- Crystallization and Solubility Studies
- Dendrimers and Hyperbranched Polymers
- X-ray Diffraction in Crystallography
- Advanced Polymer Synthesis and Characterization
- Nanoparticle-Based Drug Delivery
- Crystallography and molecular interactions
- Thermal and Kinetic Analysis
- Synthesis and properties of polymers
- Nonlinear Optical Materials Research
- Organic Chemistry Cycloaddition Reactions
- Luminescence and Fluorescent Materials
- biodegradable polymer synthesis and properties
- Organic and Molecular Conductors Research
- RNA Interference and Gene Delivery
University of Mississippi
2015-2020
Bridge University
2015
This study represents a successful approach toward employing polycaprolactone-polyamidoamine (PCL-PAMAM) linear dendritic block copolymer (LDBC) nanoparticles as small-molecule carriers in NIR imaging and photothermal therapy. A feasible robust synthetic strategy was used to synthesize library of amphiphilic LDBCs with well-controlled hydrophobic-to-hydrophilic weight ratios. Systems hydrophobic ratio higher than 70% formed aqueous media, which show hydrodynamic diameters 51.6 96.4 nm. These...
Presented are design principles for the combinatory usage of HB, XB, and π–π interactions to enhance solid-state properties essential optoelectronic device application.
The use of a thiophene-based building block (<bold>Pyr-T</bold>) to achieve supramolecular assembly driven by halogen bonding (XB) is described. X-ray crystallography, NMR, Raman spectroscopy, and computational chemistry afford evidence strong XB π–π stacking.
ABSTRACT Herein, we present a facile and comprehensive synthetic methodology for the preparation of polyester‐polyamidoamine (PAMAM) (i.e., polyester: polylactide [PLA] (hydrophobic) polyamidoamine, PAMAM [hydrophilic]) polymers. A library PLA‐PAMAM linear dendritic block copolymers (LDBCs) in which both l d , were employed mass ratios 30:70, 50:50, 70:30, 90:10 (PLA:PAMAM) synthesized analyzed. When placed aqueous media, immiscibility hydrophilic hydrophobic segments leads to...
Abstract This study summarizes the synthesis, characterization, and evaluation of a library biocompatible self‐assembling Janus dendrimers (JDs) their resulting nanostructures possessing either cationic (NH 3 + ), anionic (COO − or neutral (OH) surface. Strategically designed for applications in therapeutic delivery, are comprised polyamidoamine (PAMAM) dendron as hydrophilic portion fatty acid (FA) functionalized dendrons hydrophobic portion. The physicochemical characterization vitro cell...