- Market Dynamics and Volatility
- Asymmetric Synthesis and Catalysis
- Financial Markets and Investment Strategies
- Energy, Environment, Economic Growth
- Neuroscience and Neuropharmacology Research
- Credit Risk and Financial Regulations
- Banking stability, regulation, efficiency
- Chemical Synthesis and Analysis
- Synthetic Organic Chemistry Methods
- Monetary Policy and Economic Impact
- COVID-19 Pandemic Impacts
- Bioactive Compounds and Antitumor Agents
- Molecular Sensors and Ion Detection
- Coordination Chemistry and Organometallics
- Financial Distress and Bankruptcy Prediction
- Cancer therapeutics and mechanisms
- Carbohydrate Chemistry and Synthesis
- Cyclopropane Reaction Mechanisms
- Complex Systems and Time Series Analysis
- Energy, Environment, and Transportation Policies
- Pharmacological Receptor Mechanisms and Effects
- Lipoproteins and Cardiovascular Health
- Synthesis and Catalytic Reactions
- Axial and Atropisomeric Chirality Synthesis
- Pharmacogenetics and Drug Metabolism
University of Castilla-La Mancha
2017-2024
Zayed University
2020
Bridge University
2020
Eli Lilly (Spain)
1998-2013
Eli Lilly (United States)
2000-2005
Universidad Autónoma de Madrid
1993-1995
Consejo Superior de Investigaciones Científicas
1993
This paper explores the dynamic return and volatility connectedness for three most relevant agricultural livestock commodity indexes (Softs, Grains Livestock) a media sentiment index as Coronavirus Media Coverage Index (MCI). To that purpose, we apply fresh time-varying parameter vector autoregression methodology during sample period between 1 January 2020 30 April 2021, is, covering waves of COVID-19 pandemic crisis. Interesting results are found in this research. First, total fluctuate...
Lipoprotein(a) (Lp(a)), an independent, causal cardiovascular risk factor, is a lipoprotein particle that formed by the interaction of low-density (LDL) and apolipoprotein(a) (apo(a))
This study examines the intraday volatility connectedness between FTT token and major cryptocurrencies (altcoins stablecoins) surrounding FTX bankruptcy. Intraday hourly time series are estimated by using a mcGARCH model then applied to provide network measures via TVP-VAR model. Our results suggest that FTX's bankruptcy has increased overall in crypto markets. Surprisingly, we reveal stablecoins most affected tokens after collapse. plays key role as main net contributor system (confirmed...
This paper investigates the connectedness between crude oil prices and several financial stock markets from January 2000 to February 2023, applying a Dynamic Conditional Correlation Skew Student Copula model index by Diebold Yilmaz (2012). The Kendall's Tau correlation findings show that prior Global Finance Crisis, equity were less linked BRENT than after crisis, likely because of economic growth reducing importance prices. However, late 2008 global uncertainty due various crises conflicts...
This paper explores the static and dynamic connectedness between oil price shocks (risk, demand supply shocks) Spanish sector equity indices from January-2000 to July-2019. We document sizable system-wide variables under study. Among shocks, risk are main transmitter (receiver) of (from) system overall net receiver system. indices, Industrials, Financials, Utilities Telecommunications as major transmitters whereas; Consumer Goods, Technology, Retail receivers. The changes over time sectors....
Abstract This study aims to examine the impact of different waves COVID-19 pandemic on connectedness BRICS (Brazil, Russia, India, China, and South Africa) term structure interest rates its components (level, slope curvature). For that purpose, this research applies time-varying parameter vector autoregression (TVP-VAR) approach in order assess direction spillovers among countries factors measure their contribution system. Our results show total changes over time, level curvature persists...
This paper aims to assess the dynamic linkages between crude oil futures contracts, renewable energy indices, carbon credit indices and several US sector market by applying DECO-GARCH model connectedness index of Diebold Yilmaz (2012). The analysis is conducted on a daily data sample from August 2014 February 2024 performed at both aggregated disaggregated levels. revealed that correlation variables was lower before periods stress, such as COVID-19 crisis Russian–Ukrainian conflict well...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of Enantiomerically Pure 4-Substituted Glutamic Acids and Prolines: General Aldol Reaction Pyroglutamate Lactam Lithium Enolate Mediated by Et2O.cntdot.BF3Jesus Ezquerra, Concepcion Pedregal, Belen Yruretagoyena, Almudena Rubio, M. Carmen Carreno, Ana Escribano, Jose Luis Garcia RuanoCite this: J. Org. Chem. 1995, 60, 9, 2925–2930Publication Date (Print):May 1, 1995Publication History Published online1 May 2002Published inissue 1...
Purpose This paper aims to examine the dynamic return and volatility connectedness for six major industrial metals (tin, lead, nickel, zinc, copper aluminium) coronavirus media coverage index (MCI). Design/methodology/approach To that purpose, this study applies fresh time-varying parameter vector autoregression methodology (TVP–VAR model) during sample period between 2 January, 2020, 16 April, 2021, is, covering three waves of COVID-19 pandemic crisis. Findings study’s results show...
Amino diacid 3, a highly selective competitive GluR5 kainate receptor antagonist, exhibited high affinity and selectivity over other glutamate receptors. Its diethyl ester prodrug 4 was orally active in two models of migraine: the neurogenic dural plasma protein extravasation model nucleus caudalis c-fos expression model. These data suggest that antagonist might be an efficacious antimigraine therapy with novel mechanism action.
Amino acids 5 and 7, two potent selective competitive GluR5 KA receptor antagonists, exhibited high affinity over other glutamate receptors. Their ester prodrugs 6 8 were orally active in three models of pain: reversal formalin-induced paw licking, carrageenan-induced thermal hyperalgesia, capsaicin-induced mechanical hyperalgesia.
Abstract This paper explores the dynamic return and volatility connectedness for three most relevant agricultural commodity markets (Soft, Grain Livestock) Coronavirus Media Coverage Index (MCI) extracted from RavenPack. In concrete, we apply fresh TVP-VAR methodology proposed by Antonakakis Gabauer (2017) during sample period between January 22, 2020 July 31, 2020, that is in context of COVID-19 pandemic crisis. Interesting results are found this research. First, total fluctuates over time,...
Enantiomerically pure (2S,4R)-4-substituted glutamic acids were prepared and tested for homomeric GluR5 GluR6 kainate subtype receptor affinity. Some of the 4-cinnamyl analogues showed high selectivity potency (K(i) < 25 nM) receptors. The greatest achieved with 3-(2-naphthyl)prop-2-enyl compound. This compound, LY339434, has negligible activity at AMPA receptors GluR1, -2, -4 -6. Although, LY339434 shows agonist NMDA in cultural hippocampal neurons (approximate EC(50) 2.5 microM), we...
We examine the role of five liquidity dimensions in U.S. corporate bond market from a broad set proxies. Based on observed different level shown by investment-grade and high-yield bonds, we analyze ability several proxies to classify bonds within these two main credit rating classes. Our findings show that, at individual level, all tightness-based metrics outperform other measures. In this way, few measuring transaction costs can help detect whose behaves similarly that bonds. At dimension...