
- Pancreatic and Hepatic Oncology Research
- Diabetes Treatment and Management
- Hormonal Regulation and Hypertension
- Neurofibromatosis and Schwannoma Cases
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Parathyroid Disorders and Treatments
- Hormonal and reproductive studies
- Tumors and Oncological Cases
- Neuroblastoma Research and Treatments
- Diabetes and associated disorders
- Metabolism, Diabetes, and Cancer
- Teratomas and Epidermoid Cysts
- Bone health and treatments
- Sperm and Testicular Function
- Medical Imaging and Pathology Studies
King Edward Memorial Hospital and Seth G.S. Medical College
2020-2021
Abstract Context Data are limited regarding prevalence, predictors, and mechanisms of persistent hypogonadotropic hypogonadism (HH) in males with a macroprolactinoma who achieve normoprolactinemia on dopamine-agonist therapy. None the previous studies provide cutoffs to predict achievement eugonadism. Objective The objective this work is evaluate prevalence HH its determinants men cabergoline monotherapy. Design Setting This retrospective study prospective cross-sectional evaluation took...
Most common incidentally detected sellar-suprasellar region (SSR) masses are pituitary adenomas, followed by craniopharyngioma, rathke's cleft cyst, hypophysitis, and meningioma. Besides these, certain unusual SSR lesions can sometimes present as diagnostic challenges, where diagnosis is often made post-operatively on histopathology, the pre-operative suspicion of which might have influenced management strategies. Series describing such few.To clinical, biochemical, radiological...
Abstract Objective To report clinical, hormonal and structural effects of CYP11B1 pathogenic variations in Indian patients with 11β‐hydroxylase deficiency (11βOHD) find criteria that accurately distinguish 11βOHD from 21α‐hydroxylase (21OHD). Design Retrospective record review genetically diagnosed 11βOHD. Patients Measurements Clinical features, parameters at diagnosis (by immunoassay) recent follow‐up 13 proven managed our centre were retrospectively reviewed. ACTH‐stimulated serum adrenal...
Abstract Context Conventional fractionated radiotherapy (CRT) achieves control of pathological hypercortisolism in 75%‐80% patients with persistent or recurrent Cushing's disease (CD), over a mean period 18‐24 months. Medical therapy is recommended as bridge while awaiting RT effect. Objective To determine long‐term outcome CRT and its predictors CD patients. Design, Setting Patients This retrospective case record analysis 42 who received treatment modality had at least 12 months post‐RT...
Abstract Objectives We report a case of pediatric thoracic tumor-induced osteomalacia (TIO) causing severe hypophosphatemic rickets with delayed diagnosis and emphasize on timely management this rare entity. Case presentation A young boy presented since five years age. Biochemical evaluation revealed hypophosphatemia, hyperphosphaturia, elevated alkaline phosphatase normal calcium levels. Initially managed as hereditary rickets, he was given phosphorus supplements calcitriol. Despite the...
Abstract Context Insulinoma needs accurate preoperative localization for minimally invasive surgery. Exendin‐4‐based imaging has shown promising results. Objective To evaluate performance parameters of exendin‐4‐based in insulinoma and compare with other modalities. Design Retrospective cross‐sectional study. Patients We report 14 patients endogenous hyperinsulinemic hypoglycaemia (EHH) managed at our centre; whom, the final diagnosis was (n = 11), Munchausen syndrome (MS) 2) inconclusive...