A5106406511- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Axial and Atropisomeric Chirality Synthesis
- Catalytic Alkyne Reactions
- Asymmetric Synthesis and Catalysis
- Multicomponent Synthesis of Heterocycles
- Chemical Synthesis and Reactions
- Phenothiazines and Benzothiazines Synthesis and Activities
- Asymmetric Hydrogenation and Catalysis
University of Turin
2021-2024
Chemi (Italy)
2024
Torino e-district
2021
A chiral heterogeneous catalyst derivative of (-)-4,5-dimethyl-3,6-bis(1-naphthyl)-1,2-benzenedisulfonimide is proven here to be efficient in a three-component asymmetric Passerini protocol, carried out deep eutectic solvent. Reaction conditions are mild and green, while enantioselectivity excellent. The was easily recovered reused with no decrease its catalytic activity.
Abstract We herein report that the highly hydrophobic ether 4‐MeTHP constitutes a promising resource for development of sustainable synthetic methodologies grounded on use organometallic reagents. The beneficial effects as reaction medium are illustrated in organolithium‐promoted anionic ortho ‐Fries rearrangement 1,1’‐bi‐2‐naphthol (BINOL)‐based carbamates under bench‐type conditions. induces remarkable and unexpected stability organolithiums species, enabling efficient preparation chiral...
The reactivity of "furan-ynes" in combination with pyridine and quinoline N-oxides the presence a Au(I) catalyst, has been studied, enabling synthesis three different heterocyclic scaffolds. Selective access to two out possible products, dihydropyridinone furan enone, achieved through fine-tuning reaction conditions. reactions proceed smoothly at room temperature open-air, were further extended broad substrate scope, thus affording functionalized dihydropyridinones pyranones.