Some investigations have demonstrated that a combined endurance–strength training is the most effective in treatment of obesity. The aim research was to access how different trainings influence: endothelial function, lipid metabolism, and risk atherosclerosis women with In randomized trial, 39 obese aged 28–62 completed endurance (n = 22, 60-80% HRmax) or 17, 20 minutes strength exercises, 50–60% 1RM 25 training, HRmax). Before after intervention vascular function (endothelial nitric oxide...

The internet provides access to information about dietary supplements and allows their easy purchase. We aimed rank the interest of Google users in determine changes that occurred popularity from 2004 2019. used Trends generate data over time on regional (n = 200). categorized each included supplement calculated all topics proportion relative search volume (RSV) "lutein". analyzed trends categories. Globally, with highest were "magnesium", which was 23.72 times more popular than "lutein",...

Probiotics are known to regulate host metabolism. In randomized controlled trial we aimed assess whether interventions with probiotic containing following strains: Bifidobacterium bifidum W23, lactis W51, W52, Lactobacillus acidophilus W37, Levilactobacillus brevis W63, Lacticaseibacillus casei W56, Ligilactobacillus salivarius W24, Lactococcus W19, and W58 affect gut microbiota promote metabolic effects. By 16S rRNA sequencing analyzed the fecal of 56 obese, postmenopausal women into three...

Background and Objectives: Insulin resistance is a major contributor to the development of type 2 diabetes can be assessed using indirect indicators calculated from non-invasive tests. Asprosin recently discovered adipokine with postulated effect on glycemic regulation. This study aimed investigate correlation between serum asprosin levels insulin indices. The circulating obesity indices was also investigated. Materials Methods: A total 50 non-diabetic patients healthy volunteers were...

Dysregulated metabolism of homocysteine (Hcy) is associated with obesity. Supplementation probiotics can potentially be a natural therapeutic method for metabolic disorders. The precise mechanism in which microbiota affect Hcy obese individuals still unknown. aim this study was to evaluate the effects 12-week supplementation multispecies probiotic on levels, oxidative stress, inflammation and lipid profile patients. This randomized double-blind placebo-controlled trial performed 50 women...

Background: Recent studies indicate the important role of chronic inflammation and oxidative stress in pathogenesis hypertension. Green tea, due to high content catechins, shows antioxidant activity. Objective: To determine effect supplementation with green tea extract on blood pressure, concentration selected parameters status model high-sodium-diet induced Design: The study lasted 42 days. experimental population consisted 30 rats. rats were divided into three groups. control group fed a...

Many individuals search for obesity treatment options on the Internet. We aimed to analyze popularity of pharmacological and surgical methods searched by Google users.

A range of studies showed confusing data about the relationship between obesity, weight reduction and circulating total insulin-like growth factor -1 (IGF-1). The aim study was to compare influence orlistat (IO), metformin (IM), or calorie-restricted diet (LC) on IGF-1, with special respect insulin-resistance status. One hundred fourteen obese women aged from 18 40 years were divided into insulin sensitive (IS) resistant (IR) groups received a low calorie (LC), an isocaloric 500 mg twice...

Green tea extract exerts favorable influence on the lipid profile and insulin resistance in high-sodium intake arterial hypertension. A diet (HSD) was introduced to thirty Wistar rats create a model of Rats were randomized into three groups, 10 animals each. The SK group consumed HSD. SH2 HSD with 2 g green kg diet. SH4 fed 4 After six-week trial blood samples collected. serum concentrations glucose, lipids estimated, sensitivity calculated using homeostatic assessment (HOMA). Neither nor...

We aimed to characterize the parenteral supplementation services in Czechia, Ireland, Italy, Poland, and United Kingdom based on their websites. generated a list of websites by searching Google using term “vitamin infusion” selected cities with 250,000 citizens from each analyzed country. All search inputs were performed native language. Data features services, indications, contraindications, offered supplements, social media activity obtained. 317 representing 371 active facilities. Only 6...

This study aimed to evaluate the association of genetic variants in lactoferrin (LTF) metabolism-related genes with prevalence metabolically healthy obesity (MHO) and unhealthy (MUHO). In total, 161 MHO 291 MUHO subjects were recruited study. The following polymorphisms genotyped: low-density lipoprotein receptor-related protein (LRP) 2 rs2544390, LRP1 rs4759277, rs1799986, LTF rs1126477, rs2239692 rs1126478. We found significant differences genotype frequencies between subjects, CT variant...

Vitamin D fractions can be involved in the pathogenesis of metabolic disorders, but their concentrations are rarely determined. The aim this study was to evaluate concentration vitamin obese hypertensive patients and determine its associations with anthropometric parameters, glucose levels, lipid profiles. A total 85 (OBHT) 40 nonobese nonhypertensive subjects (NOBNHT) underwent biochemical measurements profiles, glycemia, 25-hydroxyvitamin (25(OH)D), free (free25(OH)D), binding protein,...

The influence of weight loss treatment on sex hormones profile has been studied mainly in women with polycystic ovary syndrome (PCOS), but obese premenopausal without PCOS it still remains unclear. aim the study was to evaluate effect two approaches obesity serum level child-bearing age PCOS.77 Caucasian (aged 31.2 ±8.3 years) were randomized into groups: 39 received a low-calorie diet (LC) and 38 an isocaloric plus metformin (IM), for 12 weeks. Anthropometric parameters, body composition...

Resistin is a proinflammatory adipokine involved in metabolic disorders. Its interplay with hypertriglyceridemia remains to be elucidated. We aimed evaluate the relationship between resistin (-420C/G) single nucleotide variant (SNV) and parameters preference for fried food consumption hypertriglyceridemia.The study enrolled 179 hypertriglyceridemic (HTG) 182 normotriglyceridemic (NTG) patients. Anthropometric measurements, serum resistin, insulin fasting glucose concentration, homeostatic...

Detection of the seasonal patterns healthy and unhealthy behavior could be helpful for designing individual population health interventions programs. This study investigates variation in sales common types products Poland Polish Google queries related to behavior.

Background: Insulin resistance, a key factor in developing type 2 diabetes mellitus, is linked to various health conditions. The basis of its treatment lifestyle modification. However, adherence nutritional and other medical recommendations can be challenging for chronic disease patients due many factors, including demographics, social context, gender, age, the patient’s baseline condition. This study aims evaluate impact online support group members on diet quality women with insulin...