A5058583715- Neural dynamics and brain function
- Migration, Health and Trauma
- Posttraumatic Stress Disorder Research
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Child Abuse and Trauma
- Neural and Behavioral Psychology Studies
- Resilience and Mental Health
- Neuroscience and Music Perception
- Stress Responses and Cortisol
- Child and Adolescent Psychosocial and Emotional Development
- Health and Conflict Studies
- Memory and Neural Mechanisms
- Heart Rate Variability and Autonomic Control
- Psychiatric care and mental health services
- Hearing Loss and Rehabilitation
- Transcranial Magnetic Stimulation Studies
- Neurobiology of Language and Bilingualism
- Hearing, Cochlea, Tinnitus, Genetics
- Muscle activation and electromyography studies
- Motor Control and Adaptation
- Neural Networks and Applications
- Identity, Memory, and Therapy
- Bullying, Victimization, and Aggression
- Psychosomatic Disorders and Their Treatments
University of Konstanz
2016-2025
Light University of Bujumbur
2014-2024
LMU Klinikum
2024
Ludwig-Maximilians-Universität München
2024
PE International (Germany)
2009-2023
International Solar Energy Research Center Konstanz
2010-2022
Hudson Institute
2020
Mbarara University of Science and Technology
2015-2017
University of Tübingen
1985-2015
Allensbach Institute
2009-2012
Magnetic source imaging revealed that the cortical representation of digits left hand string players was larger than in controls. The effect smallest for thumb, and no such differences were observed representations right digits. amount reorganization fingering correlated with age at which person had begun to play. These results suggest different parts body primary somatosensory cortex humans depends on use changes conform current needs experiences individual.
Magnetic source imaging was used to determine whether tonotopy in auditory cortex of individuals with tinnitus diverges from normative functional organization. Ten subjects and 15 healthy controls were exposed four sets tones while magnetoencephalographic recordings obtained the two cortical hemispheres sequence. A marked shift representation frequency into an area adjacent expected tonotopic location observed. The Euclidean distance trajectory map 5.3 mm (SD = 3.1) compared a 2.5 1.3)...
Abstract —Patients with chronic aphasia were assigned randomly to a group receive either conventional therapy or constraint-induced (CI) therapy, new therapeutic technique requiring intense practice over relatively short period of consecutive days. CI is realized in communicative environment constraining patients systematically speech acts which they have difficulty. Patients both groups received the same amount treatment (30 35 hours) as 10 days massed-practice language exercises for (3...
Hemodynamic and electrophysiological studies indicate differential brain response to emotionally arousing, compared neutral, pictures. The time course source distribution of electrocortical potentials in emotional stimuli, using a high‐density electrode (129‐sensor) array were examined here. Event‐related (ERPs) recorded while participants viewed pleasant, unpleasant ERP voltages six intervals, roughly corresponding P1, N1, early P3, late P3 slow wave window. Differential activity was found...
Little is known about the usefulness of psychotherapeutic approaches for traumatized refugees who continue to live in dangerous conditions. Narrative exposure therapy (NET) a short-term approach based on cognitive-behavioral and testimony therapy. The efficacy narrative was evaluated randomized controlled trial. Sudanese living Ugandan refugee settlement (N = 43) were diagnosed as suffering from posttraumatic stress disorder (PTSD) either received 4 sessions NET, supportive counseling (SC),...
The visual brain quickly sorted stimuli for emotional impact despite high-speed presentation (3 or 5 per s) in a sustained, serial torrent of 700 complex pictures. Event-related potentials, recorded with dense electrode array, showed selective discrimination emotionally arousing from less affective content. Primary sources this activation were over the occipital cortices, extending to right parietal cortex, suggesting processing focus posterior system. Emotion was independent formal...
With the advent of dense sensor arrays (64-256 channels) in electroencephalography and magnetoencephalography studies, probability increases that some recording channels are contaminated by artifact. If all required to be artifact free, number acceptable trials may unacceptably low. Precise screening is necessary for accurate spatial mapping, current density measures, source analysis, temporal analysis based on single-trial methods. presents a problems given large datasets. We propose...
Prenatal exposure to maternal stress can have lifelong implications for psychological function, such as behavioral problems and even the development of mental illness. Previous research suggests that this is due transgenerational epigenetic programming genes operating in hypothalamic-pituitary-adrenal axis, glucocorticoid receptor (GR). However, it not known whether intrauterine affects state these beyond infancy. Here, we analyze methylation status GR gene mothers their children, at 10-19...
Abstract Background Political instability and the civil war in Southern Sudan have resulted numerous atrocities, mass violence, forced migration for vast parts of civilian population West Nile region. High exposure to traumatic experiences has been particularly prominent Ugandan Sudanese Region, representing an indication psychological strain posed by years armed conflict. Methods In this study impact events on prevalence severity posttraumatic stress disorder (PTSD) a random sample 3.339...
Focal hand dystonia involves a loss of motor control one or more digits; it is associated with the repetitive, synchronous movements digits made by musicians over periods many years. Magnetic source imaging revealed that there smaller distance (fusion) between representations in somatosensory cortex for affected dystonic than hands non-musician subjects. The data suggest use-dependent susceptibility to digital representation fusion may be involved etiology focal dystonia. A successful...
Background The neurophysiological mechanisms underlying tinnitus perception are not well understood. Surprisingly, there have been no group studies comparing abnormalities in ongoing, spontaneous neuronal activity individuals with and without perception. Methods Findings Here, we show that the of a (n = 17) is characterised by marked reduction alpha (8–12 Hz) power together an enhancement delta (1.5–4 as compared to normal hearing control 16). This pattern was especially pronounced for...
MAGNETIC source imaging revealed that the topographic representation in somatosensory cortex of face area upper extremity amputees was shifted an average 1.5 cm toward would normally receive input from now absent nerves supplying hand and fingers. Observed alterations provide evidence for extensive plastic reorganization adult human following nervous system injury, but they are not a sufficient cause phantom phenomenon termed 'facial remapping'.
Tinnitus is defined by an auditory perception in the absence of external source sound. This condition provides distinctive possibility extracting neural coding perceptual representation. Previously, we had established that tinnitus characterized enhanced magnetic slow-wave activity (∼4 Hz) perisylvian or putatively regions. Because works linking high-frequency oscillations to conscious sensory and positive symptoms a variety disorders, examined gamma band during brief periods marked...
We postulate that the cascade “Freeze-Flight-Fight-Fright-Flag-Faint” is a coherent sequence of six fear responses escalate as function defense possibilities and proximity to danger during life-threat. The actual trauma-related response dispositions acted out in an extremely dangerous situation therefore depends on appraisal threat by organism relation her/his own power act (e.g., age gender) well perceived characteristics perpetrator. These reaction patterns provide optimal adaption for...
Traumatic stress due to conflict and war causes major mental health problems in many resource-poor countries.The objective of this study was examine whether trained lay counselors can carry out effective treatment posttraumatic disorder (PTSD) a refugee settlement.In randomized controlled dissemination trial Uganda with 277 Rwandan Somalian refugees who were diagnosed PTSD the authors investigated effectiveness psychotherapy administered by counselors.Strictly manualized narrative exposure...
The psychological rehabilitation of former child soldiers and their successful reintegration into postconflict society present challenges. Despite high rates impairment, there have been no randomized controlled trials examining the feasibility efficacy mental health interventions for soldiers.To assess a community-based intervention targeting symptoms posttraumatic stress disorder (PTSD) in formerly abducted individuals.Randomized trial recruiting 85 with PTSD from population-based survey...
The North-Eastern part of Sri Lanka had already been affected by civil war when the 2004 Tsunami wave hit region, leading to high rates posttraumatic stress disorder (PTSD) in children. In acute aftermath we tested efficacy two pragmatic short-term interventions applied trained local counselors.A randomized treatment comparison was implemented a refugee camp severely community. 31 children who presented with preliminary diagnosis PTSD were randomly assigned either six sessions Narrative...
Over the past three decades, research and clinical practice related to field of traumatic stress have developed tremendously. In parallel with steady accumulation basic knowledge, therapeutic approaches been treat people suffering from posttraumatic disorder (PTSD) other trauma-related psychological problems. Today, a number evidence-based treatments are available. They differ in various ways; however, they also commonalities. Given this situation, clinicians may wonder which treatment...