- Vasculitis and related conditions
- Neurological Complications and Syndromes
- Ophthalmology and Eye Disorders
- Cerebrovascular and Carotid Artery Diseases
- Moyamoya disease diagnosis and treatment
- Muscle Physiology and Disorders
- HIV-related health complications and treatments
- HIV Research and Treatment
- Systemic Lupus Erythematosus Research
- Intracranial Aneurysms: Treatment and Complications
- Neurological and metabolic disorders
- MRI in cancer diagnosis
- Infectious Encephalopathies and Encephalitis
- Genetic Neurodegenerative Diseases
- Pharmacological Effects and Toxicity Studies
- Cytomegalovirus and herpesvirus research
- Glioma Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Hereditary Neurological Disorders
- Williams Syndrome Research
- Lysosomal Storage Disorders Research
- Otitis Media and Relapsing Polychondritis
- Radiomics and Machine Learning in Medical Imaging
- Spatial Neglect and Hemispheric Dysfunction
- Renal and Vascular Pathologies
Vita-Salute San Raffaele University
2014-2024
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2015-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2024
Azienda Ospedaliera Sant’Antonio Abate di Gallarate
2024
San Raffaele University of Rome
2010-2018
University College London
2018
IRCCS Ospedale San Raffaele
2018
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2015
University of Milan
2015
Heliophysics
2010
At a European Society of Neuroradiology (ESNR) Annual Meeting 2015 workshop, commonalities in practice, current controversies and technical hurdles glioma MRI were discussed. We aimed to formulate guidance on determine its feasibility, by seeking information imaging practices from the community. Invitations structured survey emailed ESNR members (n=1,662) associates (n=6,400), national radiologists’ societies distributed via social media. Responses received 220 institutions (59% academic)....
Research Article5 November 2015Open Access Source Data Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy Giulio Cossu Corresponding Author Institute Inflammation and Repair, University Manchester, UK Search for more papers by this author Stefano C Previtali Experimental Neurology (InSpe), Division Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy Department Neurology, Sara Napolitano HSR/TIGET Pediatric Clinical Unit,...
To describe the magnetic resonance (MR) imaging and diffusion-weighted (DW) features of ocular adnexal lymphomas (OALs), to determine diagnostic accuracy apparent diffusion coefficient (ADC) for discriminating OALs from other orbital mass lesions, assess whether variations in ADC constitute a reliable biomarker OAL response therapy.Institutional ethical committee approval informed consent were obtained. In this prospective study, 114 white subjects (65 females 49 males) enrolled....
Abstract Objective The aim of this study was to evaluate the usefulness magnetic resonance imaging ( MRI ) in detecting progression Duchenne muscular dystrophy DMD by quantification fat infiltration FI and muscle volume index MVI , a residual‐to‐total ratio). Methods Twenty‐six patients (baseline age: 5–12 years) with genetically proven were longitudinally analyzed lower limb 3T force measurements, functional tests (Gowers, 10‐m time, North Star Ambulatory Assessment, 6‐min walking test)....
Abstract Arterial involvement is the cardinal feature of large-vessel vasculitis (LVV) and prevention disease progression principal therapeutic goal. However, development tools for its evaluation represents a major unmet need. To address this, widely-applicable imaging tool LVV, analysing arterial in 17 territories, has been developed validated. Individual stenosis dilation scores were generated combined composite score. The methodology was validated cross-sectionally longitudinally 131...
Background. To determine whether treatment with ritonavir-boosted protease inhibitor (PI) monotherapy is associated detrimental effects on neurocognitive function or brain imaging markers compared to standard antiretroviral therapy (ART). Methods. Neuropsychological assessment and magnetic resonance were performed at the last study visit in a subset of participants randomized PI (PI-mono group) ongoing triple ART (OT PIVOT trial. We calculated global z-score (NPZ-7) from average individual...
Chromogranin-A (CgA) is a secretory protein processed into peptides that regulate angiogenesis and vascular cells activation, migration proliferation. These processes may influence arterial inflammation remodelling in Takayasu arteritis (TA). Plasma levels of full-length CgA (CgA439), fragments lacking the C-terminal region (CgA-FRs) N-terminal fragment, CgA1–76 (vasostatin-1, VS-1) were analysed 42 patients with TA 20 healthy age-matched controls. Vascular was longitudinally assessed by...
Purpose: Spinocerebellar ataxias type 2 and 28 (SCA2, SCA28) are autosomal dominant disorders characterized by progressive cerebellar oculomotor abnormalities. We aimed to investigate cerebellar, brainstem, extraocular muscle involvement in the mitochondrial SCA28 disease compared with SCA2. Methods: obtained orbital brain 1.5 T–magnetic resonance images (MRI) eight subjects, nine SCA2, age-matched healthy subjects. Automated segmentation of cerebellum frontal lobe was performed using...
To describe high-resolution brain vessel wall MRI (VW-MRI) patterns and morphological findings in central nervous system (CNS) vasculitis patients.
Visuo-motor adaptation to optical prisms (
Protease inhibitor monotherapy (PIM) for human immunodeficiency virus (HIV) may exert suboptimal viral control in the central nervous system. We determined whether cerebral blood flow (CBF) and regional brain volumes were associated with PIM, specific cognitive domains imaging biomarkers.Cognitive assessments magnetic resonance performed after final visit of a randomized HIV-treatment strategy trial. Participants virologically suppressed on triple therapy at trial entry followed 3-5 years....
We report an uncommon, infratentorial localization of adult H3 K27M-altered diffuse midline glioma arising in a particularly rare site (medulla oblongata). In addition to this unusual presentation, the lesion exhibited substantial contrast enhancement and size decrease after dexamethasone, generating diagnostic dilemmas. Histology, molecular details, advanced Magnetic Resonance imaging features differential diagnoses are here described discussed, as well common misconceptions about...