A5084984355- Circadian rhythm and melatonin
- Mental Health Research Topics
- Sleep and related disorders
- Psychological and Temporal Perspectives Research
- Olfactory and Sensory Function Studies
- Tryptophan and brain disorders
- Spaceflight effects on biology
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health, psychology, and well-being
- Treatment of Major Depression
- Bipolar Disorder and Treatment
- Child and Adolescent Psychosocial and Emotional Development
- Behavioral Health and Interventions
- Photoreceptor and optogenetics research
- Light effects on plants
- Workplace Health and Well-being
- Neuroendocrine regulation and behavior
- Personality Disorders and Psychopathology
- Urban Green Space and Health
- Outdoor and Experiential Education
- Eating Disorders and Behaviors
- Agriculture Sustainability and Environmental Impact
- Obsessive-Compulsive Spectrum Disorders
- Medicinal Plant Extracts Effects
- Paranormal Experiences and Beliefs
University of Groningen
2014-2024
University Medical Center Groningen
2015-2024
De Hoogstraat Revalidatie
2024
Pine Rest Christian Mental Health Services
2022
Hospital Universitario de San Vicente Fundación
2022
Universidad de Antioquia
2022
University Hospital Carl Gustav Carus
2018
University of California, Irvine
2018
University of Washington
2018
Psychiatric Medicine Associates
2018
Background The chronotype, being a morning or an evening type, can influence individual's psychological health. Studies have shown link between depressed mood and type; however, most studies used symptom scales not diagnostic criteria, confounding factors such as sleep patterns somatic health often been considered. This study aims to examine the association chronotype depressive (major disorder (MDD), dysthymia) anxiety (generalized disorder, panic agoraphobia, social phobia) disorders...
Photoreceptor cells containing melanopsin play a role in the phase-shifting effects of short-wavelength light. In previous study, we compared standard light treatment (SLT) SAD with using blue-enriched white (BLT). Both treatments used same illuminance (10 000 lux) and were equally highly effective. It is still possible, however, that neither newly-discovered photoreceptor cells, nor biological clock major therapeutic on SAD. Alternatively, these may at least be partly mediated by receptor...
Social jetlag, the misalignment between internal clock and socially required timing of activities, is highly prevalent, especially in people with an evening chronotype hypothesized to be related link major depressive disorder. Although social jetlag has been linked symptoms non-clinical samples, it never studied patients disorder (MDD). This study aimed healthy controls, further examine symptomatology. Patients a diagnosis MDD (n = 1084) controls 385), assessed clinical interview, were...
Background Chronotype is an individual's preferred timing of sleep and activity, often referred to as a later chronotype (or evening-type) or earlier morning-type). Having evening associated with more severe depressive anxiety symptoms. Based on these findings it has been suggested that stable construct vulnerability develop disorders. To examine this, we test the stability over 7 years, its longitudinal association change in severity Methods Data 1,417 participants and/or disorder diagnosis...
Recent research has emphasized that the human circadian rhythm system is differentially sensitive to short wavelength light. Light treatment devices using efficient light-emitting diodes (LEDs) whose output relatively concentrated in wavelengths may enable a more convenient effective therapy for Seasonal Affective Disorder (SAD). The efficacy of LED light device SAD was tested randomized, double-blind, placebo-controlled, multi-center trial. Participants aged 18 65 with (DSM-IV major...
One of the most frequently investigated hypotheses pathophysiology underlying Seasonal Affective Disorder (SAD) is a disturbance circadian rhythms. Since system as well other non-visual effects especially sensitive to blue light, new light therapy device with enriched polychromatic was tested for its efficacy treat SAD.Within one winter 52 patients were treated in three conditions: 30 min full spectrum (9000 lx, 5000 K), blue-enriched 17,000 or 20 light. The study lasted 22 days 10...
Despite the advances of recent decades, there is still an urgent need for antidepressants with improved efficacy, safety and tolerability. Agomelatine a new antidepressant innovative pharmacological profile. It first melatonergic antidepressant, potent agonist melatonin receptors (MT1 MT2) 5-HT2C antagonist properties. The efficacy 25 mg/day agomelatine in treating major depressive disorder (MDD) has been demonstrated number placebo-controlled studies. Evidence improvement symptoms was...
Little is known about seasonality of specific depressive symptoms and anxiety in different patient populations. This study aims to assess seasonal variation a primary care population across participants who were classified diagnostic groups 1) healthy controls 2) patients with major disorder, 3) any disorder 4) depression disorder.Data used from the Netherlands Study Depression Anxiety (NESDA). First, 5549 NESDA recruitment Kessler-10 screening questionnaire was data analyzed season...
Background Sixty-eight patients with seasonal affective disorder participated in a 10 000-lux light treatment study which two questions were addressed: do response rates differ when the is applied at different times of day and does short-term rank ordering morning evening influence rates? Method Three groups received 4-day treatment: (I) (8.00–8.30 a.m., n = 14), (II) afternoon (1.00–1.30 p.m., 15) or (III) 12). Two additional days followed by (IV, 13) vice versa (V, 14). Results Response...
Background Seasonal changes in mood and behavior are considered to be common the general population patients with psychiatric disorders. However, several studies this seasonality could not demonstrated. The present study examined self-attributed of depressive symptoms among a lifetime diagnosis disorder (D), an anxiety (A), comorbid (DA), healthy controls (HC). Methods CIDI was used establish diagnoses according DSM-IV criteria 2,168 participants Netherlands Study Depression Anxiety (NESDA)....
Seasonal affective disorder (SAD) is characterized by recurrent episodes of major depression with a seasonal pattern, treated light therapy (LT). Duration differs. This study investigates retrospectively whether single week LT as effective two weeks, males and females respond differently, there an effect expectations assessed before treatment.83 women, 25 men received either one-week (n=42) or weeks (n=66) were included in three studies. Before LT, patients׳ on response assessed.Depression...
The discovery of a novel photoreceptor in the retinal ganglion cells with highest sensitivity 470-490 nm blue light has led to research on effects short-wavelength humans. Several studies have explored efficacy monochromatic or blue-enriched treatment SAD. In this study, comparison been made between broad-wavelength without ultraviolet (UV) wavelengths compared narrow-band sub-syndromal seasonal affective disorder (Sub-SAD). 15-day design, 48 participants suffering from Sub-SAD completed...
Morning light exposure administered as simulated dawn looks a promising method to treat Seasonal Affective Disorder, but it may moreover help with resetting the inaccurate organisation of body clock functions relative sleep occurring in winter among people general. Disturbances patterns are common and compromise wellbeing even short term. Our hypothesis was that could improve subjective quality during winter. A community-based trial 100 volunteer subjects provided simulators. Study period...
Abstract Background Bipolar disorder is associated with circadian disruption and a high risk of suicidal behavior. In previous exploratory study patients bipolar I disorder, we found that history suicide attempts was differences between winter summer levels solar insolation. The purpose this to confirm finding using international data from 42% more collection sites 25% countries. Methods Data analyzed were 71 prior new in 40 countries at wide range latitudes. analysis included 4876 45% than...
Objectives Societal restrictions imposed to prevent transmission of COVID-19 may challenge circadian-driven lifestyle behaviours, particularly amongst those vulnerable mood disorders. The overarching aim the present study was investigate hypothesis that, in routine-disrupted environment COVID-19, a sample people living with disorders, greater social rhythm disruption would be associated more severe symptoms. Methods We conducted two-wave, multinational survey 997 participants [Formula: see...