Karpov IuA

ORCID: 0000-0003-1480-0458
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About
Contact & Profiles
Research Areas
  • Blood Pressure and Hypertension Studies
  • Cardiac Imaging and Diagnostics
  • Lipoproteins and Cardiovascular Health
  • Hormonal Regulation and Hypertension
  • Healthcare Systems and Public Health
  • Coronary Interventions and Diagnostics
  • Cardiovascular Disease and Adiposity
  • Neurological Disorders and Treatments
  • Heart Rate Variability and Autonomic Control
  • Cardiovascular Health and Disease Prevention
  • Cardiovascular Syncope and Autonomic Disorders
  • Pharmacology and Obesity Treatment
  • Cardiac Health and Mental Health
  • Systemic Lupus Erythematosus Research
  • Eicosanoids and Hypertension Pharmacology
  • Cardiovascular Function and Risk Factors
  • Peripheral Artery Disease Management
  • Cancer, Lipids, and Metabolism
  • Acute Myocardial Infarction Research
  • Atherosclerosis and Cardiovascular Diseases
  • Advanced MRI Techniques and Applications
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Diabetes Treatment and Management
  • Atrial Fibrillation Management and Outcomes
  • Ultrasound and Hyperthermia Applications

National Medical Research Center of Cardiology
2017-2025

Sechenov University
2020-2023

Plekhanov Russian University of Economics
2021-2022

Ministry of Health of the Russian Federation
2005-2020

National Statistical Service of the Republic of Armenia
2020

Lomonosov Moscow State University
2019

Institute of Experimental Cardiology
2007-2018

Chelyabinsk State Medical Academy
2017

National Research Center for Preventive Medicine
2016

VA Nasonova Scientific Research Institute of Rheumatology
2016

The Russian Society of Cardiology (RKO) With the participation of: National for Study Atherosclerosis (NOA), Association Endocrinologists (RAE), Cardiosomatic Rehabilitation and Secondary Prevention (RosOKR), Scientific Medical Therapists (RNMOT), Eurasian Cardiologists, (EAT), Gerontologists Geriatricians

10.15829/1560-4071-2023-5471 article EN cc-by Russian Journal of Cardiology 2023-06-03

Objective To compare the efficacy of indapamide sustained release (SR) 1.5 mg and enalapril 20 at reducing left ventricular mass index (LVMI) in hypertensive patients with hypertrophy (LVH). Design The LIVE study (left regression, versus enalapril) was a 1 year, prospective, randomized, double-blind study. For first time, committee validated LVH before inclusion, provided on-going quality control during study, performed an end-study reading all echocardiograms blinded to sequence. Setting...

10.1097/00004872-200018100-00015 article EN Journal of Hypertension 2000-10-01

Few data are available comparing the effects of monotherapy and combination therapy on target organ damage. The PICXEL study compared efficacy a strategy based first-line with perindopril/indapamide versus enalapril in reducing left ventricular hypertrophy (LVH) hypertensive patients.In this 1-year multicentre randomized double-blind study, patients received an increasing dosage (n = 284) or 272). Changes blood pressure echocardiographic measures LVH were assessed from baseline to end...

10.1097/01.hjh.0000187253.35245.dc article EN Journal of Hypertension 2005-10-05

Disclaimer РThe EAC/RNAS Guidelines represent the views of EAC and RNAS, were produced after careful consideration scientific medical knowledge, evidence available at time their publication. The RNAS is not responsible in event any contradiction, discrepancy, and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies. Health professionals are encouraged take fully into...

10.38109/2225-1685-2020-2-6-29 article EN cc-by-nc-sa Eurasian heart journal 2020-05-26

Data regarding the prevalence of hypertriglyceridemia in Russian population are lacking, despite triglyceride (TG)-mediated pathways being causal cardiovascular disease. The mixed dyslipidemia and severe (PROMETHEUS) was undertaken to address this gap. This an observational, cross-sectional retrospective study. from adults with a full/partial lipoprotein record who had blood analyses done at INVITRO laboratory Russia between January 1, 2011 December 31, 2013 were analyzed. primary endpoint...

10.1186/s12933-015-0268-2 article EN cc-by Cardiovascular Diabetology 2015-08-24

The high prevalence of persistent dyslipidemia in primary and specialized care patients treated with statins justifies the need to identify its reasons develop recommendations on treatment optimization. At present, Russian studies focusing achievement target lipid levels remain scarce, which emphasizes importance problem further investigation. Aim. Cross-sectional epidemiological study assessed statin-treated analysed predictors levels. Material methods. profile parameters were 1586...

10.15829/1728-8800-2012-4-70-78 article EN cc-by CARDIOVASCULAR THERAPY AND PREVENTION 2012-08-20

The article presents a review of the current approaches to testing and treatment HCV infection in prison populations. It provides data from literature sources, including research articles, as well clinical guidelines European (2020) American (2023) Liver Disease Societies. Particular attention is paid patients prison, this contributes elimination community.

10.51922/1818-426x.2025.1.26 article EN Medical Journal 2025-01-01

The aim of the expert council "First star duo telmisartan and indapamide in Russian Federation", dedicated to introduction a new fixed-dose combination (modified-release tablets) into clinical practice was formulate an opinion on potential use novel treatment hypertensive patients.

10.15829/1560-4071-2025-6249 article EN cc-by Russian Journal of Cardiology 2025-01-13

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10.15829/1728-8800-2025-4244. article cc-by CARDIOVASCULAR THERAPY AND PREVENTION 2025-01-21

The presented expert paper discusses the high prevalence of hypercholesterolemia (HCH) in Russia. Insufficient use lipid-lowering therapy both primary and secondary prevention is indicated. Failure to achieve target level low-density lipoprotein cholesterol (HC) low adherence (especially long-term) patients hypolipidemic drugs remains a serious problem real clinical practice. Statins are class widely prescribed that first choice treatment HCV combined hyperlipidemia (GLP) with proven...

10.17816/cs676903 article EN cc-by-nc Cardiosomatics 2025-04-15

The role of various inflammatory mechanisms and oxidative stress in the development atherosclerosis arterial hypertension (AH) has been increasingly acknowledged during recent years. Hypertension per se or factors that cause along with other complications lead to infiltration activated leukocytes vascular wall, where these cells contribute injury by releasing cytokines, oxygen radicals, toxic mediators. However, molecular underlying leukocyte activation at transcriptional level AH are still...

10.1196/annals.1378.077 article EN Annals of the New York Academy of Sciences 2006-12-01

Subclinical atherosclerosis is an initial, latent stage of chronic progressing arterial inflammation. Destabilisation asymptomatic, hemodynamically non-significant atherosclerotic plaques (AP) could lead to myocardial infarction, stroke, or sudden death. Since the assessment AP stability problematic in real-world clinical settings, risk stratification should, at least, account for presence subclinical atherosclerosis. In 600 ambulatory patients from Moscow City Western Administrative Okrug...

10.15829/1728-8800-2012-3-82-86 article EN cc-by CARDIOVASCULAR THERAPY AND PREVENTION 2012-06-20

Цель обзора: освещение основных положений обновленных рекомендаций Европейского кардиологического общества по реваскуляризации миокарда, касающихся чрескожных коронарных вмешательств (ЧКВ) при стабильной ишемической болезни сердца (ИБС

10.31550/1727-2378-2019-157-2-6-11 article RU Doctor Ru 2019-01-01

The article presents the main results of Russian post-marketing multicenter open-label program TRICOLOR (Triple fixed-dose combination in treatment hypertension). Aim. To evaluate antihypertensive efficacy and tolerability triple amlodipine/indapamide/perindopril combination, as well adherence hypertensive (HTN) patients to this therapy actual clinical practice. Material methods. enrolled 1247 outpatients aged 18 79 both sexes with essential HTN. All included study receive amlodipine/...

10.15829/1560-4071-2020-4130 article EN cc-by Russian Journal of Cardiology 2020-11-18

With a high prevalence in the Russian population and insufficient effectiveness of treatment, hypertension remains poorly controlled cardiovascular risk factor, including due to low compliance patients. Noncompliance is large number factors, some which were studied post-hoc analysis observational STIL’ TRICOLOR studies. It demonstrated that fixed-dose combinations antihypertensive drugs can make significant contribution solving such complex problem as compliance.

10.15829/1560-4071-2022-5202 article EN cc-by Russian Journal of Cardiology 2022-08-25

D-dimer, plasminogen activator inhibitor (PAI-1) activity at rest and after exercise, tissue (t-PA) exercise were measured in venous blood 88 patients with atherosclerotic lesions of various degrees. According to clinical symptoms, coronary angiography (CAG), ultrasound Doppler signal duplex colour scanning carotid arteries their branches, subclavian, vertebral peripheral the lower limbs, divided into four groups. Group 1, 16 men without CAG signs lesions; group 2, 27 CAG-confirmed artery...

10.1093/eurheartj/16.1.38 article EN European Heart Journal 1995-01-01

Abstract Introduction Heart rate (HR) reduction is an integral part of antianginal therapy, but many patients do not reach the guideline-recommended target less than 60 bpm despite high use beta-blockers (BB). Failure to uptitrate BB doses may be partly blame. To explore other options for lowering HR and improving angina control, CONTROL-2 was initiated compare efficacy tolerability combination BBs with ivabradine versus uptitration maximal tolerated dose, in stable angina. Methods This...

10.1007/s12325-018-0681-5 article EN cc-by Advances in Therapy 2018-03-01

Tactics for the management of patients with hypertriglyceridemia (HTG) is provided in conclusion Advisory Board. It demonstrated that HTG quite prevalent excessive body weight and an important component residual risk. creates additional conditions progression atherosclerosis, thus it recommended to test triglyceride high, very high extremely cardiovascular The indication pharmacological treatment reduce triglycerides concentration their level more than 2.3 mmol/l. Statins are drugs choice...

10.20996/1819-6446-2019-15-2-282-288 article EN cc-by Rational Pharmacotherapy in Cardiology 2019-05-06
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