A5076610239- Nanoplatforms for cancer theranostics
- Atmospheric chemistry and aerosols
- Medical Imaging Techniques and Applications
- Mass Spectrometry Techniques and Applications
- Gas Sensing Nanomaterials and Sensors
- Peptidase Inhibition and Analysis
- Air Quality and Health Impacts
- Air Quality Monitoring and Forecasting
- Advanced Chemical Sensor Technologies
- Cancer, Stress, Anesthesia, and Immune Response
- Advanced biosensing and bioanalysis techniques
Shanghai Jiao Tong University
2015-2024
Among all characteristics of the tumor microenvironment (TME), which are caused by abnormal proliferation solid tumors, extracellular acidity is an important indicator for malignancy grading. pH-low insertion peptides (pHLIPs) adopted to discern acidic TME. To date, different imaging agents including fluorescent, positron emission tomography (PET), single photon computed (SPECT), and magnetic resonance (MR) contrast with pHLIPs target TME have been used image various models successfully. In...
Cancer which causes high mortality globally threatens public health seriously. There is an urgent need to develop tumor-specific near-infrared (NIR) imaging agents achieve precise diagnosis and guide effective treatment. In recent years, probes that respond acidic environments such as endosomes, lysosomes, or tumor microenvironments (TMEs) are being developed. However, because of their nonspecific internalization by both normal cells, resulting in a poor signal-to-noise ratio diagnosis,...
2015年7月至2016年3月在台州市采集504个PM 2.5 样品，利用电感耦合等离子体发射光谱仪和原子荧光光度计分析样品中的19种无机元素，利用离子色谱和热光碳分析仪分别分析8种水溶性离子和2种碳组分有机碳（OC）和元素碳（EC）的质量分数，研究不同功能区环境空气PM 及其化学组分的污染特征.结果表明，台州市环境空气PM 年均质量浓度为（45.3±20.1） μ g·m -3 ，季节变化规律为冬季>春季>秋季>夏季，空间变化规律为工业园区>商住区>自然保护区.19种无机元素占PM 总量的9.78%，主要元素为Na、K、Ca、Si、Zn、Al、Mg和Fe.富集因子分析结果表明，台州市无机元素的主要污染源包括道路交通尘、燃煤尘、建筑扬尘以及海盐粒子.采样期间8种水溶性离子总质量浓度为（26.50±5.86） ，SO 4 2- 、NO 3 - 和NH + 占PM 总量的（41.96±8.59）%.Cl 离子质量分数为工业园区>商住区>自然保护区，SO 离子质量分数水平在3个功能区相近.OC和EC的年均浓度分别为（10.04±2.08）和（3.27±0.80）...