A5046649334- MicroRNA in disease regulation
- Cancer-related cognitive impairment studies
- Cancer Research and Treatments
- Functional Brain Connectivity Studies
- RNA modifications and cancer
- Nuclear Receptors and Signaling
- Epigenetics and DNA Methylation
- Ferroptosis and cancer prognosis
- Circular RNAs in diseases
- Cancer, Hypoxia, and Metabolism
- Dementia and Cognitive Impairment Research
Ningxia Medical University General Hospital
2025
Ningxia Medical University
2023-2025
Nanchang University
2022
Jiangxi Provincial Academy of Medical Sciences
2022
First Affiliated Hospital of Nanchang University
2022
<title>Abstract</title> Gastric Carcinoma (GC) is the world’s third-highest cause of death by cancer. Cuproptosis a newly discovered programmed cell dependent on overload copper-induced mitochondrial respiration dysregulation. We speculated this regulatory (RCD) mechanism might serve as potential prognostic predictors and therapy for GC patients. The expression mutation patterns 12 cuproptosis-related genes were systematically evaluated in training group. Through unsupervised clustering...
Gastric cancer is the fifth most common neoplasm and fourth reason for mortality globally. Incidence rates are highly variable dependent on risk factors, epidemiologic carcinogenesis patterns. Previous studies reported that Helicobacter pylori (H. pylori) infection one strongest known factor gastric cancer. USP32 a deubiquitinating enzyme identified as potential associated with tumor progression key player in development. On other hand, SHMT2 involved serine-glycine metabolism to support...
The aim of this study was combining multi-level resting-state functional magnetic resonance imaging (rs-fMRI) features with machine learning method to distinguish breast cancer patients chemotherapy-related subjective cognitive complaints (SCC) from non-chemotherapy (BC) and healthy controls (HC). Forty subjects in SCC group, forty-nine BC group thirty-four HC were recruited underwent rs-fMRI scanning. Based on the anatomical automatic labeling brain atlas, metrics all included connectivity,...
To explore the specific mechanism by which circ_0084043/miR-31-5p regulates high mobility group AT-hook 1 (HMGA1) and thus participates in atherosclerosis (AS). Carotid plaque tissues, diseased vascular tissue, corresponding normal tissue from areas adjacent to plaques were collected 49 AS patients between September 2020 2023. Quantitative reverse transcription polymerase chain reaction (qRT-PCR) was used determine circ_0084043 expression. The proliferation, migration, invasion of smooth...
Chemotherapy-related cognitive impairment (CRCI), especially subjective complaints (SCC), had been often reported in breast cancer survivors, which affects their life and work. The identification of biomarkers for early diagnosis prognosis prediction SCC remains a crucial challenge important clinical implications. resting-state functional magnetic resonance imaging (rs-fMRI) has widely used to detect abnormalities brain activity CRCI. machine learning method combined with rs-fMRI features...