Guangwen Zhu

ORCID: 0000-0003-1338-0367
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About
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Research Areas
  • Polyomavirus and related diseases
  • Head and Neck Surgical Oncology
  • Salivary Gland Disorders and Functions
  • Cancer Diagnosis and Treatment
  • Acute Kidney Injury Research
  • Bone health and osteoporosis research
  • Sinusitis and nasal conditions
  • Salivary Gland Tumors Diagnosis and Treatment
  • Systemic Sclerosis and Related Diseases
  • Systemic Lupus Erythematosus Research
  • Sirtuins and Resveratrol in Medicine
  • Multicomponent Synthesis of Heterocycles
  • Ocular Oncology and Treatments
  • Gestational Diabetes Research and Management
  • Medical Imaging and Pathology Studies
  • Organ Donation and Transplantation
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Zoonotic diseases and public health
  • Full-Duplex Wireless Communications
  • Antioxidant Activity and Oxidative Stress
  • Obesity, Physical Activity, Diet
  • Gas Sensing Nanomaterials and Sensors
  • Oral and Maxillofacial Pathology
  • Toxoplasma gondii Research Studies
  • Thyroid Cancer Diagnosis and Treatment

First People’s Hospital of Zunyi
2023-2024

Jiangsu Institute of Parasitic Diseases
2023-2024

First Affiliated Hospital of Dalian Medical University
2006-2023

Dalian Medical University
2006-2023

Austin Hospital
2016

Nanjing Medical University
2011

Nanjing Maternity and Child Health Care Hospital
2011

Shanghai Medical College of Fudan University
1993-2010

Fudan University Shanghai Cancer Center
2003-2010

Henry Ford Hospital
2003

Anaplastic thyroid cancer (ATC) is a highly lethal undifferentiated malignancy without reliable therapies. Retinoic acid (RA) has been employed to promote redifferentiation of cancers by increasing their I131 uptake and radio-sensitivity, but its effect(s) on ATCs not yet ascertained. Likewise, resveratrol induces but, also in this case, effects remain unknown. These issues have addresses the current study using three human ATC cell lines (THJ-11T, THJ-16T, THJ-21T) through multiple...

10.3390/ijms19041030 article EN International Journal of Molecular Sciences 2018-03-29

Based on the self-assembly of conjugated polymers (CPs) with paclitaxel constructed as nanoparticles (NPs) exhibiting luminescence properties through AILE mechanism, a novel type pH-responsive nanoparticle was developed, featuring color change that indicated drug molecule release. The characterized by their were straightforward to prepare, exhibited exceptional stability, and demonstrated high loading capacity sensitive release profile under acidic conditions. These NPs could drugs within...

10.1039/d5nr00540j article EN Nanoscale 2025-01-01

Background Reducing the incidence rate of persistent/recurrent HPT after surgery is key to treatment PHPT. The pitfalls preoperative, intraoperative, and postoperative management in PHPT patients their potential impact on surgical strategies need be comprehensively investigated. Methods demographic, biochemical, radiological results other clinical data enrolled 112 with primary hyperparathyroidism undergoing were obtained from our database this retrospective cohort study. One-way analysis...

10.3389/fonc.2025.1535089 article EN cc-by Frontiers in Oncology 2025-05-15

Based on the principle of intermolecular interactions aggregation-induced locally excited emission (AILE) luminescence mechanism, two-stage functional conjugated polymers (CPs) capable scavenging ethanolamine (ETA) and nanoprobes with detecting formaldehyde (FA) were designed developed. The PFOP-NEt3(+)-based nanomaterial is simple to synthesize, easy use, versatile, atom-economical, photostability, biocompatible. In first stage, can process stabilize water pollutant ethanolamine. second...

10.1021/acsapm.4c02367 article EN ACS Applied Polymer Materials 2024-11-04

Abstract Background The exact diagnosis of double primary papillary adenocarcinoma thyroid and lung is even rarer, to our knowledge no report in the literature by [ 18 F]-2-fluoro-2-deoxy-D-glucose-positron emission tomography/X-ray CT(FDG PET/CT) with surgical specimens immunohistochemistry(IHC). We a patient abnormal FDG PET/CT lung, this unusual presentation may lead misdiagnosis without IHC. Case A 56-year-old man coughing three months. was performed, resection were detected hematoxylin...

10.1186/1477-7819-9-119 article EN cc-by World Journal of Surgical Oncology 2011-10-06

Knowledge of critical care nurses' intravenous fluid bolus therapy (FBT) practice remains underexplored. Using a multi-choice online survey conducted between September and October 2014, we sought to describe the self-reported nurses located in Australia New Zealand. Two hundred ninety-five responded with most practising adult ICUs. Overall, 0.9% saline solution was preferred for FBT. However, more Australian than Zealand respondents ‘albumin 4%’ (31% versus 3.6%, P <0.01) In contrast,...

10.1177/0310057x1604400108 article EN Anaesthesia and Intensive Care 2016-01-01

Abstract Objectives To update Schall's classification for Sjögren's syndrome (SS) by the new quantitative stimulation test with dynamic salivary glands scintigraphy (qsDSGS) and to standardize gland scintigraphy. Methods The histopathology, oral, ocular, serological examination qsDSGS of 268 consecutive patients suggestive SS were evaluated in this retrospective cohort study. included 15 autoantibodies, antinuclear antibodies (ANA) so on. diagnostic thresholds functional parameters set...

10.1111/1756-185x.13779 article EN International Journal of Rheumatic Diseases 2019-12-21

To create risk predictive models of healthcare-seeking delay among imported malaria patients in Jiangsu Province based on machine learning algorithms, so as to provide insights into early identification cases Province.Case investigation, first symptoms and time initial diagnosis 2019 were captured from Infectious Disease Report Information Management System Parasitic Prevention Control Chinese Center for Prevention. The created with the back propagation (BP) neural network model, logistic...

10.16250/j.32.1374.2022290 article EN PubMed 2023-06-28

The cerebellum is less affected by normal aging or neurodegenerative diseases, the aim of this paper to investigate effect renal function status on uptake 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG) in human based independent creatinine (CRE) blood urea nitrogen (BUN) levels.A total 253 patients who underwent 18F-FDG PET/CT scans were included. divided into groups according status: 201 with function, 16 increase CRE, 36 decrease and 31 abnormal BUN. maximum standardized values obtained regions...

10.21037/qims-22-917 article EN Quantitative Imaging in Medicine and Surgery 2023-07-20

Merkel cell carcinoma (MCC) is a rare primary neuroendocrine commonly found in older adults areas of the skin that are susceptible to ultraviolet ray damage. The current study reports case 79‑year‑old woman who presented Affiliated Hospital Zunyi Medical University (Zunyi, China) with painless lump lower eyelid left eye accompanied by photophobic tears for 4 months. Head computed tomography (CT) and magnetic resonance imaging (MRI) showed space‑occupying lesion ~2.8x2.4 cm size outside...

10.3892/ol.2024.14252 article EN Oncology Letters 2024-01-23

To investigate the development and dynamic changes of cysts in brain mice following infection with different forms

10.16250/j.32.1374.2024044 article EN PubMed 2024-06-07

10.1016/s0360-3016(03)01290-2 article EN International Journal of Radiation Oncology*Biology*Physics 2003-09-12

Nesidioblastosis is a rare cause of hyperinsulinemic hypoglycemia in adults and its clinical features are similar to those insulinoma with recurrent hypoglycemic attacks. The present study reports the case 48-year-old man who visited Affiliated Hospital Zunyi Medical University (Zunyi, China) 5-year history symptoms such as dizziness palpitations. Abdominal magnetic resonance imaging (MRI) showed mass ~1.2x1.0 cm head pancreas, which was suspected be an insulinoma. For confirmation, patient...

10.3892/etm.2023.12330 article EN Experimental and Therapeutic Medicine 2023-11-28
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