A5109982573- Advanced X-ray and CT Imaging
- Cardiac Imaging and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Radiation Dose and Imaging
- Paraoxonase enzyme and polymorphisms
- Cancer Risks and Factors
- Cardiac Health and Mental Health
- Neuroinflammation and Neurodegeneration Mechanisms
- Gene expression and cancer classification
- Cardiovascular Disease and Adiposity
- Health Promotion and Cardiovascular Prevention
- Liver Disease Diagnosis and Treatment
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Coronary Artery Anomalies
- Atherosclerosis and Cardiovascular Diseases
Mayo Clinic
2000
Understanding the genetic basis of gene expression can shed light on regulatory mechanisms underlying complex traits and diseases. Single-cell resolved measures RNA levels single-cell quantitative trait loci (sc-eQTLs) have revealed regulation that drives sub-tissue cell states types across diverse human tissues. Here, we describe first phase TenK10K, largest-to-date dataset matched whole-genome sequencing (WGS) RNA-sequencing (scRNA-seq). We leverage scRNA-seq data from over 5 million cells...
Myeloperoxidase (MPO) plays a critical role in the innate immune response and has been suggested to be surrogate marker of oxidative stress inflammation, with elevated levels implicated cardiovascular diseases, such as atherosclerosis heart failure, well conditions like rheumatoid arthritis cancer. While MPO is well-known leukocytes, its expression function human endothelial cells remain unclear. This study investigates patient-derived colony-forming (ECFCs) potential association CAD...