- Bone health and osteoporosis research
- Bone and Joint Diseases
- Bone health and treatments
- Hip and Femur Fractures
- Vitamin D Research Studies
- Nutrition and Health in Aging
- Bone Metabolism and Diseases
- Parathyroid Disorders and Treatments
- Hemoglobinopathies and Related Disorders
- Body Composition Measurement Techniques
- Pharmacological Effects and Toxicity Studies
- Inflammatory Bowel Disease
- Bone fractures and treatments
- Iron Metabolism and Disorders
- Growth Hormone and Insulin-like Growth Factors
- Radiation Dose and Imaging
- Pituitary Gland Disorders and Treatments
- Microscopic Colitis
- Medical Imaging and Analysis
- Mast cells and histamine
- Orthopaedic implants and arthroplasty
- Advanced X-ray and CT Imaging
- Adrenal and Paraganglionic Tumors
- Neurofibromatosis and Schwannoma Cases
- Infrared Thermography in Medicine
Casa di Cura Columbus
2021-2024
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2014-2024
Vita-Salute San Raffaele University
2020-2024
IRCCS Ospedale San Raffaele
2021-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2004-2021
Ospedale Maggiore
2005-2021
Advisory Board Company (United States)
2021
CHR Verviers
2021
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2021
University of Milan
1990-2014
Abstract The 6th International Conference, “Controversies in Vitamin D,” was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into mechanisms of action suggest links with conditions that do not depend only on reduced solar exposure or diet intake can be detected distinctive noncanonical metabolites. Optimal 25-hydroxyvitamin (25(OH)D) levels remain debated. Varying recommendations from different societies arise...
In primary hyperparathyroidism (PHPT), vertebral fractures (VFx) occur regardless of bone mineral density (BMD) and may depend on decreased quality. Trabecular score (TBS) is a texture measurement acquired during spinal dual-energy X-ray absorptiometry (DXA). Recently, TBS has been proposed as an index micro-architecture.We studied 92 PHPT patients (74 females, age 62.1±9.7 years) 98 control subjects. all at baseline, in 20 surgically treated 10 conservatively after 24 months, TBS, (lumbar...
Abstract Patients with adrenal incidentalomas (AIs) and subclinical hypercortisolism (SH) have increased risk of fracture independent bone mineral density (BMD) possibly due to reduced quality. The trabecular score (TBS) has been proposed as a index microarchitecture. aim the study was investigate TBS in AI. In 102 AI patients, SH diagnosed presence at least two following: (1) urinary free cortisol >70 µg/24 h (193.1 nmol/L); (2) after 1-mg dexamethasone suppression test (1-mg DST)...
Total bone mineral and density modifications were evaluated during fracture healing of long bones in patients with traumatic fractures the lower limbs, using an experimental model based on dual photonabsorptiometry technique. Seven (five males two females; mean age, 19.5 years; range, 17-23 years) tibia fibula midshaft open treated osteosynthesis studied. Dual energy gadolinium-153 was used to measure distal leg loss at a skeletal segment distant from exclude callus formation. (TBM) (BMD)...
Data about endocrine and bone disease in nontransfusion-dependent thalassaemia (NTDT) is scanty. The aim of our study was to evaluate these complications β-TI adult patients.We studied retrospectively 70 patients with mean followup 20 years. recorded included age, gender, haemoglobin ferritin levels, biochemical tests, liver iron concentration (LIC) from T2*, transfusion regimen, chelation, hydroxyurea, splenectomy, mineralization by dual X-ray absorptiometry.Thirty-seven (53%) males 33...
Bone's resistance to fracture depends on several factors, such as bone mass, microarchitecture, and tissue material properties. The clinical assessment of strength is generally performed by Dual-X Ray Photon Absorptiometry (DXA), measuring mineral density (BMD) trabecular score (TBS). Although it considered the major predictor strength, BMD only accounts for about 70% fragility fractures, while remaining 30% could be described "quality" impairment parameters, mainly related...