A5037148193- Immune Response and Inflammation
- Adipose Tissue and Metabolism
- Thermoregulation and physiological responses
- Cancer, Hypoxia, and Metabolism
- Pulmonary Hypertension Research and Treatments
- High Altitude and Hypoxia
- Heat shock proteins research
- Nitric Oxide and Endothelin Effects
- Macrophage Migration Inhibitory Factor
- Genetics, Aging, and Longevity in Model Organisms
- Abdominal vascular conditions and treatments
- Traditional Chinese Medicine Analysis
- Biochemical effects in animals
- Autophagy in Disease and Therapy
- Neuroinflammation and Neurodegeneration Mechanisms
- Aortic aneurysm repair treatments
- Acute Kidney Injury Research
- Trace Elements in Health
- Infectious Aortic and Vascular Conditions
- Vitamin C and Antioxidants Research
- Pregnancy and Medication Impact
- Eicosanoids and Hypertension Pharmacology
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Climate Change and Health Impacts
- Mitochondrial Function and Pathology
Wenzhou Medical University
2024
General Hospital of Guangzhou Military Command
2014-2022
Zhujiang Hospital
2022
Southern Medical University
2022
Background Increasing evidence has revealed that humid heat stress (HHS) causes considerable damage to human health. The cardiovascular system been suggested be the primary target of stress, which results in serious diseases. However, there is still a lack effective approaches for prevention and treatment diseases induced by HHS. Objective Heat-shock proteins (Hsps), especially Hsp70, are reported provide cytoprotection under various stimuli. In present study, we evaluated cytoprotective...
Cerebral ischemia/reperfusion (I/R) can induce neuronal death, particularly in the hippocampal formation (HF). Molecular genetic studies have suggested that activities of transcription factor, hypoxia-inducible factor-1α (HIF-1α), are closely linked to ischemia-induced death. However, mechanisms through which HIF-1α functions remain poorly understood. In this study, primary cortical neurons were subjected oxygen‑glucose deprivation (OGD) establish a cell model OGD/reperfusion (RP). mRNA and...
Background. Tetramethylpyrazine (TMP), a potent anti-free radical and anti-inflammations substance, has been demonstrated to possess direct vessel relaxation property. This study aimed evaluate the effect of TMP treatment in pulmonary hypertension (PH) test hypothesis that prevents or reverses process PH. Methods. Rats (n = 36) injected with 50 mg/kg monocrotaline (MCT) subcutaneously 4 weeks develop PH were then randomized (5 per day) for another weeks. Hemodynamics was evaluated via right...
Heat stress (HS) is commonly used to refer the heat load that an individual subjected due either metabolic heat, or environmental factors, including high temperatures and humidity levels. HS has been reported affect even damage functioning of various organs; overexposure may lead accidental deaths. It suggested cardiovascular system primarily targeted by exposure conditions; HS-induced dysfunction cardiomyocytes, which characterized mitochondrial dysfunction, result in development diseases....