A5102793012- Cardiac, Anesthesia and Surgical Outcomes
- Advanced biosensing and bioanalysis techniques
- Cancer, Hypoxia, and Metabolism
- CRISPR and Genetic Engineering
- RNA and protein synthesis mechanisms
- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
Guangzhou University of Chinese Medicine
2025
Shanghai University of Traditional Chinese Medicine
2023
Tsinghua University
2018
The accumulation of mitochondrial DNA (mtDNA) mutations in cells is strongly related to aging-associated diseases. Imaging single-nucleotide variation (SNV) mtDNA crucial for understanding the heteroplasmy mtDNAs that harbor pathogenic changes. Herein, we designed a CRISPR/Cas9-mediated proximity ligation assay (CasPLA) direct visualization ND4 and ND5 genes single cells. Taking advantage high specificity CRISPR/Cas9, CasPLA can be used image SNV gene at single-molecule resolution. Using...
To investigate the predictive value of physiological capacity and surgical stress scores for perioperative complications in radical resection colorectal cancer (CRC). A retrospective case-control study was performed from October 2021 to 2023 at a single center, involving patients scheduled CRC. Patients were divided into groups with without complications, propensity score matching minimize potential bias clinical confounding variables. General patient data, including demographic information,...
Developing effective therapy to inhibit postoperative recurrence and metastasis of colorectal cancer (CRC) is challenging significant reduce mortality morbidity. Here, a granular hydrogel, assembled from gelatin microgels by dialdehyde starch interpenetrated with in situ polymerized poly(sulfobetaine methacrylate-co-N-isopropylacrylamide) (P(SBMA-co-NIPAM)), prepared load lock Food Drug Administration (FDA)-approved indocyanine green (ICG) definite photothermal function biosafety for (PTT)...