A5008698512- Nitric Oxide and Endothelin Effects
- Algal biology and biofuel production
- Transplantation: Methods and Outcomes
- Antioxidant Activity and Oxidative Stress
- Cardiac Ischemia and Reperfusion
- Cardiovascular Health and Disease Prevention
- Biodiesel Production and Applications
- Cardiovascular Disease and Adiposity
- Cardiovascular Issues in Pregnancy
- Atherosclerosis and Cardiovascular Diseases
- Aquatic Ecosystems and Phytoplankton Dynamics
- Photosynthetic Processes and Mechanisms
- Cardiovascular Function and Risk Factors
- Peroxisome Proliferator-Activated Receptors
- Cardiovascular and Diving-Related Complications
- Vitamin K Research Studies
- Lipid metabolism and disorders
- Real estate and construction management
- Hydrogen's biological and therapeutic effects
- Renin-Angiotensin System Studies
- Coronary Interventions and Diagnostics
- Pharmacological Effects and Assays
- Receptor Mechanisms and Signaling
- Bioactive Natural Diterpenoids Research
- Spectroscopy and Quantum Chemical Studies
Forschungszentrum Jülich
2016-2017
QB3
2010
University of California, Berkeley
2010
Düsseldorf University Hospital
2009
San Francisco General Hospital
2009
Brigham and Women's Hospital
2000-2009
Harvard University
2000-2009
Lung Institute
2009
Université Laval
2009
University of California, San Francisco
2009
Background — Atherosclerotic coronary arteries are prone to constriction but the underlying causes incompletely understood. We tested hypothesis that endothelin-1 (ET-1), a potent vasoconstrictor, contributes heightened tone of atherosclerotic human arteries. Methods and Results In 8 patients with artery disease (CAD) angiographically smooth (normal), we infused BQ-123, an antagonist ET A receptor, into major (infused artery) at 40 nmol/min for 60 minutes. The in CAD contained >50%...
There is growing evidence that obstructive sleep apnea associated with coronary artery disease. However, there are no data on the course of stenosis after percutaneous intervention in patients apnea.To determine whether increased late lumen loss and restenosis intervention.78 disease who underwent elective were divided 2 groups: 43 an hypopnea - Index < 10/h (group I) 35 pt. AHI > II). Late loss, a marker restenosis, was determined using quantitative angiography 6.9 +/- 3.1...
Objective— The oxidative modification of low density lipoprotein (LDL) may play a role in the pathogenesis transplant-associated arteriosclerosis. Oxidized LDL (OxLDL) is immunogenic as well atherogenic, and level autoantibodies to OxLDL has been taken an index oxidant state LDL. Because endothelial dysfunction key initiation arteriosclerosis, we postulated that autoantibody associated with degree impairment coronary function. Methods Results— Coronary endothelium-dependent dilation was...
This report presents the results of an investigation on accumulation β-agonist residues in retinal tissue food producing animals. Three different species, calf, pig and turkey, were treated with six β-agonists analysed for applying a newly developed retina preparation procedure which provides sufficient sample material multiple analyses. The show that all selected accumulate retina, though varying concentrations. are discussed basis existing binding theories regard to their impact residue...
Transplant coronary arteriosclerosis (TCA) is the principal long-term complication in cardiac transplant recipients. The mediators responsible for vascular proliferation and vasoconstriction typical of TCA remain largely unknown. We tested whether endothelin-1 (ET-1), a potent vasoconstrictor mitogen, contributes to pathogenesis manifestations TCA.BQ-123, an ET-1 receptor-A antagonist, was infused into artery (40 nmol/min 60 minutes) 18 subjects, 6 + or - 4 years after transplantation....
Background: Coronary arteriosclerosis is the principal complication limiting long-term survival after heart transplantation. In humans, mediators responsible for vascular proliferation and vasoconstriction typical of TCA are unknown. Endothelin-1 (ET-1) a potent vasoconstrictor mitogen derived primarily from endothelial mononuclear cells. We tested hypothesis that ET-1’s biological activity increased in it may contribute to pathogenesis manifestations TCA. inhibited ET A receptor by...