A5045595649- Cardiac Structural Anomalies and Repair
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Cardiac Arrhythmias and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Effects of Exercise
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- ECG Monitoring and Analysis
- Cardiac tumors and thrombi
- Cardiovascular Syncope and Autonomic Disorders
- Congenital Heart Disease Studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Ion channel regulation and function
- Lysosomal Storage Disorders Research
- Pericarditis and Cardiac Tamponade
- Infectious Aortic and Vascular Conditions
- Advanced Breast Cancer Therapies
- Heart Failure Treatment and Management
- Cardiovascular and exercise physiology
- Chronic Lymphocytic Leukemia Research
- Obstructive Sleep Apnea Research
- Glioma Diagnosis and Treatment
Administração Regional de Saúde de Lisboa e Vale do Tejo
2020-2025
Hospital da Senhora da Oliveira Guimarães
2008-2025
Escola Superior de Saúde Egas Moniz
2025
Instituto Português de Oncologia de Coimbra Francisco Gentil
2024
Universidade Nova de Lisboa
2021-2024
Hospital de Clínicas de Porto Alegre
2024
Centro Tecnológico das Indústrias Têxtil e do Vestuário de Portugal
2024
Discovery Air (Canada)
2021-2023
Instituto Português de Oncologia Francisco Gentil
2022-2023
Centro Hospitalar de Trás os Montes e Alto Douro
2009-2015
Multivalvular endocarditis (MVE) is an uncommon presentation and mostly involves mitral aortic valves. Here, we present a case of MVE with unusual bizarre on Halloween night massive degree valve destruction right- left-side involvement requiring emergent surgery. A 51-year-old male patient intravenous drug usage presented anorexia, fever, dyspnea, rapidly progressing to septic shock multiorgan dysfunction. Initial blood cultures detected meticillin-sensitive Staphylococcus aureus, antibiotic...
ABSTRACT Purpose This study explores the effects of anthracycline chemotherapy (AC) on breast cancer patients, focusing changes in body composition, advanced echocardiographic parameters at rest and during exercise, biomarkers; subsequently assesses whether these are associated with impaired cardiorespiratory fitness (CRF). Methods In this prospective study, we evaluated women early‐stage undergoing AC three visits: before AC, 1 month after, 6 months post‐AC. Results The included 32 cancer,...
Abstract Introduction Timely differential diagnosis between hypertrophic cardiomyopathy (HCM), Fabry (FC) and wild-type transthyretin cardiac amyloidosis (ATTR-CA) is crucial for appropriate treatment family screening. Right ventricle (RV) involvement common in these diseases, making the systematic RV assessment essential. Two-dimensional speckle-tracking echocardiography (2D-STE) offers potential precise myocardial mechanics evaluation, however its utility distinguishing conditions remains...
Secondary mitral regurgitation (SMR) is associated with increased hospitalizations and mortality. Clinical trials comparing valve transcatheter edge-to-edge repair (M-TEER) guideline-directed medical therapy (GDMT) show conflicting results, but the RESHAPE-HF2 trial offers new insights. This study aims to assess M-TEER effect in addition GDMT reducing all-cause mortality, cardiovascular death, heart failure (HHF) patients SMR when compared alone. On September 2, 2024, PubMed, Cochrane...
Abstract Introduction Coronary artery disease causes 4000 deaths per year in Portugal, but compliance with recommendations of the European Society Cardiology for timely assessment and treatment may reduce morbidity mortality. Delays can be identified reduced. Objective To assess association between presence electrocardiography technicians a hospital emergency room target times recommended by care patients acute myocardial infarction. Methods Clinical records admitted to an infarction...
<title>Abstract</title> Following the death of an 83-year-old man from district Bragança, in north-eastern Portugal due to Crimean-Congo haemorrhagic fever (CCHF), a serological survey was conducted investigate domestic and wild ruminants. The included samples cattle(n=94), sheep(n=30), goats(n=4), red deer(n=10) collected within affected region neighbouring areas where human case reported. CCHF antibodies were detected serum sheep, cattle deer, corresponding seropositivity rates 3.33%,...
ABSTRACT Background Behavioural cognitive factors, like kinesiophobia and coping skills hypervigilance, may contribute to a worse prognosis of TMD symptoms. However, there is lack evidence about the prevalence relationship hypervigilance with TMD. Objective This study aimed assess associations in Methods The sample consisted 233 participants, divided into group (133) control (100). following instruments were used: diagnostic criteria for temporomandibular disorders (DC/TMD), Pain Vigilance...
Cardioneuroablation (CNA), a technique based on radiofrequency ablation of cardiac vagal ganglia, was developed to treat recurrent vasovagal syncope (VVS) with predominant cardioinhibitory component, as an alternative pacemaker implantation. The aim our study evaluate the safety and success rate CNA guided by extracardiac stimulation in patients highly symptomatic VVS.Prospective who underwent anatomically at two cardiology centers. All had history component refractory conventional measures....
Real-world (RW) data may provide valuable information on the effectiveness and safety of medicines, which is particularly relevant for clinicians, patients third-party payers. Evidence palbociclib plus fulvestrant scarce, highlights need additional studies. The aim this study was to evaluate in advanced breast cancer (ABC).We conducted a population-based retrospective cohort cases interest were identified through Portuguese National Cancer Registry database sources. Patients aged≥18 years,...
Detection of right heart thrombi (RHT) in the context pulmonary thromboembolism (PE) is uncommon (4–18%) and increases risk mortality beyond presence PE alone. Type A are serpiginous highly mobile thought to be originated from large veins captured in-transit within heart. Optimal management RHT still uncertain. 79-year-old woman, with a history recent total hysterectomy adnexectomy Wells procedure, presented emergency department following an episode syncope. Computed tomography revealed...
New drugs for locally advanced or metastatic breast cancer have led to clinical benefits, aside with increasing costs healthcare systems. The current financing model health technology assessment (HTA) privileges real-world data. As part of the ongoing HTA, this study aimed evaluate effectiveness palbociclib aromatase inhibitors (AI) and compare it efficacy reported in PALOMA-2.A population-based retrospective exposure cohort was conducted including all patients initiating treatment Portugal...
Brugada syndrome (BrS) is a channelopathy associated with ventricular arrhythmias and sudden cardiac death. In patients at high risk of death, an implantable cardioverter-defibrillator indicated. Subcutaneous cardioverter-defibrillators (S-ICDs) are alternative to transvenous systems, reduced infection complications system extraction or explantation. To test electrocardiographic eligibility for S-ICD placement after exercise stress testing (EST) in BrS. The sample included 35 consecutive...
Monotherapy with aromatase inhibitors and fulvestrant were the standard-of-care for hormone receptor-positive (HR+)/human epidermal growth factor receptor-type2 negative (HER2-) advanced breast cancer, before integration of cyclin-dependent kinase 4/6 inhibitors. Effectiveness data is essential regulatory action, but little known about real-world use fulvestrant. A retrospective cohort study was conducted resorting to from a cancer registry identify adult women HR+/HER- exposed or (31 May...
To evaluate the prevalence of TTR amyloid cardiomyopathy (ATTR-CM) in severe aortic stenosis (SAS) patients, and to determine independent predictors major adverse events (MAE).
Cardiomyopathy is a manifestation of mitochondrial cytopathies, but rarely constitutes the dominant feature, especially in adults. We report case 59-year-old male with personal and maternal history diabetes deafness, who presented cardiomyopathy kidney disease. diagnosed patient as having cytopathy resulting from 3243A>G mutation on tRNA<sup>Leu(UUR)</sup> gene DNA. The family history, broad spectrum clinical manifestations fluctuant course provided clues to diagnosis. discuss...
We report the case of a 37-year-old male patient admitted to cardiac intensive care unit for acute pulmonary edema. He had history excessive alcoholic consumption and viral syndrome in preceding 10 days. A transthoracic echocardiogram revealed severe biventricular dysfunction, mild dilatation left heart chambers, right chambers. Nonsustained ventricular tachycardia with bundle branch block morphology was detected during electrocardiographic monitoring. In follow-up, he underwent...
A 39-year-old male was admitted in the emergency room with chest pain. He had been given second dose of Pfizer-BioNTech COVID-19 vaccine 3 days before. The patient denied taking any other medication beyond usual. didn't feel sick previous days/weeks. Laboratory studies revealed elevated serum levels troponin and C-reactive protein. An autoantibody screen a serologic panel to detect common viruses were negative. cardiac MRI showed myocardial edema/inflammation confirmed diagnosis...