A5019356756- Material Dynamics and Properties
- Mechanical and Optical Resonators
- Advanced MEMS and NEMS Technologies
- Acoustic Wave Resonator Technologies
- Theoretical and Computational Physics
- Advanced Thermodynamics and Statistical Mechanics
- Evolution and Genetic Dynamics
- Protein Structure and Dynamics
- Mathematical and Theoretical Epidemiology and Ecology Models
- Influenza Virus Research Studies
- Geological formations and processes
- Plant and animal studies
- Domain Adaptation and Few-Shot Learning
- Recommender Systems and Techniques
- Nonlinear Dynamics and Pattern Formation
- Phase-change materials and chalcogenides
- Cellular Mechanics and Interactions
- Hydrology and Sediment Transport Processes
- Natural Language Processing Techniques
- Neuroscience and Neural Engineering
- Chaos control and synchronization
- Hemoglobin structure and function
- thermodynamics and calorimetric analyses
- Explainable Artificial Intelligence (XAI)
- Mobile Crowdsensing and Crowdsourcing
Google (United States)
2021-2025
Hunan Normal University
2023
Chan Zuckerberg Initiative (United States)
2020
University of California, Santa Barbara
2016-2019
Instituto de Física Teórica
2018
University of California System
2017
Santa Barbara City College
2017
New York University
2013-2016
Guangzhou University
2012-2014
Tianjin University of Science and Technology
2010
A-Maize-ing Maize is one of our oldest and most important crops, having been domesticated approximately 9000 years ago in central Mexico. Schnable et al. (p. 1112 ; see the cover) present results sequencing B73 inbred maize line. The findings elucidate how became diploid after an ancestral doubling its chromosomes reveals transposable element movement activity recombination. Vielle-Calzada 1078 ) have sequenced Palomero Toluqueño ( landrace, a highland popcorn from Mexico, which, when...
Significance In allosteric proteins, binding a ligand affects activity at distant site. The physical principles allowing for such an action distance are not well understood. Here we introduce numerical scheme to evolve materials in which the number of solutions, their spatial architectures, and correlations among them can be computed. We show that allostery these uses recently discovered elastic edge modes near active site transmit information, generated during evolution alone reveal key...
Biomass-derived 2,5-bis(hydroxymethyl)furan (BHMF) has received great attention and interest due to its broad application prospects in polyesters medicine. Over the past decades, catalytic systems including thermocatalytic, biocatalytic, electrocatalytic, photocatalytic hydrogenation of 5-hydroxymethylfurfural (HMF) into BHMF have been developed a extent. To understand present status challenges production, this review systematically evaluates recent findings developments HMF through various...
Rapidly evolving pathogens like influenza viruses can persist by changing their antigenic properties fast enough to evade the adaptive immunity, yet they rarely split into diverging lineages. By mapping multi-strain Susceptible-Infected-Recovered model onto traveling wave of adapting populations, we demonstrate that persistence a rapidly evolving, Red-Queen-like state pathogen population requires long-ranged cross-immunity and sufficiently large sizes. This is unstable goes extinct or...
Amorphous solids tend to present an abundance of soft elastic modes, which diminish their transport properties, generate heterogeneities in response, and affect non-linear processes like thermal activation plasticity.This is especially true packings particles near jamming transition, for effective medium theory variational arguments can both predict the density vibrational modes.However, recent numerics support that one hypothesis argument does not hold.We provide a novel overcomes this...
Models for confluent biological tissues often describe the network formed by cells as a triple-junction network, similar to foams. However, higher-order vertices or multicellular rosettes are prevalent in developmental and vitro processes have been recognized crucial many important aspects of morphogenesis, disease, physiology. In this work, we study influence on mechanics tissue. We find that existence tissue can greatly its rigidity. Using generalized vertex model effective medium theory,...
Supercooled liquids are characterized by their fragility: The slowing down of the dynamics under cooling is more sudden and jump specific heat at glass transition generally larger in fragile than strong ones. Despite importance this quantity classifying liquids, explaining what aspects microscopic structure controls fragility remains a challenge. Surprisingly, experiments indicate that linear elasticity glass—a purely local property free energy landscape—is good predictor fragility. In...
Existing work on search result diversification typically falls into the "next document" paradigm, that is, selecting next document based ones already chosen. A sequential process of documents one-by-one is naturally modeled in learning-based approaches. However, such a makes learning difficult because there are an exponential number ranking lists to consider. Sampling usually used reduce computational complexity but this less effective. In paper, we propose soft version paradigm which...
This letter introduces a resonant mass sensor that is based on lateral extensional mode piezoelectric resonator and has minimum detectable of 10−15g at room temperature atmospheric pressure. The with size about 200×50×1μm3 quality factor (Q) >1400 60MHz, as small 0.1ppm shift its frequency can be detected. detection capability corresponds to uncertainty only 4.6fg. We have experimentally demonstrated ∼1.6ppm due absorption isopropanol vapor (73fg) the sidewalls parylene-coated resonator.
We study the evolution of structural disorder under cooling in supercooled liquids, focusing on covalent networks. introduce a model for energy networks that incorporates weak noncovalent interactions. show at low temperature these interactions considerably affect network topology near rigidity transition occurs as coordination increases. As result, this becomes mean field and does not present line critical points previously argued for, ``rigidity window.'' Vibrational modes are then...
Marginal stability is the notion that achieved, but only barely so. This property constrains ensemble of configurations explored at low temperature in a variety systems, including spin, electron, and structural glasses. A key feature marginal states (saturated) pseudogap distribution soft excitations. We examine how such pseudogaps appear dynamically by studying Sherrington-Kirkpatrick (SK) spin glass. After revisiting correcting multi-spin-flip criterion for local stability, we show...
The dynamical properties and mechanical functions of amorphous materials are governed by their microscopic structures, particularly the elasticity interaction networks, which is generally complicated structural heterogeneity. This ubiquitous heterogeneous nature intriguingly attributed to a complex role entropy. Here, we show in disordered networks that vibrational entropy increases creating phase-separated structures when connectivity close onset network rigidity. stress-energy, conversely...
Two-tower architecture is commonly used in real-world systems for Unbiased Learning to Rank (ULTR), where a Deep Neural Network (DNN) tower models unbiased relevance predictions, while another observation biases inherent the training data like user clicks. This two-tower introduces inductive allow more efficient use of limited observational logs and better generalization during deployment than single-tower that may learn spurious correlations between predictions biases. However, despite...
Learning-to-Rank (LTR) systems are ubiquitous in web applications nowadays. The existing literature mainly focuses on improving ranking performance by trying to generate the optimal order of candidate items. However, virtually all advanced functions not scale calibrated. For example, rankers have freedom add a constant item scores without changing their relative order. This property has resulted several limitations deploying methods practice. On one hand, it limits use effective important...
Glassy systems are disordered characterized by extremely slow dynamics. Examples supercooled liquids, whose dynamics down under cooling. The specific pattern of slowing-down depends on the material considered. This dependence is poorly understood, in particular, it remains generally unclear which aspects microscopic structures control and other macroscopic properties. Attacking this question one two main dissertation. We have introduced a new class models captures central correspondence...
Significance The response of erodible granular beds to shearing flows controls numerous natural phenomena. A central aspect is the existence a threshold stress below which erosion stops, and whose microscopic underpinning debated. We use an experiment where this spontaneously reached study spatial organization flux. find that heterogeneous in space occurs along favored channels distribution extremely broad, with strongly anisotropic correlations. These findings can be quantitatively...
Unbiased learning to rank (ULTR) studies the problem of mitigating various biases from implicit user feedback data such as clicks, and has been receiving considerable attention recently. A popular ULTR approach for real-world applications uses a two-tower architecture, where click modeling is factorized into relevance tower with regular input features, bias bias-relevant inputs position document. successful factorization will allow be exempt biases. In this work, we identify critical issue...
A lectin from Musca domestica larva was purified by affinity chromatography on a glactose-Sepharose 4B column. (MLL) inhibited the growth of BEL-7402 cells in time and concentration-dependent way. The results Hoechst 33258 staining indicated that MLL induce apoptosis based typical apoptotic morphological changes. Subsequently, we found treatment abrogated glutathione antioxidant system induced mitochondria to generate reactive oxygen species (ROS) accumulation, resulting reduction...
We introduce a numerical scheme to evolve functional materials that can accomplish specified mechanical task. In this scheme, the number of solutions, their spatial architectures and correlations among them be computed. As an example, we consider “allosteric” task, which requires material respond specifically stimulus at distant active site. find functioning less-constrained trumpet-shaped region connecting sites, amplitude elastic response varies non-monotonically along trumpet. previously...