The purpose of the study is to find out overall incidence superscan among different type cancers, causes and its relationship with other parameters such as age, sex, duration disease, serum alkaline phosphatase (ALP) levels. This was a retro-prospective study. Records all previous bone scans reported patients were re-evaluated retrospectively. Patients who diagnosed having in preceding 3 years confirmed histopathological diagnosis included retrospective group. In prospective group, have...

BACKGROUND: Among various polymorphic variants of TP53 gene, codon 72 polymorphism (Arg72Pro) has been found to be associated with cancer susceptibility, but only few studies have investigated their effect on thyroid risk. OBJECTIVE: A case control study was conducted elucidate the possi ble role this SNP as risk factor in development and examine its correlation clinicopathological variables. METHODS: In study, we tested genotype distribution by PCR-RFLP 140 patients 200 cancer-free controls...

Abstract Radionuclide whole-body bone scan is a useful investigation of choice to detect the skeletal metastases in prostate cancer. It indicated patients having elevated serum prostate-specific antigen (Sr. PSA) or with pain. Elevated Sr. PSA levels have high predictive value for metastases; however, there no consensus regarding cut-off above which indicated. This study was performed find out accuracy test and know optimal sensitivity specificity prediction on cancer patients. A...

ABSTRACT Rearranged during Transfection ( RET ) gene polymorphisms act to influence thyroid cancer in a polygenic and low‐penetrance manner no study regarding alterations has undergone from this part of the world (North India). We evaluated G691S rs 1799939), L769L 1800861), S904S 1800863) elucidate their possible role as risk factors papillary (PTC) follicular (FTC). Polymorphic analysis was performed by polymerase chain reaction (PCR), followed restriction fragment length polymorphism...

AbstractPlant-isolated compounds, Osthol [7-methoxy-8-(3-methylbut-2-enyl) coumarin], were subjected to modification in the isopentenyl side chain get an aldehyde of 2-methyl-4 (7-methoxy-2-oxo-2H-chromen-8-yl)-but-2-en-1-al. This modified compound was exposed γ-radiation produced by 137Cs source at room temperature. Pre- and post-irradiation study carried out ultraviolet–visible spectroscopy. The shows a sharp absorption peak 322 nm. observed band decreases with irradiation up certain dose...

Objectives The differentiation between the various etiologies of thyrotoxicosis, including those with hyperthyroidism (especially Graves' disease [GD], most common cause hyperthyroidism) and without (like thyroiditis), is an important step in planning specific therapy. Technetium-99m (99mTc) pertechnetate thyroid scanning gold standard differentiating GD from thyroiditis. However, this technique has limited availability, contraindicated pregnancy lactation, not helpful cases history recent...

Objectives Neonatal cholestasis is a common cause of jaundice among newborns. Hepatobiliary scintigraphy plays an important role in the diagnosis neonatal by ruling out extrahepatic biliary atresia, which one causes. Phenobarbitone and ursodeoxycholic acid (UDCA) have been used to improve specificity hepatobiliary obstructive causes syndrome (NCS). The present study was undertaken compare utility phenobarbitone UDCA augmenting evaluation NCS. Materials methods Seventy-four consecutive...

Dyshormonogenetic goiter refers to familial goiters owing an inherited defect in the metabolism of thyroid hormones.19 patients with clinical and biochemically proven hypothyroidism (low T3, FT4 high TSH) were recruited for study. All subjected (i) ultrasound neck rule out dysgenesis (ii) technetium-99m radionuclide scintigraphy a perchlorate discharge test (PDT). Extrathyroidal malformations identified by (USG) examination abdomen pelvis echocardiography.Out 19 elevated uptakes on...

In the present paper, Osthol (molecular formula: C15H16O3; molecular mass: 244) was obtained from plant Prangos pabularia by column chromatography technique. This compound simultaneously exposed to short- (254 nm) and long-wavelength (365 ultraviolet (UV) radiations for different time periods. These irradiated samples were characterized UV–Visible spectroscopy. No significant variation in optical absorbance/transmittance broad (200–365 spectrum is observed with increasing dose. The effect of...

To compare the glomerular filtration rate (GFR) by 99mTc DTPA scan and Cockroft Gault method in unilateral small kidney. The present study was conducted Department of Nuclear Medicine at Sher-i-Kashmir Institute Medical Sciences (SKIMS), India from July 2007 to April 2011. included 47 patients with a diagnosis kidney on ultrasound. Out patients, 21 (44.7%) were males 26 (55.3%) females. Image processing done using camera based methods. GFR automatically calculated software commercially...

Esophageal dysmotility is associated with gastrointestinal in various systemic and neuroregulatory disorders. Hypothyroidism has been reported to be impaired motor function esophagus due accumulation of glycosaminoglycan hyaluronic acid its soft tissues, leading changes contraction relaxation parameters esophagus, particularly the lower esophageal sphincter. In this study we evaluated transit times patients primary hypothyroidism using technique radionuclide scintigraphy.Thirty-one 15...

To know the probability of renal artery stenosis (RAS) in unilateral small kidney and function kidney, which includes glomerular filtration rate, differential function, uptake, Tmax by (99m)Tc diethylenetriaminepentacetic acid (DTPA) base DTPA angiotensin converting enzyme (ACE) inhibition scan. All our patients were subjected to ACE scintigraphy. underwent either computed tomography (CT) angiography magnetic resonance (MR) was done those test deranged. Renal subsequently performed cases...

Melorheostosis, also known as Leri's disease and flowing periosteal hyperostosis, is a rare cause of pain stiffness in limb. The appearance "candle greasing" down one side or several bones the body. We describe case referred to tertiary care center with suspicion renal cell carcinoma diffuse bone metastasis. After reassessment, patient was diagnosed melorheostosis AV malformation. He reassured about benign nature asymptomatic.

One of the commonest causes avascular necrosis bones in patients with renal transplants are glucocorticoids. Early detection and management this complication is crucial to progression prevention collapse femoral heads. In early diagnosis radionuclide bone scintigraphy provides an useful information on aetiology painful hip before changes appear X ray examination. We present a case proved glomerulonephritis taking glucocorticoids difficulty walking pain around joints. A planar whole body...