- Schizophrenia research and treatment
- Child and Adolescent Psychosocial and Emotional Development
- Bipolar Disorder and Treatment
- Psychosomatic Disorders and Their Treatments
- Functional Brain Connectivity Studies
- Mental Health and Psychiatry
- Mental Health Treatment and Access
- Suicide and Self-Harm Studies
- Mental Health Research Topics
- Advanced Neuroimaging Techniques and Applications
- Obsessive-Compulsive Spectrum Disorders
- Adolescent and Pediatric Healthcare
- Child Abuse and Trauma
- Health disparities and outcomes
- Cannabis and Cannabinoid Research
- Neural dynamics and brain function
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Autism Spectrum Disorder Research
- Neuroscience and Music Perception
- Personality Disorders and Psychopathology
- Maternal Mental Health During Pregnancy and Postpartum
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Child and Adolescent Health
- Psychiatric care and mental health services
- Tryptophan and brain disorders
University College Dublin
2021-2025
University of Edinburgh
2022-2025
University of Oulu
2023-2025
Royal College of Surgeons in Ireland
2015-2024
Saint John of God Hospital
2022-2024
St John of God Hospital
2024
Beaumont Hospital
2009-2023
NHS Lothian
2023
Health Service Executive
2021-2022
Royal Edinburgh Hospital
2022
Epidemiological research has shown that hallucinations and delusions, the classic symptoms of psychosis, are far more prevalent in population than actual psychotic disorder. These especially childhood adolescence. Longitudinal demonstrated adolescence increase risk disorder adulthood. There been a lack research, however, on immediate clinicopathological significance adolescence.To investigate relationship between non-psychotic psychopathology community samples adolescents terms prevalence,...
Exposure to physical abuse and bullying during childhood was strongly predictive of psychotic experiences in individuals who had never before symptoms, stopping the trauma led a significant drop frequency experiences. The study adds weight calls for effective interventions curtail at school home reduce population.
Individuals who report psychotic-like experiences are at increased risk of future clinical psychotic disorder. They constitute a unique "high-risk" group for studying the developmental trajectory to schizophrenia and related illnesses. Previous research has used screening instruments identify this high-risk group, but validity these not yet been established. We administered questionnaire with 7 items designed assess 334 adolescents aged 11–13 years. Detailed interviews were subsequently...
IMPORTANCEUp to 1 million persons die by suicide annually.However, a lack of risk markers makes assessment one the most difficult areas clinical practice.OBJECTIVE To assess psychotic symptoms (attenuated or frank) as marker for attempt.DESIGN, SETTING, AND PARTICIPANTS Prospective cohort study 1112 school-based adolescents (aged 13-16 years), assessed at baseline and 3 12 months self-reported psychopathology, symptoms, attempts.MAIN OUTCOMES MEASURES Suicide attempts 3-and 12-month...
Background Countries worldwide are experiencing a third wave of the coronavirus disease 2019 (COVID-19) pandemic. Government-imposed restrictive measures continue with undetermined effects on physical and mental health. Aims To compare child adolescent health services (CAMHS) referrals over 11 months (January–November) in 2020, 2018 examine any impact different phases COVID-19 restrictions might have referral rates. Method Monthly CAMHS Health Service Executive data were examined, covering...
Children and adolescents who report psychotic symptoms appear to be at increased risk for disorders in adulthood - a putative ;symptomatic' high-risk group. However, little research has investigated whether those this population have rates of exposure traumatic events childhood, as seen patients illness.To examine with an rate experiences.Psychiatric interviews were carried out 211 aged between 12 15 years their parents part population-based study. The interview enquired about number early...
Background Adolescent cannabis use has been shown in many studies to increase the risk of later psychosis. Childhood trauma is associated with both substance misuse and for In this study our aim was investigate whether there a significant interaction between childhood increasing experiencing psychotic symptoms during adolescence. Method Psychiatric interviews using Schedule Affective Disorders Schizophrenia School-Age Children (K-SADS) semi-structured instrument were carried out 211...
CONTEXT Recent evidence from both clinical and population research has pointed to psychotic symptoms as potentially important markers of risk for suicidal behavior. However, our knowledge, there have been no epidemiological studies date that reported data on suicidality in individuals who clinically assessed OBJECTIVES To explore associations between nonpsychotic adolescents behavior (1) the general population, (2) with psychiatric disorder, (3) ideation. DESIGN Two independently conducted...
Recent community-based research has suggested that psychotic experiences act as markers of severity psychopathology. There has, however, been a lack clinic-based research. We wished to investigate, in clinical sample adolescents referred state-funded mental health service, the prevalence (attenuated or frank) and relationship with (i) affective, anxiety behavioural disorders, (ii) multimorbid psychopathology, (iii) global functioning, (iv) suicidal behaviour.The investigation was...
Urban residence is one of the most well-established risk factors for psychotic disorder, but evidence comes from a small group high-income countries.
While a great deal of research has been conducted on prodromal risk syndromes in relation to help-seeking individuals who present the clinic, there is lack general population. The current study aimed first establish whether could be detected non-help-seeking community-based adolescents and secondly characterize this group terms Axis-1 psychopathology functioning. We in-depth clinical interviews with population sample 212 school-going order assess for syndromes, psychopathology, global...
Neurocognitive dysfunction is well established in psychosis, but recent work suggests that processing speed deficits might represent a particularly important cognitive deficit. A number of significant confounds, however, such as disease chronicity and antipsychotic medication use, have been shown to affect speed, causing debate the core features psychosis. We adopted novel strategy testing neurocognitive performance "extended psychosis phenotype," involving community-based adolescents who...
Psychotic experiences are far more prevalent in the population than psychotic disorders and associated with a wide range of depressive, anxiety behavioral disorders, as well increased risk for disorder. Recently, have been highlighted potentially valuable clinical marker suicidal behavior. There few studies to date, however, assess predictor suicidality over time. We wished whether young persons ideation at baseline assessment who reported were higher persistence follow-up also but did not...
Introduction. A wide variety of neurocognitive deficits have been reported for help-seeking individuals who are at clinical or ultra high risk psychosis based on fulfilling set criteria prodromal syndromes/at mental states. We wished to extend this research by conducting the first population-based assessment syndromes and associated neurocognition. Methods. sample 212 school-based adolescents were assessed using from Structured Interview Prodromal Syndromes. The MATRICS consensus battery was...