A5019964809- Herpesvirus Infections and Treatments
- Toxoplasma gondii Research Studies
- HIV Research and Treatment
- interferon and immune responses
Inserm
2023-2025
Université Grenoble Alpes
2023-2025
Centre National de la Recherche Scientifique
2023-2025
Institut de Biosciences et Biotechnologies
2023
Institut pour l'avancée des biosciences
2023
Unit of Virus Host Cell Interactions
2023
Abstract Sexual reproduction of Toxoplasma gondii , confined to the felid gut, remains largely uncharted owing ethical concerns regarding use cats as model organisms. Chromatin modifiers dictate developmental fate parasite during its multistage life cycle, but their targeting stage-specific cistromes is poorly described 1,2 . Here we found that transcription factors AP2XII-1 and AP2XI-2 operate tachyzoite stage, a hallmark acute toxoplasmosis, silence genes necessary for merozoites, stage...
Sexual reproduction of